SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 PHE A 309
VAL A 356
VAL A 314
GLN A  10
 None
 0.96A 1e7aB-4m9dA:
1.7		 1e7aB-4m9dA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 11 GLU A  14
GLY A  17
THR A  20
GLY A  40
GLU A 220
 MLI  A 502 (-4.7A)
MLI  A 502 (-3.2A)
None
MLI  A 502 (-4.8A)
None
 1.09A 1i7qA-4m9dA:
undetectable		 1i7qA-4m9dA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 10 GLU A  14
GLY A  17
THR A  20
GLY A  40
GLU A 220
 MLI  A 502 (-4.7A)
MLI  A 502 (-3.2A)
None
MLI  A 502 (-4.8A)
None
 1.09A 1i7qC-4m9dA:
undetectable		 1i7qC-4m9dA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 1jffB-4m9dA:
undetectable		 1jffB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 246
GLN A  34
VAL A   5
ALA A 244
 None
 0.86A 1p6kA-4m9dA:
undetectable		 1p6kA-4m9dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 5 GLY A 245
ILE A 243
VAL A   5
SER A 321
 None
 1.03A 1rs7A-4m9dA:
undetectable		 1rs7A-4m9dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 5 GLY A 246
ILE A 243
VAL A   5
SER A 321
 None
 1.00A 1rs7A-4m9dA:
undetectable		 1rs7A-4m9dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 246
ILE A 243
VAL A   5
SER A 321
 None
 1.00A 1rs7B-4m9dA:
undetectable		 1rs7B-4m9dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 7 VAL A 206
VAL A 217
CYH A 201
ARG A 101
 None
 1.17A 1t46A-4m9dA:
undetectable		 1t46A-4m9dA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLY A 221
GLY A  40
HIS A  41
VAL A 247
VAL A   7
 None
MLI  A 502 (-4.8A)
MLI  A 502 (-4.2A)
None
None
 1.04A 1vptA-4m9dA:
undetectable		 1vptA-4m9dA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 THR A 238
THR A 128
GLY A  36
GLY A 131
ILE A  68
 AMP  A 501 (-3.6A)
AMP  A 501 ( 2.8A)
None
None
None
 1.07A 2b25A-4m9dA:
2.6		 2b25A-4m9dA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLU A 295
ILE A 337
LEU A 340
SER A 270
ILE A 289
 None
 1.13A 2e7fA-4m9dA:
undetectable		 2e7fA-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
GLY A 307
SER A 270
GLN A  10
 None
 1.44A 2e7fB-4m9dA:
undetectable		 2e7fB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
SER A 270
GLN A  10
ILE A 289
 None
 1.21A 2e7fB-4m9dA:
undetectable		 2e7fB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 11 GLU A  14
GLY A  17
THR A  20
GLY A  40
GLU A 220
 MLI  A 502 (-4.7A)
MLI  A 502 (-3.2A)
None
MLI  A 502 (-4.8A)
None
 1.18A 2fn1A-4m9dA:
undetectable		 2fn1A-4m9dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 11 GLU A  14
GLY A  17
THR A  20
GLY A  40
GLU A 220
 MLI  A 502 (-4.7A)
MLI  A 502 (-3.2A)
None
MLI  A 502 (-4.8A)
None
 1.19A 2fn1B-4m9dA:
undetectable		 2fn1B-4m9dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 2hxfB-4m9dA:
undetectable		 2hxfB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 2hxhB-4m9dA:
undetectable		 2hxhB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
GLY A 307
SER A 270
GLN A  10
 None
 1.49A 2ogyA-4m9dA:
undetectable		 2ogyA-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
SER A 270
GLN A  10
ILE A 289
 None
 1.20A 2ogyA-4m9dA:
undetectable		 2ogyA-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
GLY A 307
SER A 270
GLN A  10
 None
 1.45A 2ogyB-4m9dA:
undetectable		 2ogyB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		6 / 12 GLU A 295
ILE A 337
LEU A 340
SER A 270
GLN A  10
ILE A 289
 None
 1.19A 2ogyB-4m9dA:
undetectable		 2ogyB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 2p4nB-4m9dA:
undetectable		 2p4nB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 2wbeB-4m9dA:
undetectable		 2wbeB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 ILE A 337
LEU A 340
SER A 270
GLN A  10
ILE A 289
 None
 1.27A 2ycjA-4m9dA:
undetectable		 2ycjA-4m9dA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLY A   8
GLY A 221
ALA A  39
VAL A   5
VAL A 225
 None
None
AMP  A 501 ( 4.6A)
None
None
 0.92A 2yvlD-4m9dA:
2.2		 2yvlD-4m9dA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 SER A 327
LEU A 328
GLN A  10
THR A 404
ILE A 406
 None
 1.20A 3a35B-4m9dA:
undetectable		 3a35B-4m9dA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.17A 3dcoB-4m9dA:
undetectable		 3dcoB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.18A 3edlB-4m9dA:
undetectable		 3edlB-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 211
LEU A 207
ARG A 216
PRO A  56
GLY A  58
 None
 1.15A 3iz0B-4m9dA:
undetectable		 3iz0B-4m9dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		3 / 3 ARG A 146
VAL A  67
THR A 203
 None
 0.81A 3k4vD-4m9dA:
undetectable		 3k4vD-4m9dA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 LEU A  86
SER A  92
ILE A  55
CYH A  66
 None
 0.87A 3ko0B-4m9dA:
undetectable		 3ko0B-4m9dA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 LEU A  86
SER A  92
ILE A  55
CYH A  66
 None
 0.86A 3ko0S-4m9dA:
undetectable		 3ko0S-4m9dA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		3 / 3 ARG A 146
VAL A  67
THR A 203
 None
 0.80A 3ndtA-4m9dA:
undetectable		 3ndtA-4m9dA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 5 GLY A 245
ILE A 243
VAL A   5
SER A 321
 None
 1.03A 4d33A-4m9dA:
undetectable		 4d33A-4m9dA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 5 GLY A 245
ILE A 243
VAL A   5
SER A 321
 None
 1.02A 4d33B-4m9dA:
undetectable		 4d33B-4m9dA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 245
ILE A 243
VAL A   5
SER A 321
 None
 1.01A 4d39B-4m9dA:
undetectable		 4d39B-4m9dA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 246
ILE A 243
VAL A   5
SER A 321
 None
 1.08A 4d39B-4m9dA:
undetectable		 4d39B-4m9dA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLU A 295
ILE A 337
GLY A 307
SER A 270
GLN A  10
 None
 1.48A 4djfA-4m9dA:
undetectable		 4djfA-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLU A 295
ILE A 337
GLY A 307
SER A 270
GLN A  10
 None
 1.31A 4djfB-4m9dA:
undetectable		 4djfB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 GLU A 295
ILE A 337
LEU A 340
GLY A 307
SER A 270
 None
 1.37A 4djfB-4m9dA:
undetectable		 4djfB-4m9dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 229
ASN A 241
GLU A  14
VAL A 313
 None
None
MLI  A 502 (-4.7A)
None
 0.99A 4ejwB-4m9dA:
undetectable		 4ejwB-4m9dA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 289
VAL A 333
LYS A 266
LEU A 334
 None
 1.01A 4em2A-4m9dA:
undetectable		 4em2A-4m9dA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 LEU A 360
ASN A 361
LEU A 363
ALA A 364
ARG A 271
 None
 1.32A 4fn9B-4m9dA:
undetectable		 4fn9B-4m9dA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		3 / 3 PRO A  76
TYR A 189
GLY A 193
 None
 0.75A 4g2zA-4m9dA:
undetectable		 4g2zA-4m9dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 245
ILE A 243
VAL A   5
SER A 321
 None
 0.98A 4kcnA-4m9dA:
undetectable		 4kcnA-4m9dA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 GLY A 246
ILE A 243
VAL A   5
SER A 321
 None
 0.99A 4kcnA-4m9dA:
undetectable		 4kcnA-4m9dA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 10 TYR A 268
ASP A  13
GLY A 293
SER A 270
GLY A 307
 None
EDO  A 503 ( 3.3A)
None
None
None
 1.35A 4mmcA-4m9dA:
undetectable		 4mmcA-4m9dA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 9 TYR A 268
ASP A  13
GLY A 293
SER A 270
GLY A 307
 None
EDO  A 503 ( 3.3A)
None
None
None
 1.39A 4mmfA-4m9dA:
undetectable		 4mmfA-4m9dA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 ILE A  19
THR A  20
ARG A 260
LEU A  23
LEU A 218
 None
 1.47A 4pbhA-4m9dA:
undetectable		 4pbhA-4m9dA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 7 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 1.02A 4w5oA-4m9dA:
undetectable		 4w5oA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 1.00A 4w5qA-4m9dA:
undetectable		 4w5qA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 0.99A 4w5tA-4m9dA:
undetectable		 4w5tA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 1.01A 4z4cA-4m9dA:
undetectable		 4z4cA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 1.00A 4z4dA-4m9dA:
undetectable		 4z4dA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 7 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 0.98A 4z4eA-4m9dA:
undetectable		 4z4eA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 7 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 0.97A 4z4gA-4m9dA:
undetectable		 4z4gA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 8 ALA A 222
HIS A  41
ARG A  32
HIS A  53
 None
MLI  A 502 (-4.2A)
None
None
 1.26A 5db5A-4m9dA:
undetectable
5db5B-4m9dA:
undetectable		 5db5A-4m9dA:
22.72
5db5B-4m9dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 12 SER A 240
GLY A  69
GLY A  71
GLY A  35
ASP A 202
 None
 0.87A 5ekxA-4m9dA:
undetectable		 5ekxA-4m9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		3 / 3 GLU A  81
TYR A  85
ARG A  89
 None
 0.80A 5uunB-4m9dA:
undetectable		 5uunB-4m9dA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 9 TYR A 268
ASP A  13
GLY A 293
SER A 270
GLY A 307
 None
EDO  A 503 ( 3.3A)
None
None
None
 1.28A 6awoA-4m9dA:
undetectable		 6awoA-4m9dA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		5 / 9 TYR A 268
ASP A  13
GLY A 293
SER A 270
GLY A 307
 None
EDO  A 503 ( 3.3A)
None
None
None
 1.28A 6awqA-4m9dA:
undetectable		 6awqA-4m9dA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 6 ILE A 132
GLN A 223
ILE A 229
ASP A 228
 AMP  A 501 ( 4.3A)
AMP  A 501 (-4.1A)
None
None
 0.94A 6cbdA-4m9dA:
undetectable		 6cbdA-4m9dA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 4m9d ADENYLOSUCCINATE
SYNTHETASE
(Bacillus
anthracis) 		4 / 8 HIS A  41
GLY A  15
GLY A   8
GLU A 220
 MLI  A 502 (-4.2A)
MLI  A 502 (-3.3A)
None
None
 0.75A 6mdqA-4m9dA:
undetectable		 6mdqA-4m9dA:
11.03