SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A 192
ALA A 152
GLY A 151
ALA A 149
ILE A 166
 None
 0.83A 1bx4A-4m9cA:
undetectable		 1bx4A-4m9cA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		4 / 7 CYH A 154
TYR A 135
CYH A 140
HIS A 138
 None
 1.40A 1yvmA-4m9cA:
undetectable		 1yvmA-4m9cA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		4 / 5 ALA A 152
ALA A 164
ALA A 187
VAL A 205
 None
 0.88A 2nyrB-4m9cA:
undetectable		 2nyrB-4m9cA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A  12
GLY A  14
ILE A  70
ASN A  72
ASP A  37
 None
 1.12A 3ckkA-4m9cA:
undetectable		 3ckkA-4m9cA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		4 / 7 PHE A 148
PHE A 128
SER A 134
TYR A 135
 None
 1.41A 3hggA-4m9cA:
undetectable		 3hggA-4m9cA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		3 / 3 LYS A  78
VAL A  74
HIS A 163
 None
 1.10A 3tj7A-4m9cA:
undetectable		 3tj7A-4m9cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A 156
LEU A 181
CYH A 140
HIS A 159
ILE A 160
 None
 0.80A 4krhA-4m9cA:
undetectable		 4krhA-4m9cA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A 156
LEU A 181
CYH A 140
HIS A 159
ILE A 160
 None
 0.84A 4krhB-4m9cA:
undetectable		 4krhB-4m9cA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 VAL A  21
GLN A  24
ALA A  69
VAL A  17
LEU A  83
 None
 1.22A 5hv1A-4m9cA:
undetectable		 5hv1A-4m9cA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		3 / 3 ALA A 130
GLN A  94
THR A 116
 None
 0.71A 5n0oA-4m9cA:
2.1		 5n0oA-4m9cA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		5 / 12 ILE A 158
GLY A 156
THR A 119
ILE A 166
ILE A 172
 None
 1.07A 6emuB-4m9cA:
3.8		 6emuB-4m9cA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4m9c BACTERIAL
TRANSFERASE
HEXAPEPTIDE (THREE
REPEATS) FAMILY
PROTEIN
(Acinetobacter
baumannii) 		4 / 6 ASN A 131
PRO A 150
ILE A 132
GLU A  16
 None
 1.04A 6h7uA-4m9cA:
undetectable		 6h7uA-4m9cA:
17.66