SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 10 ARG A  88
THR A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.39A 1jdvA-4m7wA:
34.4
1jdvD-4m7wA:
34.4		 1jdvA-4m7wA:
32.21
1jdvD-4m7wA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 10 ARG A  88
THR A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.38A 1jdvB-4m7wA:
34.7
1jdvC-4m7wA:
35.7		 1jdvB-4m7wA:
32.21
1jdvC-4m7wA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 10 ARG A  88
THR A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.39A 1jdvA-4m7wA:
34.4
1jdvD-4m7wA:
34.4		 1jdvA-4m7wA:
32.21
1jdvD-4m7wA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 12 ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.35A 1jdvE-4m7wA:
34.5
1jdvF-4m7wA:
35.7		 1jdvE-4m7wA:
32.21
1jdvF-4m7wA:
32.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 12 LEU A  86
LEU A 198
ALA A 142
ALA A 138
LEU A 236
 None
 1.35A 1kt5A-4m7wA:
undetectable		 1kt5A-4m7wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 THR A  50
GLY A  48
VAL A  38
ALA A   8
ILE A   6
 None
 1.10A 1likA-4m7wA:
undetectable		 1likA-4m7wA:
22.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.42A 1odiA-4m7wA:
25.8		 1odiA-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.39A 1odiB-4m7wA:
35.5		 1odiB-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.40A 1odiC-4m7wA:
35.7		 1odiC-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.42A 1odiD-4m7wA:
35.6		 1odiD-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.36A 1odiE-4m7wA:
35.7		 1odiE-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.39A 1odiF-4m7wA:
35.5		 1odiF-4m7wA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 9 MET A  65
ARG A  88
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.31A 1pk7A-4m7wA:
39.3		 1pk7A-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 10 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.54A 1pk7C-4m7wA:
38.8		 1pk7C-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 10 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.45A 1pk9A-4m7wA:
39.2		 1pk9A-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 9 MET A  65
ARG A  88
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.30A 1pk9B-4m7wA:
39.8		 1pk9B-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.60A 1pk9C-4m7wA:
37.2		 1pk9C-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 10 MET A  65
ARG A  88
GLY A  93
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.27A 1pw7A-4m7wA:
39.3		 1pw7A-4m7wA:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 9 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.46A 1pw7B-4m7wA:
39.3		 1pw7B-4m7wA:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 9 MET A  65
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.53A 1pw7C-4m7wA:
38.8		 1pw7C-4m7wA:
51.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.41A 1vhwA-4m7wA:
39.5
1vhwD-4m7wA:
39.6		 1vhwA-4m7wA:
48.28
1vhwD-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 9 MET A  65
ARG A  88
GLY A  93
VAL A 179
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
 0.42A 1vhwB-4m7wA:
39.3
1vhwF-4m7wA:
38.9		 1vhwB-4m7wA:
48.28
1vhwF-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.43A 1vhwC-4m7wA:
39.6
1vhwE-4m7wA:
39.4		 1vhwC-4m7wA:
48.28
1vhwE-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.42A 1vhwA-4m7wA:
39.5
1vhwD-4m7wA:
39.6		 1vhwA-4m7wA:
48.28
1vhwD-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.41A 1vhwC-4m7wA:
39.6
1vhwE-4m7wA:
39.4		 1vhwC-4m7wA:
48.28
1vhwE-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 10 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.42A 1vhwB-4m7wA:
39.3
1vhwF-4m7wA:
38.9		 1vhwB-4m7wA:
48.28
1vhwF-4m7wA:
48.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 10 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.45A 1z35A-4m7wA:
37.9		 1z35A-4m7wA:
45.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 9 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.35A 1z37A-4m7wA:
37.7		 1z37A-4m7wA:
45.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 9 MET A 181
ARG A  88
THR A  91
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
PO4  A 400 ( 4.4A)
None
 1.43A 1z37A-4m7wA:
37.7		 1z37A-4m7wA:
45.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.47A 2ac7A-4m7wA:
38.7
2ac7B-4m7wA:
38.7		 2ac7A-4m7wA:
61.63
2ac7B-4m7wA:
61.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.47A 2ac7A-4m7wA:
38.7
2ac7B-4m7wA:
38.7		 2ac7A-4m7wA:
61.63
2ac7B-4m7wA:
61.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		4 / 7 THR A 199
LEU A 177
VAL A 154
VAL A 135
 None
 0.94A 2cppA-4m7wA:
undetectable		 2cppA-4m7wA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		3 / 3 PRO A 128
ASN A 117
ARG A 120
 None
 1.00A 2qeuB-4m7wA:
undetectable		 2qeuB-4m7wA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 THR A  91
GLY A  93
PHE A 160
GLU A 180
MET A 181
 PO4  A 400 (-3.5A)
None
None
None
None
 0.68A 3kvrA-4m7wA:
25.6		 3kvrA-4m7wA:
27.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 THR A  91
GLY A  93
PHE A 160
GLU A 180
MET A 181
 PO4  A 400 (-3.5A)
None
None
None
None
 0.66A 3kvrB-4m7wA:
25.5		 3kvrB-4m7wA:
27.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 9 MET A  65
ARG A  88
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
 0.42A 3u40A-4m7wA:
37.3
3u40F-4m7wA:
36.4		 3u40A-4m7wA:
46.80
3u40F-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 10 MET A  65
ARG A  88
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
 0.41A 3u40B-4m7wA:
36.8
3u40C-4m7wA:
37.0		 3u40B-4m7wA:
46.80
3u40C-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 12 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.48A 3u40B-4m7wA:
36.8
3u40C-4m7wA:
37.0		 3u40B-4m7wA:
46.80
3u40C-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.48A 3u40D-4m7wA:
37.3
3u40E-4m7wA:
36.3		 3u40D-4m7wA:
46.80
3u40E-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 12 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.55A 3u40D-4m7wA:
37.3
3u40E-4m7wA:
36.3		 3u40D-4m7wA:
46.80
3u40E-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 10 MET A  65
ARG A  88
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
None
 0.57A 3u40A-4m7wA:
37.3
3u40F-4m7wA:
36.4		 3u40A-4m7wA:
46.80
3u40F-4m7wA:
46.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		10 / 11 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.52A 3uawA-4m7wA:
39.5		 3uawA-4m7wA:
61.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 11 MET A 181
ARG A  88
THR A  91
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
PO4  A 400 ( 4.4A)
None
None
 1.48A 3uawA-4m7wA:
39.5		 3uawA-4m7wA:
61.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 10 MET A  65
ARG A  88
THR A  91
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
PO4  A 400 (-3.5A)
None
None
None
None
PO4  A 400 ( 4.4A)
 0.33A 3uayA-4m7wA:
40.4		 3uayA-4m7wA:
61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.41A 4d9hA-4m7wA:
38.6		 4d9hA-4m7wA:
59.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 9 MET A  65
GLY A  93
VAL A 179
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.68A 4da6A-4m7wA:
38.4		 4da6A-4m7wA:
59.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 10 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.35A 4da7A-4m7wA:
38.7		 4da7A-4m7wA:
59.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		9 / 11 MET A  65
ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 None
PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.54A 4danA-4m7wA:
38.2		 4danA-4m7wA:
59.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		8 / 12 ARG A  88
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 PO4  A 400 (-3.0A)
None
None
None
None
PO4  A 400 ( 4.4A)
None
None
 0.54A 4danA-4m7wA:
38.2
4danB-4m7wA:
38.4		 4danA-4m7wA:
59.00
4danB-4m7wA:
59.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		4 / 8 THR A 199
LEU A 177
VAL A 154
VAL A 135
 None
 0.93A 4l4aA-4m7wA:
undetectable		 4l4aA-4m7wA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		4 / 8 THR A 199
LEU A 177
VAL A 154
VAL A 135
 None
 0.90A 4l4dA-4m7wA:
undetectable		 4l4dA-4m7wA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 THR A 199
GLY A  90
THR A  91
ALA A  92
ASP A 205
 None
PO4  A 400 (-3.6A)
PO4  A 400 (-3.5A)
None
None
 1.49A 4qvnH-4m7wA:
undetectable
4qvnI-4m7wA:
undetectable		 4qvnH-4m7wA:
23.27
4qvnI-4m7wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 THR A 199
GLY A  90
THR A  91
ALA A  92
ASP A 205
 None
PO4  A 400 (-3.6A)
PO4  A 400 (-3.5A)
None
None
 1.47A 4qvnV-4m7wA:
undetectable
4qvnW-4m7wA:
undetectable		 4qvnV-4m7wA:
23.27
4qvnW-4m7wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 THR A 199
GLY A  90
THR A  91
ALA A  92
ASP A 205
 None
PO4  A 400 (-3.6A)
PO4  A 400 (-3.5A)
None
None
 1.50A 4qvqV-4m7wA:
undetectable
4qvqW-4m7wA:
undetectable		 4qvqV-4m7wA:
23.27
4qvqW-4m7wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 THR A 199
GLY A  90
THR A  91
ALA A  92
ASP A 205
 None
PO4  A 400 (-3.6A)
PO4  A 400 (-3.5A)
None
None
 1.45A 4qwuH-4m7wA:
undetectable
4qwuI-4m7wA:
undetectable		 4qwuH-4m7wA:
23.27
4qwuI-4m7wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 THR A 199
GLY A  90
THR A  91
ALA A  92
ASP A 205
 None
PO4  A 400 (-3.6A)
PO4  A 400 (-3.5A)
None
None
 1.44A 4qwuV-4m7wA:
undetectable
4qwuW-4m7wA:
undetectable		 4qwuV-4m7wA:
23.27
4qwuW-4m7wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 12 GLY A  66
GLU A 182
GLY A  64
GLY A  21
SER A  69
 None
PO4  A 400 ( 4.4A)
None
PO4  A 400 (-3.2A)
None
 0.95A 4uckA-4m7wA:
undetectable		 4uckA-4m7wA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 12 SER A 131
LEU A 134
VAL A  83
ILE A  17
GLY A 194
 None
 0.96A 4y8wC-4m7wA:
undetectable		 4y8wC-4m7wA:
18.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 9 MET A  65
ARG A  88
GLY A  93
VAL A 179
MET A 181
GLU A 182
 None
PO4  A 400 (-3.0A)
None
None
None
PO4  A 400 ( 4.4A)
 0.46A 5i3cA-4m7wA:
39.4		 5i3cA-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		6 / 10 MET A  65
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
 None
None
None
None
None
PO4  A 400 ( 4.4A)
 0.50A 5i3cB-4m7wA:
39.4		 5i3cB-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
ASP A 205
 None
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.81A 5i3cC-4m7wA:
39.7		 5i3cC-4m7wA:
51.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		7 / 11 MET A  65
GLY A  93
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 None
None
None
None
None
PO4  A 400 ( 4.4A)
None
 0.49A 5i3cC-4m7wA:
39.7		 5i3cC-4m7wA:
51.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 ALA A 130
THR A 129
ALA A 151
GLY A 152
ALA A 107
 None
 1.01A 5lf3H-4m7wA:
undetectable
5lf3I-4m7wA:
undetectable		 5lf3H-4m7wA:
23.94
5lf3I-4m7wA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 10 ALA A 130
THR A 129
ALA A 151
GLY A 152
ALA A 107
 None
 1.02A 5lf3V-4m7wA:
undetectable
5lf3W-4m7wA:
undetectable		 5lf3V-4m7wA:
23.94
5lf3W-4m7wA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 ALA A 130
THR A 129
ALA A 151
GLY A 152
ALA A 107
 None
 1.00A 5lf7H-4m7wA:
undetectable
5lf7I-4m7wA:
undetectable		 5lf7H-4m7wA:
23.94
5lf7I-4m7wA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Leptotrichia
buccalis) 		5 / 11 ALA A 130
THR A 129
ALA A 151
GLY A 152
ALA A 107
 None
 0.99A 5lf7V-4m7wA:
undetectable
5lf7W-4m7wA:
undetectable		 5lf7V-4m7wA:
23.94
5lf7W-4m7wA:
21.27