SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_D_CLMD221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4m5d	RIBOSOMAL RNA-PROCESSING PROTEIN 7 (Saccharomyces cerevisiae)	5 / 12	LEU B 141 PHE B 70 VAL B 16 PHE B 128 CYH B 137	None	1.48A	3u9fD-4m5dB: undetectable 3u9fE-4m5dB: undetectable	3u9fD-4m5dB: 22.15 3u9fE-4m5dB: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_G_CLMG221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4m5d	RIBOSOMAL RNA-PROCESSING PROTEIN 7 (Saccharomyces cerevisiae)	5 / 12	LEU B 141 PHE B 70 VAL B 16 PHE B 128 CYH B 137	None	1.50A	3u9fG-4m5dB: undetectable 3u9fH-4m5dB: undetectable	3u9fG-4m5dB: 22.15 3u9fH-4m5dB: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_C_IPHC101_0 (INSULIN)	4m5d	RIBOSOMAL RNA-PROCESSING PROTEIN 7 (Saccharomyces cerevisiae)	5 / 11	LEU B 55 CYH B 137 ALA B 39 VAL B 71 LEU B 74	None	1.16A	4p65C-4m5dB: undetectable 4p65D-4m5dB: undetectable 4p65J-4m5dB: undetectable 4p65L-4m5dB: undetectable	4p65C-4m5dB: 5.41 4p65D-4m5dB: 8.73 4p65J-4m5dB: 8.73 4p65L-4m5dB: 8.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3U9F_D_CLMD221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4m5d","RIBOSOMAL RNA-PROCESSING PROTEIN 7","Saccharomyces cerevisiae",5,"LEU B 141;PHE B  70;VAL B  16;PHE B 128;CYH B 137","None","1.48A","3u9fD-4m5dB:undetectable;3u9fE-4m5dB:undetectable","3u9fD-4m5dB:22.15;3u9fE-4m5dB:22.15"],["3U9F_G_CLMG221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","4m5d","RIBOSOMAL RNA-PROCESSING PROTEIN 7","Saccharomyces cerevisiae",5,"LEU B 141;PHE B  70;VAL B  16;PHE B 128;CYH B 137","None","1.50A","3u9fG-4m5dB:undetectable;3u9fH-4m5dB:undetectable","3u9fG-4m5dB:22.15;3u9fH-4m5dB:22.15"],["4P65_C_IPHC101_0","INSULIN","4m5d","RIBOSOMAL RNA-PROCESSING PROTEIN 7","Saccharomyces cerevisiae",5,"LEU B  55;CYH B 137;ALA B  39;VAL B  71;LEU B  74","None","1.16A","4p65C-4m5dB:undetectable;4p65D-4m5dB:undetectable;4p65J-4m5dB:undetectable;4p65L-4m5dB:undetectable","4p65C-4m5dB:5.41;4p65D-4m5dB:8.73;4p65J-4m5dB:8.73;4p65L-4m5dB:8.73"]]