SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 6 ALA A 260
TYR A 245
ILE A 233
ILE A 266
 None
 1.09A 2dcfA-4m7oA:
undetectable		 2dcfA-4m7oA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 6 LEU A  87
LEU A 114
PRO A  97
VAL A 122
 None
 1.21A 2dqyC-4m7oA:
undetectable		 2dqyC-4m7oA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 6 LEU A 285
LEU A 288
ILE A 168
ARG A 289
 None
 0.92A 2rlfC-4m7oA:
undetectable
2rlfD-4m7oA:
undetectable		 2rlfC-4m7oA:
11.11
2rlfD-4m7oA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 12 SER A  48
THR A 160
ASP A 165
VAL A 164
ILE A 133
 None
 1.19A 2wa2A-4m7oA:
undetectable		 2wa2A-4m7oA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		3 / 3 TYR A  71
GLU A 283
THR A 160
 None
 0.93A 2y7hB-4m7oA:
1.7		 2y7hB-4m7oA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		4 / 7 ALA A 260
TYR A 245
ILE A 233
ILE A 266
 None
 1.06A 2zm7A-4m7oA:
undetectable		 2zm7A-4m7oA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 4m7o IRON-BINDING PROTEIN
(Staphylococcus
epidermidis) 		5 / 12 GLY A 284
SER A 275
PRO A 277
GLY A 278
ASP A 290
 None
 1.42A 3r24A-4m7oA:
2.3		 3r24A-4m7oA:
undetectable