SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7W_A_MTXA301_1 (PTERIDINE REDUCTASE)	4m9r	CELL DEATH PROTEIN 3 (Caenorhabditis elegans)	5 / 12	SER A 307 PRO A 496 LEU A 272 TYR A 278 LEU A 458	None	1.32A	1e7wA-4m9rA: 5.0	1e7wA-4m9rA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IYF_B_ERYB1399_0 (OLEANDOMYCIN GLYCOSYLTRANSFERASE)	4m9r	CELL DEATH PROTEIN 3 (Caenorhabditis elegans)	5 / 12	PHE A 469 ILE A 438 LEU A 272 ALA A 420 ASP A 216	None	1.29A	2iyfB-4m9rA: 3.2	2iyfB-4m9rA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IYF_B_ERYB1399_0 (OLEANDOMYCIN GLYCOSYLTRANSFERASE)	4m9r	CELL DEATH PROTEIN 3 (Caenorhabditis elegans)	5 / 12	VAL A 465 PHE A 469 LEU A 272 ALA A 420 ASP A 216	None	1.23A	2iyfB-4m9rA: 3.2	2iyfB-4m9rA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEY_A_EV1A1771_1 (CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE)	4m9r	CELL DEATH PROTEIN 3 (Caenorhabditis elegans)	6 / 12	LEU A 458 LEU A 416 ILE A 309 TYR A 278 PHE A 273 MET A 276	None	1.02A	2weyA-4m9rA: undetectable	2weyA-4m9rA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OT2_A_ACTA605_0 (SERUM ALBUMIN)	4m9r	CELL DEATH PROTEIN 3 (Caenorhabditis elegans)	3 / 3	LYS A 409 LYS A 351 ALA A 347	None	1.24A	4ot2A-4m9rA: undetectable	4ot2A-4m9rA: 18.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7W_A_MTXA301_1","PTERIDINE REDUCTASE","4m9r","CELL DEATH PROTEIN 3","Caenorhabditis elegans",5,"SER A 307;PRO A 496;LEU A 272;TYR A 278;LEU A 458","None","1.32A","1e7wA-4m9rA:5.0","1e7wA-4m9rA:18.98"],["2IYF_B_ERYB1399_0","OLEANDOMYCIN GLYCOSYLTRANSFERASE","4m9r","CELL DEATH PROTEIN 3","Caenorhabditis elegans",5,"PHE A 469;ILE A 438;LEU A 272;ALA A 420;ASP A 216","None","1.29A","2iyfB-4m9rA:3.2","2iyfB-4m9rA:21.99"],["2IYF_B_ERYB1399_0","OLEANDOMYCIN GLYCOSYLTRANSFERASE","4m9r","CELL DEATH PROTEIN 3","Caenorhabditis elegans",5,"VAL A 465;PHE A 469;LEU A 272;ALA A 420;ASP A 216","None","1.23A","2iyfB-4m9rA:3.2","2iyfB-4m9rA:21.99"],["2WEY_A_EV1A1771_1","CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE","4m9r","CELL DEATH PROTEIN 3","Caenorhabditis elegans",6,"LEU A 458;LEU A 416;ILE A 309;TYR A 278;PHE A 273;MET A 276","None","1.02A","2weyA-4m9rA:undetectable","2weyA-4m9rA:19.24"],["4OT2_A_ACTA605_0","SERUM ALBUMIN","4m9r","CELL DEATH PROTEIN 3","Caenorhabditis elegans",3,"LYS A 409;LYS A 351;ALA A 347","None","1.24A","4ot2A-4m9rA:undetectable","4ot2A-4m9rA:18.78"]]