SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7
(Saccharomyces
cerevisiae) 		4 / 4 ILE F  98
LEU F  42
VAL F  40
ALA F 105
 None
 0.82A 1mz9A-4m7aF:
undetectable		 1mz9A-4m7aF:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7
(Saccharomyces
cerevisiae) 		4 / 5 ILE F  98
LEU F  42
VAL F  40
ALA F 105
 None
 0.79A 1mz9C-4m7aF:
undetectable		 1mz9C-4m7aF:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM4
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM8
(Saccharomyces
cerevisiae) 		4 / 8 ILE G  86
LEU G  81
LEU A  55
PHE A  37
 None
 0.88A 2vctB-4m7aG:
undetectable		 2vctB-4m7aG:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7
(Saccharomyces
cerevisiae) 		3 / 3 ALA F 105
ARG F  39
LYS F  41
 None
 1.03A 3kp3B-4m7aF:
undetectable		 3kp3B-4m7aF:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM8
(Saccharomyces
cerevisiae) 		5 / 12 GLN A  54
ASN A  40
ARG A  12
LEU A  38
ILE A  15
 None
 1.19A 4k36A-4m7aA:
undetectable		 4k36A-4m7aA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM8
(Saccharomyces
cerevisiae) 		5 / 12 GLN A  54
ASN A  40
ARG A  12
LEU A  38
ILE A  15
 None
 1.24A 4k36B-4m7aA:
undetectable		 4k36B-4m7aA:
13.73