SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4max'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_K_FUAK712_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4max	CYANOGLOBIN (Synechococcus sp. PCC 7002)	3 / 3	VAL A 108 ALA A 54 HIS A 117	None None HEB A 201 (-2.6A)	0.79A	1q23L-4maxA: undetectable	1q23L-4maxA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_B_GLYB709_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	4max	CYANOGLOBIN (Synechococcus sp. PCC 7002)	4 / 5	GLY A 63 ASP A 120 ARG A 64 ARG A 67	None	1.35A	6dwdB-4maxA: undetectable 6dwdD-4maxA: undetectable	6dwdB-4maxA: 14.45 6dwdD-4maxA: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWJ_B_GLYB710_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	4max	CYANOGLOBIN (Synechococcus sp. PCC 7002)	4 / 5	ARG A 64 ARG A 67 GLY A 63 ASP A 120	None	1.34A	6dwjB-4maxA: undetectable 6dwjD-4maxA: 2.2	6dwjB-4maxA: 14.45 6dwjD-4maxA: 14.45