SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		5 / 11 SER H  35
TRP H  47
TYR H  58
GLY H 104
LEU H 105
 None
 0.78A 1i9jH-4m1gH:
28.8
1i9jL-4m1gH:
15.7		 1i9jH-4m1gH:
65.45
1i9jL-4m1gH:
25.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		4 / 6 HIS H  98
LEU H 105
TRP H 108
VAL H  50
 None
 1.20A 1ibgH-4m1gH:
27.6		 1ibgH-4m1gH:
82.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		4 / 7 ASP H  89
SER H  84
SER H  17
ASN H  83
 None
 1.23A 1ig3A-4m1gH:
undetectable
1ig3B-4m1gH:
undetectable		 1ig3A-4m1gH:
21.43
1ig3B-4m1gH:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		5 / 12 SER H  35
TRP H  47
TYR H  58
GLY H 104
LEU H 105
 None
 0.80A 1vpoH-4m1gH:
27.9
1vpoL-4m1gH:
15.9		 1vpoH-4m1gH:
65.45
1vpoL-4m1gH:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		3 / 3 PRO H   9
LEU H 114
ARG H  38
 None
 0.78A 3aqiB-4m1gH:
undetectable		 3aqiB-4m1gH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		6 / 12 THR H  56
GLY H  33
GLY H  53
GLY H  54
ALA H  96
HIS H  98
 None
 1.48A 5c0oF-4m1gH:
undetectable		 5c0oF-4m1gH:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN
(Mus
musculus) 		5 / 5 SER H 117
ALA H 119
PHE H 151
LEU H 175
ASP H 178
 None
 1.09A 5mthA-4m1gH:
27.6		 5mthA-4m1gH:
61.61