SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4maq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_B_PFLB4002_1 (SERUM ALBUMIN)	4maq	PUTATIVE FUMARYLPYRUVATE HYDROLASE (Burkholderia cenocepacia)	4 / 6	PHE A 198 LEU A 112 VAL A 68 VAL A 140	None	1.04A	1e7aB-4maqA: undetectable	1e7aB-4maqA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_B_SAMB201_1 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	4maq	PUTATIVE FUMARYLPYRUVATE HYDROLASE (Burkholderia cenocepacia)	4 / 5	PRO A 210 ALA A 230 ASP A 212 ASP A 164	None	1.08A	2nyuB-4maqA: undetectable	2nyuB-4maqA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4maq	PUTATIVE FUMARYLPYRUVATE HYDROLASE (Burkholderia cenocepacia)	5 / 12	LEU A 83 GLY A 217 ALA A 222 PHE A 224 PHE A 226	None	1.03A	4hytA-4maqA: undetectable	4hytA-4maqA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_C_OBNC2004_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4maq	PUTATIVE FUMARYLPYRUVATE HYDROLASE (Burkholderia cenocepacia)	5 / 12	LEU A 83 GLY A 217 ALA A 222 PHE A 224 PHE A 226	None	1.05A	4hytC-4maqA: undetectable	4hytC-4maqA: 13.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7A_B_PFLB4002_1","SERUM ALBUMIN","4maq","PUTATIVE FUMARYLPYRUVATE HYDROLASE","Burkholderia cenocepacia",4,"PHE A 198;LEU A 112;VAL A  68;VAL A 140","None","1.04A","1e7aB-4maqA:undetectable","1e7aB-4maqA:17.39"],["2NYU_B_SAMB201_1","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","4maq","PUTATIVE FUMARYLPYRUVATE HYDROLASE","Burkholderia cenocepacia",4,"PRO A 210;ALA A 230;ASP A 212;ASP A 164","None","1.08A","2nyuB-4maqA:undetectable","2nyuB-4maqA:22.76"],["4HYT_A_OBNA1104_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","4maq","PUTATIVE FUMARYLPYRUVATE HYDROLASE","Burkholderia cenocepacia",5,"LEU A  83;GLY A 217;ALA A 222;PHE A 224;PHE A 226","None","1.03A","4hytA-4maqA:undetectable","4hytA-4maqA:13.73"],["4HYT_C_OBNC2004_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","4maq","PUTATIVE FUMARYLPYRUVATE HYDROLASE","Burkholderia cenocepacia",5,"LEU A  83;GLY A 217;ALA A 222;PHE A 224;PHE A 226","None","1.05A","4hytC-4maqA:undetectable","4hytC-4maqA:13.73"]]