SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4m9q ARF-LIKE GTPASE
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A 176
LEU A 177
LEU A 173
ILE A  39
LEU A  24
 None
 0.95A 2f8dA-4m9qA:
undetectable		 2f8dA-4m9qA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4m9q ARF-LIKE GTPASE
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A 176
LEU A 177
LEU A 173
ILE A  39
LEU A  24
 None
 0.95A 2f8dB-4m9qA:
undetectable		 2f8dB-4m9qA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4m9q ARF-LIKE GTPASE
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A  90
LEU A  24
THR A 183
VAL A  67
PRO A 122
 None
 1.19A 3dcjA-4m9qA:
3.8
3dcjB-4m9qA:
3.6		 3dcjA-4m9qA:
23.60
3dcjB-4m9qA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4m9q ARF-LIKE GTPASE
(Chlamydomonas
reinhardtii) 		4 / 9 ILE A  39
VAL A  91
ASN A 128
ASP A 170
 None
None
GNP  A 301 (-3.3A)
None
 0.98A 5lg3I-4m9qA:
undetectable		 5lg3I-4m9qA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4m9q ARF-LIKE GTPASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  36
ASN A  37
LEU A  35
VAL A 169
LEU A 177
 None
 1.11A 5uc1B-4m9qA:
undetectable		 5uc1B-4m9qA:
15.09