SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		5 / 12 LEU A  60
LEU A 120
ILE A  86
ILE A 116
TYR A 144
 None
 1.31A 4a79A-4m1nA:
undetectable		 4a79A-4m1nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		5 / 12 LEU A  60
LEU A 120
ILE A  86
ILE A 116
TYR A 144
 None
 1.32A 4a79B-4m1nA:
undetectable		 4a79B-4m1nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		5 / 11 LEU A  60
LEU A 120
ILE A  86
ILE A 116
TYR A 144
 None
 1.29A 4a7aA-4m1nA:
undetectable		 4a7aA-4m1nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		5 / 12 PHE A  77
PRO A  84
GLN A 130
GLN A 151
LEU A  52
 None
 1.34A 4ac0A-4m1nA:
undetectable		 4ac0A-4m1nA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		3 / 3 LYS A 104
PRO A 105
SER A 106
 None
 0.37A 4k50I-4m1nA:
undetectable		 4k50I-4m1nA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4m1n UBIQUITIN
CONJUGATING ENZYME
UBC9
(Plasmodium
falciparum) 		4 / 7 LEU A  81
GLU A 132
LYS A 147
VAL A 148
 None
 1.14A 5jh7C-4m1nA:
undetectable		 5jh7C-4m1nA:
17.63