SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		6 / 11 LEU A 137
ASP A 141
ILE A   7
GLY A 180
PRO A 179
HIS A  69
 None
None
None
None
None
SO4  A 304 (-3.9A)
 1.46A 1s9aA-4mb7A:
undetectable		 1s9aA-4mb7A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		6 / 12 LEU A 137
ASP A 141
ILE A   7
GLY A 180
PRO A 179
HIS A  69
 None
None
None
None
None
SO4  A 304 (-3.9A)
 1.41A 1s9aB-4mb7A:
undetectable		 1s9aB-4mb7A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 4 LEU A 100
VAL A  99
ILE A  98
TRP A  45
 None
 1.26A 1s9qB-4mb7A:
undetectable		 1s9qB-4mb7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 7 MET A  70
ILE A   7
LYS A  13
TYR A  53
 None
None
SO4  A 302 (-2.9A)
None
 0.90A 3eteD-4mb7A:
undetectable
3eteF-4mb7A:
undetectable		 3eteD-4mb7A:
21.28
3eteF-4mb7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 LEU A 137
ILE A   7
GLY A 180
PRO A 179
HIS A  69
 None
None
None
None
SO4  A 304 (-3.9A)
 1.33A 3hgiA-4mb7A:
undetectable		 3hgiA-4mb7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 7 TYR A 103
THR A  85
ILE A  91
GLY A  79
 None
 0.66A 4eq4A-4mb7A:
undetectable		 4eq4A-4mb7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 7 TYR A 103
THR A  85
ILE A  91
GLY A  79
 None
 0.67A 4eqlA-4mb7A:
undetectable		 4eqlA-4mb7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 7 TYR A 103
THR A  85
ILE A  91
GLY A  79
 None
 0.66A 4eqlB-4mb7A:
undetectable		 4eqlB-4mb7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 7 TYR A 103
THR A  85
ILE A  91
GLY A  79
 None
 0.71A 4l39B-4mb7A:
undetectable		 4l39B-4mb7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 5 LYS A  61
PRO A  62
LEU A  37
TYR A  40
 None
 1.50A 4w5qA-4mb7A:
undetectable		 4w5qA-4mb7A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4mb7 ENDONUCLEASE 8-LIKE
L720
(Acanthamoeba
polyphaga
mimivirus) 		4 / 8 ILE A  92
ILE A  76
THR A  10
TYR A  11
 None
 0.89A 6cduG-4mb7A:
undetectable
6cduH-4mb7A:
undetectable		 6cduG-4mb7A:
22.94
6cduH-4mb7A:
22.94