SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mb8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4mb8 URICASE
(unclassified
Mammalia) 		4 / 6 ILE A 276
GLU A 280
LYS A 278
ASN A 267
 None
 1.44A 3kp6A-4mb8A:
undetectable
3kp6B-4mb8A:
undetectable		 3kp6A-4mb8A:
19.87
3kp6B-4mb8A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4mb8 URICASE
(unclassified
Mammalia) 		3 / 3 HIS A 104
SER A  53
LYS A  55
 None
 1.49A 5os7A-4mb8A:
undetectable		 5os7A-4mb8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4mb8 URICASE
(unclassified
Mammalia) 		3 / 3 HIS A 104
SER A  53
LYS A  55
 None
 1.49A 6gmdB-4mb8A:
undetectable		 6gmdB-4mb8A:
21.75