SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		3 / 3 TRP A 342
VAL A 371
TRP A 128
 None
 1.08A 1c4dA-4m64A:
undetectable
1c4dB-4m64A:
undetectable		 1c4dA-4m64A:
4.00
1c4dB-4m64A:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 242
VAL A 376
TRP A 342
 None
 0.97A 1gmkA-4m64A:
undetectable
1gmkB-4m64A:
undetectable		 1gmkA-4m64A:
4.00
1gmkB-4m64A:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 242
VAL A 376
TRP A 342
 None
 0.82A 1gmkC-4m64A:
undetectable
1gmkD-4m64A:
undetectable		 1gmkC-4m64A:
4.00
1gmkD-4m64A:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 PHE A  16
ILE A 191
GLY A  14
THR A 194
VAL A 196
 None
 1.04A 1nv8A-4m64A:
undetectable		 1nv8A-4m64A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 PHE A  16
ILE A 191
GLY A  14
THR A 194
VAL A 196
 None
 1.06A 1nv8B-4m64A:
undetectable		 1nv8B-4m64A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 PHE A  16
ILE A 191
GLY A  14
THR A 194
VAL A 196
 None
 1.06A 1sg9A-4m64A:
undetectable		 1sg9A-4m64A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		4 / 5 PRO A  60
VAL A 371
THR A 222
GLY A 225
 None
 1.05A 3elzB-4m64A:
undetectable		 3elzB-4m64A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 409
LEU A 407
PHE A 412
ALA A 317
ASP A 320
 None
 1.09A 3tbgB-4m64A:
undetectable		 3tbgB-4m64A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 409
LEU A 407
PHE A 412
ALA A 317
ASP A 320
 None
 1.05A 3tbgD-4m64A:
undetectable		 3tbgD-4m64A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		4 / 7 ILE A 250
VAL A 390
ASN A 244
PHE A 386
 None
 0.98A 5hieC-4m64A:
undetectable		 5hieC-4m64A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A  28
LEU A  94
LEU A  91
THR A 119
 None
 1.06A 5hs6A-4m64A:
undetectable		 5hs6A-4m64A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4m64 MELIBIOSE CARRIER
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 415
THR A 425
ALA A 254
SER A 380
PHE A 386
 None
 1.23A 5iwuA-4m64A:
undetectable		 5iwuA-4m64A:
18.90