SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 9 ASP A 173
SER A 179
TRP A 195
GLY A 196
GLY A 206
None
0.44A 1bcuH-4m7gA:
18.0
1bcuH-4m7gA:
32.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
1.00A 1c9sN-4m7gA:
undetectable
1c9sO-4m7gA:
undetectable
1c9sN-4m7gA:
17.16
1c9sO-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
1.02A 1c9sP-4m7gA:
undetectable
1c9sQ-4m7gA:
undetectable
1c9sP-4m7gA:
17.16
1c9sQ-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 9 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
1.00A 1c9sQ-4m7gA:
undetectable
1c9sR-4m7gA:
undetectable
1c9sQ-4m7gA:
17.16
1c9sR-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
1.00A 1c9sL-4m7gA:
undetectable
1c9sV-4m7gA:
undetectable
1c9sL-4m7gA:
17.16
1c9sV-4m7gA:
17.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 9 HIS A  42
ASP A 173
SER A 179
TRP A 195
GLY A 206
None
0.42A 1dwcH-4m7gA:
32.2
1dwcH-4m7gA:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
6 / 12 HIS A  42
ASP A 173
SER A 179
TRP A 195
GLY A 196
GLY A 206
None
0.43A 1etrH-4m7gA:
32.3
1etrH-4m7gA:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 8 ASP A 173
SER A 179
GLY A 196
GLY A 206
None
0.42A 1f5lA-4m7gA:
11.3
1f5lA-4m7gA:
30.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 9 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.99A 1gtfD-4m7gA:
undetectable
1gtfE-4m7gA:
undetectable
1gtfD-4m7gA:
17.16
1gtfE-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.96A 1gtfJ-4m7gA:
undetectable
1gtfK-4m7gA:
undetectable
1gtfJ-4m7gA:
17.16
1gtfK-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.98A 1gtfQ-4m7gA:
undetectable
1gtfR-4m7gA:
undetectable
1gtfQ-4m7gA:
17.16
1gtfR-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 9 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.98A 1gtfR-4m7gA:
undetectable
1gtfS-4m7gA:
undetectable
1gtfR-4m7gA:
17.16
1gtfS-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.99A 1gtfS-4m7gA:
undetectable
1gtfT-4m7gA:
undetectable
1gtfS-4m7gA:
17.16
1gtfT-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 8 THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.83A 1gtnE-4m7gA:
undetectable
1gtnF-4m7gA:
undetectable
1gtnE-4m7gA:
17.16
1gtnF-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
1.02A 1gtnT-4m7gA:
undetectable
1gtnU-4m7gA:
undetectable
1gtnT-4m7gA:
17.16
1gtnU-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
1.03A 1gtnL-4m7gA:
undetectable
1gtnV-4m7gA:
undetectable
1gtnL-4m7gA:
17.16
1gtnV-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
3 / 3 ASN A 223
ALA A  33
ASN A  35
None
0.68A 1n4fA-4m7gA:
undetectable
1n4fA-4m7gA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.01A 1t85A-4m7gA:
undetectable
1t85A-4m7gA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.05A 1t87A-4m7gA:
undetectable
1t87A-4m7gA:
20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 ASP A 173
SER A 179
GLY A 196
GLY A 206
None
0.16A 1tnlA-4m7gA:
33.9
1tnlA-4m7gA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.98A 1utdE-4m7gA:
undetectable
1utdF-4m7gA:
undetectable
1utdE-4m7gA:
17.16
1utdF-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.99A 1utdH-4m7gA:
undetectable
1utdI-4m7gA:
undetectable
1utdH-4m7gA:
17.16
1utdI-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.95A 1utdL-4m7gA:
undetectable
1utdM-4m7gA:
undetectable
1utdL-4m7gA:
17.16
1utdM-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.96A 1utdO-4m7gA:
undetectable
1utdP-4m7gA:
undetectable
1utdO-4m7gA:
17.16
1utdP-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.98A 1utdP-4m7gA:
undetectable
1utdQ-4m7gA:
undetectable
1utdP-4m7gA:
17.16
1utdQ-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
0.97A 1utdS-4m7gA:
undetectable
1utdT-4m7gA:
undetectable
1utdS-4m7gA:
17.16
1utdT-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 191
ALA A 119
ILE A 190
GLY A 206
THR A 174
None
1.00A 1utdU-4m7gA:
undetectable
1utdV-4m7gA:
undetectable
1utdU-4m7gA:
17.16
1utdV-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.97A 1utdL-4m7gA:
undetectable
1utdV-4m7gA:
undetectable
1utdL-4m7gA:
17.16
1utdV-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.99A 1yrcA-4m7gA:
undetectable
1yrcA-4m7gA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.04A 1yrdA-4m7gA:
undetectable
1yrdA-4m7gA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A 123
PHE A  26
GLY A 177
GLY A 125
ALA A 134
None
1.08A 2dpmA-4m7gA:
undetectable
2dpmA-4m7gA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.98A 2feuA-4m7gA:
undetectable
2feuA-4m7gA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.95A 2feuB-4m7gA:
undetectable
2feuB-4m7gA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A 174
ASP A 173
VAL A 144
LEU A 189
None
1.06A 2hdnE-4m7gA:
undetectable
2hdnF-4m7gA:
undetectable
2hdnH-4m7gA:
undetectable
2hdnE-4m7gA:
8.70
2hdnF-4m7gA:
22.70
2hdnH-4m7gA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 VAL A 144
LEU A 189
THR A 174
ASP A 173
None
1.04A 2hdnF-4m7gA:
undetectable
2hdnG-4m7gA:
undetectable
2hdnH-4m7gA:
undetectable
2hdnF-4m7gA:
22.70
2hdnG-4m7gA:
8.70
2hdnH-4m7gA:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 ASP A 173
SER A 179
GLY A 196
GLY A 206
None
0.31A 2otvA-4m7gA:
33.8
2otvA-4m7gA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
6 / 12 ASP A 173
SER A 179
TRP A 195
GLY A 196
GLY A 206
TYR A 208
None
0.40A 2p16A-4m7gA:
33.4
2p16A-4m7gA:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.07A 2v2gA-4m7gA:
undetectable
2v2gB-4m7gA:
undetectable
2v2gA-4m7gA:
25.29
2v2gB-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.06A 2v2gA-4m7gA:
undetectable
2v2gB-4m7gA:
undetectable
2v2gA-4m7gA:
25.29
2v2gB-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.07A 2v2gC-4m7gA:
undetectable
2v2gD-4m7gA:
undetectable
2v2gC-4m7gA:
25.29
2v2gD-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.06A 2v2gC-4m7gA:
undetectable
2v2gD-4m7gA:
undetectable
2v2gC-4m7gA:
25.29
2v2gD-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 8 THR A  67
VAL A  55
SER A  56
GLU A  95
None
0.97A 2v41C-4m7gA:
undetectable
2v41D-4m7gA:
undetectable
2v41C-4m7gA:
25.29
2v41D-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.06A 2v41E-4m7gA:
undetectable
2v41F-4m7gA:
undetectable
2v41E-4m7gA:
25.29
2v41F-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.04A 2v41E-4m7gA:
undetectable
2v41F-4m7gA:
undetectable
2v41E-4m7gA:
25.29
2v41F-4m7gA:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 8 THR A  67
VAL A  55
SER A  56
GLU A  95
None
1.05A 2v41G-4m7gA:
undetectable
2v41H-4m7gA:
undetectable
2v41G-4m7gA:
25.29
2v41H-4m7gA:
25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
7 / 12 ASP A 173
SER A 179
TRP A 195
GLY A 196
GLY A 198
GLY A 206
TYR A 208
None
0.47A 2w26A-4m7gA:
13.1
2w26A-4m7gA:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A  29
GLY A 180
ALA A 209
ALA A  17
VAL A  37
None
1.16A 2yvlB-4m7gA:
undetectable
2yvlB-4m7gA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 GLY A  29
GLY A 180
ALA A 209
ALA A  17
VAL A  37
None
1.12A 2yvlD-4m7gA:
undetectable
2yvlD-4m7gA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.09A 2zuhA-4m7gA:
undetectable
2zuhA-4m7gA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.03A 2zuiA-4m7gA:
undetectable
2zuiA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.99A 2zwtA-4m7gA:
undetectable
2zwtA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.00A 2zwuA-4m7gA:
undetectable
2zwuA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.20A 3bexC-4m7gA:
undetectable
3bexD-4m7gA:
undetectable
3bexC-4m7gA:
21.01
3bexD-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 LEU A  92
THR A  44
VAL A  16
GLY A  28
ILE A  52
None
1.19A 3bexC-4m7gA:
undetectable
3bexD-4m7gA:
undetectable
3bexC-4m7gA:
21.01
3bexD-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.21A 3bexE-4m7gA:
undetectable
3bexF-4m7gA:
undetectable
3bexE-4m7gA:
21.01
3bexF-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 LEU A  92
THR A  44
VAL A  16
GLY A  28
ILE A  52
None
1.20A 3bexE-4m7gA:
undetectable
3bexF-4m7gA:
undetectable
3bexE-4m7gA:
21.01
3bexF-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.23A 3bf1A-4m7gA:
undetectable
3bf1B-4m7gA:
undetectable
3bf1A-4m7gA:
21.01
3bf1B-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 LEU A  92
THR A  44
VAL A  16
GLY A  28
ILE A  52
None
1.21A 3bf1A-4m7gA:
undetectable
3bf1B-4m7gA:
undetectable
3bf1A-4m7gA:
21.01
3bf1B-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.22A 3bf1C-4m7gA:
undetectable
3bf1D-4m7gA:
undetectable
3bf1C-4m7gA:
21.01
3bf1D-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 LEU A  92
THR A  44
VAL A  16
GLY A  28
ILE A  52
None
1.18A 3bf1C-4m7gA:
undetectable
3bf1D-4m7gA:
undetectable
3bf1C-4m7gA:
21.01
3bf1D-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.20A 3bf1E-4m7gA:
undetectable
3bf1F-4m7gA:
undetectable
3bf1E-4m7gA:
21.01
3bf1F-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 11 LEU A  92
THR A  44
VAL A  16
GLY A  28
ILE A  52
None
1.20A 3bf1E-4m7gA:
undetectable
3bf1F-4m7gA:
undetectable
3bf1E-4m7gA:
21.01
3bf1F-4m7gA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.94A 3fwfA-4m7gA:
undetectable
3fwfA-4m7gA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.91A 3fwfB-4m7gA:
undetectable
3fwfB-4m7gA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.97A 3fwjA-4m7gA:
undetectable
3fwjA-4m7gA:
20.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
7 / 11 HIS A  42
ASP A 173
GLN A 176
SER A 179
TRP A 195
GLY A 196
GLY A 206
None
0.26A 3gy3A-4m7gA:
34.6
3gy3A-4m7gA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.92A 3l63A-4m7gA:
undetectable
3l63A-4m7gA:
20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 6 SER A 179
TRP A 195
GLY A 196
GLY A 206
None
0.15A 3rxfA-4m7gA:
14.6
3rxfA-4m7gA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.97A 3wrhA-4m7gA:
undetectable
3wrhA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.97A 3wrjA-4m7gA:
undetectable
3wrjA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.96A 3wrlA-4m7gA:
undetectable
3wrlA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.94A 3wrlE-4m7gA:
undetectable
3wrlE-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.95A 3wrmA-4m7gA:
undetectable
3wrmA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.99A 3wrmF-4m7gA:
undetectable
3wrmF-4m7gA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 5 HIS A  42
GLN A 176
GLY A 177
SER A 179
None
0.90A 4fu8A-4m7gA:
33.8
4fu8A-4m7gA:
32.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 8 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.04A 4l4bA-4m7gA:
undetectable
4l4bA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
1.01A 4l4gA-4m7gA:
undetectable
4l4gA-4m7gA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 12 VAL A  16
GLY A  28
ILE A  52
LEU A  92
THR A  44
None
1.27A 4o5fA-4m7gA:
undetectable
4o5fB-4m7gA:
undetectable
4o5fA-4m7gA:
21.21
4o5fB-4m7gA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A 174
GLY A 196
TYR A 208
GLY A 206
None
0.88A 4rdxA-4m7gA:
undetectable
4rdxA-4m7gA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5eevA-4m7gA:
undetectable
5eevB-4m7gA:
undetectable
5eevA-4m7gA:
17.16
5eevB-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5eewA-4m7gA:
undetectable
5eewB-4m7gA:
undetectable
5eewA-4m7gA:
17.16
5eewB-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5eexA-4m7gA:
undetectable
5eexB-4m7gA:
undetectable
5eexA-4m7gA:
17.16
5eexB-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5eeyA-4m7gA:
undetectable
5eeyB-4m7gA:
undetectable
5eeyA-4m7gA:
17.16
5eeyB-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5eezA-4m7gA:
undetectable
5eezB-4m7gA:
undetectable
5eezA-4m7gA:
17.16
5eezB-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5ef0A-4m7gA:
undetectable
5ef0B-4m7gA:
undetectable
5ef0A-4m7gA:
17.16
5ef0B-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5ef1A-4m7gA:
undetectable
5ef1B-4m7gA:
undetectable
5ef1A-4m7gA:
17.16
5ef1B-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5ef2A-4m7gA:
undetectable
5ef2B-4m7gA:
undetectable
5ef2A-4m7gA:
17.16
5ef2B-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
5 / 10 GLY A 206
THR A 174
GLY A 191
ALA A 119
ILE A 190
None
0.94A 5ef3A-4m7gA:
undetectable
5ef3B-4m7gA:
undetectable
5ef3A-4m7gA:
17.16
5ef3B-4m7gA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 THR A  44
LEU A  92
VAL A  37
VAL A 192
None
0.94A 5wk9A-4m7gA:
undetectable
5wk9A-4m7gA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspor
a
erythraea)
4 / 7 SER A  69
SER A  56
GLY A  66
LEU A  31
None
1.06A 6btxA-4m7gA:
undetectable
6btxA-4m7gA:
18.33