SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_G_PZIG801_0 (GLUTAMATE RECEPTOR 2)	4mah	AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE (Aspergillus oryzae)	3 / 3	PRO A 51 SER A 53 ASN A 42	None	0.81A	3lslG-4mahA: undetectable	3lslG-4mahA: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GBO_A_CUA301_0 (E7)	4mah	AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE (Aspergillus oryzae)	4 / 5	HIS A 1 ALA A 58 HIS A 60 TYR A 140	ZN A 301 (-3.1A) ZN A 301 ( 3.9A) ZN A 301 (-3.2A) None	0.57A	4gboA-4mahA: 9.3	4gboA-4mahA: 23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KF8_A_GCSA404_1 (PREDICTED ACETYLTRANSFERASE)	4mah	AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE (Aspergillus oryzae)	4 / 8	ARG A 191 GLU A 88 GLY A 196 PRO A 195	None	1.11A	5kf8A-4mahA: undetectable	5kf8A-4mahA: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UIZ_A_CUA301_0 (AA10A)	4mah	AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE (Aspergillus oryzae)	4 / 5	HIS A 1 ALA A 58 HIS A 60 TYR A 140	ZN A 301 (-3.1A) ZN A 301 ( 3.9A) ZN A 301 (-3.2A) None	0.56A	5uizA-4mahA: 9.3	5uizA-4mahA: 23.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LSL_G_PZIG801_0","GLUTAMATE RECEPTOR 2","4mah","AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE","Aspergillus oryzae",3,"PRO A  51;SER A  53;ASN A  42","None","0.81A","3lslG-4mahA:undetectable","3lslG-4mahA:21.93"],["4GBO_A_CUA301_0","E7","4mah","AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE","Aspergillus oryzae",4,"HIS A   1;ALA A  58;HIS A  60;TYR A 140"," ZN A 301 (-3.1A); ZN A 301 ( 3.9A); ZN A 301 (-3.2A);None","0.57A","4gboA-4mahA:9.3","4gboA-4mahA:23.36"],["5KF8_A_GCSA404_1","PREDICTED ACETYLTRANSFERASE","4mah","AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE","Aspergillus oryzae",4,"ARG A 191;GLU A  88;GLY A 196;PRO A 195","None","1.11A","5kf8A-4mahA:undetectable","5kf8A-4mahA:19.60"],["5UIZ_A_CUA301_0","AA10A","4mah","AA11 LYTIC POLYSACCHARIDE MONOOXYGENASE","Aspergillus oryzae",4,"HIS A   1;ALA A  58;HIS A  60;TYR A 140"," ZN A 301 (-3.1A); ZN A 301 ( 3.9A); ZN A 301 (-3.2A);None","0.56A","5uizA-4mahA:9.3","5uizA-4mahA:23.36"]]