SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ILE A  83
SER A 110
LEU A  61
GLU A  85
 None
 0.96A 2cdqA-4mc5A:
undetectable		 2cdqA-4mc5A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 GLY A 247
GLY A 198
VAL A 129
LEU A 162
 None
 0.81A 2oa1B-4mc5A:
undetectable		 2oa1B-4mc5A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 LEU A 175
PHE A 258
LEU A 105
GLN A 239
SER A 101
 None
 1.34A 2qd4A-4mc5A:
undetectable		 2qd4A-4mc5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 SER A 394
SER A 110
LEU A 105
ASP A 104
 None
 0.94A 3m0wE-4mc5A:
0.8
3m0wF-4mc5A:
0.8
3m0wG-4mc5A:
undetectable
3m0wH-4mc5A:
0.8		 3m0wE-4mc5A:
10.74
3m0wF-4mc5A:
10.74
3m0wG-4mc5A:
10.74
3m0wH-4mc5A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 LYS A  51
GLU A  79
TRP A  80
 None
 1.20A 3v4tH-4mc5A:
undetectable		 3v4tH-4mc5A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 ASP A  98
GLU A 103
SER A 219
 None
 0.86A 5bw4B-4mc5A:
undetectable		 5bw4B-4mc5A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 LEU A 175
TYR A 148
PRO A 252
ILE A 120
 None
 1.31A 5esgA-4mc5A:
undetectable		 5esgA-4mc5A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4mc5 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 GLY A 465
ASN A 464
MET A 462
ILE A   7
 None
 0.99A 5j4nA-4mc5A:
undetectable		 5j4nA-4mc5A:
21.37