SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AOX_C_ACTC1001_0 (ALU JO CONSENSUS RNA SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN)	4m1x	UNCHARACTERIZED PROTEIN 201PHI2-1P060 (Pseudomonas phage 201phi2-1)	3 / 3	TYR A 49 THR A 51 THR A 46	None	0.51A	5aoxB-4m1xA: undetectable	5aoxB-4m1xA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AOX_F_ACTF1001_0 (ALU JO CONSENSUS RNA SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN)	4m1x	UNCHARACTERIZED PROTEIN 201PHI2-1P060 (Pseudomonas phage 201phi2-1)	3 / 3	TYR A 49 THR A 51 THR A 46	None	0.57A	5aoxE-4m1xA: undetectable	5aoxE-4m1xA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JM4_A_BEZA301_0 (14-3-3 PROTEIN ZETA/DELTA)	4m1x	UNCHARACTERIZED PROTEIN 201PHI2-1P060 (Pseudomonas phage 201phi2-1)	4 / 5	PHE A 66 ILE A 33 MET A 67 ARG A 70	None	1.48A	5jm4A-4m1xA: undetectable	5jm4A-4m1xA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA825_0 (GEPHYRIN)	4m1x	UNCHARACTERIZED PROTEIN 201PHI2-1P060 (Pseudomonas phage 201phi2-1)	3 / 3	LYS A 93 VAL A 74 ASP A 72	None	0.64A	6fgdA-4m1xA: undetectable	6fgdA-4m1xA: 12.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5AOX_C_ACTC1001_0","ALU JO CONSENSUS RNA;SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN","4m1x","UNCHARACTERIZED PROTEIN 201PHI2-1P060","Pseudomonas phage 201phi2-1",3,"TYR A  49;THR A  51;THR A  46","None","0.51A","5aoxB-4m1xA:undetectable","5aoxB-4m1xA:20.56"],["5AOX_F_ACTF1001_0","ALU JO CONSENSUS RNA;SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN","4m1x","UNCHARACTERIZED PROTEIN 201PHI2-1P060","Pseudomonas phage 201phi2-1",3,"TYR A  49;THR A  51;THR A  46","None","0.57A","5aoxE-4m1xA:undetectable","5aoxE-4m1xA:20.56"],["5JM4_A_BEZA301_0","14-3-3 PROTEIN ZETA\/DELTA","4m1x","UNCHARACTERIZED PROTEIN 201PHI2-1P060","Pseudomonas phage 201phi2-1",4,"PHE A  66;ILE A  33;MET A  67;ARG A  70","None","1.48A","5jm4A-4m1xA:undetectable","5jm4A-4m1xA:15.22"],["6FGD_A_ACTA825_0","GEPHYRIN","4m1x","UNCHARACTERIZED PROTEIN 201PHI2-1P060","Pseudomonas phage 201phi2-1",3,"LYS A  93;VAL A  74;ASP A  72","None","0.64A","6fgdA-4m1xA:undetectable","6fgdA-4m1xA:12.73"]]