SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 206
ALA A 264
ILE A 261
ALA A 218
VAL A 214
 None
 0.88A 2b7zB-4m98A:
undetectable		 2b7zB-4m98A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		6 / 12 GLY A 380
ALA A 379
ILE A 355
THR A 371
VAL A 386
ILE A 385
 None
 1.37A 3d1yA-4m98A:
undetectable		 3d1yA-4m98A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 302
VAL A 295
ILE A 289
ILE A 324
VAL A 331
 None
 1.01A 3d1zA-4m98A:
undetectable		 3d1zA-4m98A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 11 MET A 308
LEU A 217
LEU A 202
GLY A 211
HIS A 210
 None
 1.24A 3hm1B-4m98A:
undetectable		 3hm1B-4m98A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 11 MET A 308
LEU A 217
LEU A 202
GLY A 211
HIS A 210
 None
 1.25A 3uudA-4m98A:
undetectable		 3uudA-4m98A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 THR A 372
GLY A 374
VAL A 377
PRO A 390
 None
 1.15A 4grkA-4m98A:
undetectable		 4grkA-4m98A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ASP A 232
VAL A 265
ALA A 264
VAL A 204
GLY A 208
 None
 1.05A 4mm4B-4m98A:
undetectable		 4mm4B-4m98A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		6 / 12 GLY A 380
ALA A 379
ILE A 355
THR A 371
VAL A 386
ILE A 385
 None
 1.36A 5kqxA-4m98A:
undetectable		 5kqxA-4m98A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		6 / 12 ASP A 231
LEU A 230
ALA A 203
PRO A 286
GLY A 304
LEU A 285
 None
 1.30A 6b0iB-4m98A:
undetectable		 6b0iB-4m98A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 302
VAL A 295
ILE A 289
ILE A 324
VAL A 331
 None
 0.93A 6dj1B-4m98A:
undetectable		 6dj1B-4m98A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 4m98 PILIN GLYCOSYLATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 302
VAL A 295
ILE A 289
ILE A 324
VAL A 331
 None
 0.96A 6dj2B-4m98A:
undetectable		 6dj2B-4m98A:
19.43