SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4maf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 5 SER A 226
THR A 228
GLU A  95
GLY A  96
 None
 1.34A 1icrA-4mafA:
undetectable
1icrB-4mafA:
undetectable		 1icrA-4mafA:
20.00
1icrB-4mafA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 5 GLU A  95
GLY A  96
SER A 226
THR A 228
 None
 1.31A 1icrA-4mafA:
undetectable
1icrB-4mafA:
undetectable		 1icrA-4mafA:
20.00
1icrB-4mafA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 5 GLU A  95
GLY A  96
SER A 226
THR A 228
 None
 1.32A 1kqbA-4mafA:
undetectable
1kqbB-4mafA:
undetectable		 1kqbA-4mafA:
21.17
1kqbB-4mafA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4maf ATP SULFURYLASE
(Glycine
max) 		3 / 3 ALA A 287
VAL A 290
TRP A 294
 None
 0.79A 1tkqA-4mafA:
undetectable		 1tkqA-4mafA:
2.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 6 LEU A  93
LEU A  60
LEU A 164
LEU A  82
 None
 0.91A 2ab2A-4mafA:
undetectable		 2ab2A-4mafA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 4 ALA A 244
VAL A 347
PHE A 245
THR A 262
 None
ADX  A 900 (-4.1A)
ADX  A 900 (-4.4A)
None
 1.42A 2pkkA-4mafA:
undetectable		 2pkkA-4mafA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 4maf ATP SULFURYLASE
(Glycine
max) 		5 / 12 SER A 130
ASN A 128
GLY A 369
ASP A 350
PHE A 245
 None
None
None
None
ADX  A 900 (-4.4A)
 1.28A 3a25A-4mafA:
undetectable		 3a25A-4mafA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 8 LEU A 281
GLY A 283
HIS A 323
TYR A 324
 None
 0.91A 3af0A-4mafA:
undetectable		 3af0A-4mafA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		5 / 12 LEU A 189
LEU A 363
MET A 354
ILE A 196
PRO A 327
 None
 1.31A 3aqiB-4mafA:
undetectable		 3aqiB-4mafA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		3 / 3 SER A 414
GLY A 415
THR A 416
 None
 0.09A 3k9wA-4mafA:
9.7		 3k9wA-4mafA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4maf ATP SULFURYLASE
(Glycine
max) 		5 / 12 LEU A 189
LEU A 363
MET A 354
ILE A 196
PRO A 327
 None
 1.30A 3w1wA-4mafA:
3.3		 3w1wA-4mafA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4maf ATP SULFURYLASE
(Glycine
max) 		3 / 3 TYR A 364
ARG A 361
HIS A 356
 None
 0.73A 4fubA-4mafA:
undetectable		 4fubA-4mafA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 4 LEU A  49
ARG A 381
ILE A  50
ILE A 338
 None
 1.29A 5dzk2-4mafA:
undetectable
5dzkM-4mafA:
undetectable
5dzkN-4mafA:
undetectable		 5dzk2-4mafA:
20.00
5dzkM-4mafA:
21.46
5dzkN-4mafA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4maf ATP SULFURYLASE
(Glycine
max) 		4 / 4 ILE A 178
ILE A 196
ARG A 177
LEU A 189
 None
 1.29A 5dzkh-4mafA:
undetectable
5dzkn-4mafA:
undetectable
5dzkv-4mafA:
undetectable		 5dzkh-4mafA:
21.46
5dzkn-4mafA:
21.46
5dzkv-4mafA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4maf ATP SULFURYLASE
(Glycine
max) 		3 / 3 LYS A 335
ASN A 128
SER A 130
 None
 1.25A 5yw0A-4mafA:
undetectable		 5yw0A-4mafA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 4maf ATP SULFURYLASE
(Glycine
max) 		5 / 12 ILE A 338
LEU A  49
VAL A 242
LEU A 379
LEU A 373
 None
 1.22A 6b54A-4mafA:
undetectable		 6b54A-4mafA:
18.70