SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 PHE A  70
HIS A 137
LEU A 141
THR A 140
 None
CD  A 204 ( 3.6A)
None
None
 1.05A 1azmA-4mbuA:
undetectable		 1azmA-4mbuA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 5 GLU A 158
ARG A 113
THR A 114
ASP A 160
 None
 1.36A 4e7cA-4mbuA:
undetectable
4e7cB-4mbuA:
undetectable		 4e7cA-4mbuA:
17.10
4e7cB-4mbuA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 PHE A  70
VAL A 116
GLU A 158
 None
 0.70A 4fvqA-4mbuA:
undetectable		 4fvqA-4mbuA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ALA A  12
ASN A  -1
GLY A  59
SER A  89
 None
 0.83A 4r20A-4mbuA:
undetectable		 4r20A-4mbuA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ALA A 155
LEU A 154
ALA A 125
ILE A 127
ILE A  84
 None
 1.02A 4r3aB-4mbuA:
undetectable		 4r3aB-4mbuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 GLU A  56
ILE A   2
LEU A 129
ILE A  95
 None
 0.84A 4xumA-4mbuA:
undetectable		 4xumA-4mbuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4mbu SIMILAR TO
N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 GLU A  37
TRP A  41
ASN A  18
 None
 1.15A 5dv4A-4mbuA:
undetectable		 5dv4A-4mbuA:
18.51