SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4m7s BTRN
(Bacillus
circulans) 		4 / 8 PHE A  59
LEU A  71
GLY A  76
ASP A  72
 None
 0.96A 1rmtC-4m7sA:
2.4		 1rmtC-4m7sA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 4m7s BTRN
(Bacillus
circulans) 		5 / 11 VAL A  12
GLU A  64
TYR A  90
LEU A 104
ILE A  89
 None
 1.30A 1t6zB-4m7sA:
undetectable		 1t6zB-4m7sA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4m7s BTRN
(Bacillus
circulans) 		5 / 12 TYR A  90
VAL A 240
SER A   6
ARG A  86
ILE A 109
 None
 1.20A 1xvaA-4m7sA:
undetectable		 1xvaA-4m7sA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4m7s BTRN
(Bacillus
circulans) 		4 / 7 CYH A  16
CYH A  20
HIS A 117
HIS A  60
 SF4  A 502 (-2.4A)
SF4  A 502 (-2.3A)
SF4  A 502 (-3.8A)
SF4  A 502 ( 4.9A)
 1.22A 1yvmA-4m7sA:
undetectable		 1yvmA-4m7sA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4m7s BTRN
(Bacillus
circulans) 		5 / 12 PHE A 214
THR A 179
VAL A 178
LEU A  48
ILE A 205
 None
 1.34A 2fj1A-4m7sA:
undetectable		 2fj1A-4m7sA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4m7s BTRN
(Bacillus
circulans) 		4 / 5 LEU A  44
GLY A 182
ILE A 208
ILE A 205
 None
 0.71A 2q9rA-4m7sA:
undetectable		 2q9rA-4m7sA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4m7s BTRN
(Bacillus
circulans) 		3 / 3 ASN A 234
ASN A 236
GLU A 189
 None
 0.85A 3kpdC-4m7sA:
undetectable		 3kpdC-4m7sA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4m7s BTRN
(Bacillus
circulans) 		3 / 3 ASN A 234
ASN A 236
GLU A 189
 None
 0.86A 3kpdB-4m7sA:
undetectable		 3kpdB-4m7sA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4m7s BTRN
(Bacillus
circulans) 		5 / 10 ILE A   8
PHE A   5
ILE A  82
LEU A  51
HIS A 204
 None
 1.27A 3o1cA-4m7sA:
undetectable		 3o1cA-4m7sA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4m7s BTRN
(Bacillus
circulans) 		5 / 10 ILE A   8
PHE A   5
ILE A  82
LEU A  51
HIS A 204
 None
 1.28A 3o1xA-4m7sA:
undetectable		 3o1xA-4m7sA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4m7s BTRN
(Bacillus
circulans) 		5 / 10 ILE A   8
PHE A   5
ILE A  82
LEU A  51
HIS A 204
 None
 1.27A 3qgzA-4m7sA:
undetectable		 3qgzA-4m7sA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4m7s BTRN
(Bacillus
circulans) 		3 / 3 ASN A  17
ASP A  94
ASN A  92
 None
None
SF4  A 502 (-4.5A)
 0.76A 4agaA-4m7sA:
undetectable		 4agaA-4m7sA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4m7s BTRN
(Bacillus
circulans) 		5 / 12 TYR A  22
CYH A  23
TYR A  62
GLU A  64
ASN A  92
 None
SF4  A 502 (-2.4A)
None
None
SF4  A 502 (-4.5A)
 0.76A 4k36B-4m7sA:
13.7		 4k36B-4m7sA:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7T_A_SAMA503_0
(BTRN)		 4m7s BTRN
(Bacillus
circulans) 		6 / 11 TYR A  22
TYR A  62
GLU A  64
TYR A  90
THR A 115
HIS A 117
 None
None
None
None
None
SF4  A 502 (-3.8A)
 0.72A 4m7tA-4m7sA:
31.3		 4m7tA-4m7sA:
92.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 4m7s BTRN
(Bacillus
circulans) 		5 / 12 VAL A 184
TYR A  41
ILE A 200
PHE A   5
PHE A  53
 None
 1.45A 6j20A-4m7sA:
undetectable		 6j20A-4m7sA:
19.28