SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m3c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 11 SER B 152
LEU B 108
GLY B 144
HIS B 226
GLU B 224
 MN  B 302 ( 4.2A)
None
None
None
None
 1.40A 1iolA-4m3cB:
undetectable		 1iolA-4m3cB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		5 / 11 SER F 152
LEU F 108
GLY F 144
HIS F 226
GLU F 224
 MN  F 302 ( 4.2A)
None
None
None
None
 1.43A 1iolA-4m3cF:
undetectable		 1iolA-4m3cF:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.91A 1jo3A-4m3cF:
undetectable		 1jo3A-4m3cF:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.91A 1jo3B-4m3cF:
undetectable		 1jo3B-4m3cF:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.88A 1jo4A-4m3cF:
undetectable		 1jo4A-4m3cF:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.88A 1jo4B-4m3cF:
undetectable		 1jo4B-4m3cF:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.92A 1ng8A-4m3cF:
undetectable		 1ng8A-4m3cF:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		3 / 3 ALA F  55
VAL F 208
TRP F 207
 None
 0.92A 1ng8B-4m3cF:
undetectable		 1ng8B-4m3cF:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 12 ALA B 105
GLY B 109
GLY B 104
ASP B 146
GLY B  49
 None
 0.96A 2qe6B-4m3cB:
undetectable		 2qe6B-4m3cB:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 11 LEU B 178
VAL B 198
ILE B  59
VAL B 123
ILE B 145
 None
 1.15A 2uxoB-4m3cB:
undetectable		 2uxoB-4m3cB:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 12 LEU B 204
ILE B 210
ILE B  57
ILE B  59
VAL B 198
 None
None
ABU  B 303 (-3.7A)
None
None
 0.96A 2ygoA-4m3cB:
undetectable		 2ygoA-4m3cB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 11 LEU B 204
VAL B 203
SER B  69
LEU B 179
VAL B 197
 None
 1.29A 3tbgA-4m3cB:
undetectable		 3tbgA-4m3cB:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 12 PHE B  70
GLY B 211
ILE B  57
VAL B 208
ALA B  91
 None
None
ABU  B 303 (-3.7A)
None
None
 1.11A 4a6eA-4m3cB:
undetectable		 4a6eA-4m3cB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		3 / 3 SER B 149
ASP B 137
ASP B 140
 None
MN  B 302 ( 2.7A)
None
 0.70A 4mwzA-4m3cB:
undetectable		 4mwzA-4m3cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		5 / 12 GLY F 106
GLY F 105
GLY F  89
ILE F 143
TYR F 140
 CA  F 301 ( 4.6A)
None
None
None
None
 0.98A 4rtmA-4m3cF:
undetectable		 4rtmA-4m3cF:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4m3c LECTIN BETA CHAIN
(Butea
monosperma) 		5 / 12 LEU B  94
LEU B 204
ILE B  59
LYS B   1
VAL B 198
 None
 0.98A 4y0sA-4m3cB:
undetectable		 4y0sA-4m3cB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 4m3c SEED LECTIN BETA
CHAIN
(Spatholobus
parviflorus) 		5 / 12 ALA F 124
LEU F 200
ILE F  59
VAL F 210
PHE F 233
 None
 1.32A 5vlmG-4m3cF:
undetectable		 5vlmG-4m3cF:
21.07