SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_F_9PLF1_1 (CYTOCHROME P450 2A13)	4mck	CHITINASE (Zea mays)	4 / 8	PHE A 39 PHE A 6 PHE A 56 ALA A 57	None	0.94A	3t3sF-4mckA: undetectable	3t3sF-4mckA: 17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CLA_A_CLMA221_0 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	4mck	CHITINASE (Zea mays)	5 / 11	THR A 136 ALA A 137 PHE A 55 PHE A 23 ILE A 69	None	1.17A	4claA-4mckA: undetectable	4claA-4mckA: 20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYQ_A_3CJA607_1 (LACTOPEROXIDASE)	4mck	CHITINASE (Zea mays)	3 / 3	GLN A 173 HIS A 61 ARG A 177	None	1.27A	4qyqA-4mckA: undetectable	4qyqA-4mckA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYQ_B_3CJB607_1 (LACTOPEROXIDASE)	4mck	CHITINASE (Zea mays)	3 / 3	GLN A 173 HIS A 61 ARG A 177	None	1.21A	4qyqB-4mckA: undetectable	4qyqB-4mckA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I71_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	4mck	CHITINASE (Zea mays)	5 / 12	ILE A 52 ALA A 53 GLY A 38 PHE A 39 VAL A 33	None	1.25A	5i71A-4mckA: undetectable	5i71A-4mckA: 15.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3T3S_F_9PLF1_1","CYTOCHROME P450 2A13","4mck","CHITINASE","Zea mays",4,"PHE A  39;PHE A   6;PHE A  56;ALA A  57","None","0.94A","3t3sF-4mckA:undetectable","3t3sF-4mckA:17.41"],["4CLA_A_CLMA221_0","TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE","4mck","CHITINASE","Zea mays",5,"THR A 136;ALA A 137;PHE A  55;PHE A  23;ILE A  69","None","1.17A","4claA-4mckA:undetectable","4claA-4mckA:20.49"],["4QYQ_A_3CJA607_1","LACTOPEROXIDASE","4mck","CHITINASE","Zea mays",3,"GLN A 173;HIS A  61;ARG A 177","None","1.27A","4qyqA-4mckA:undetectable","4qyqA-4mckA:16.55"],["4QYQ_B_3CJB607_1","LACTOPEROXIDASE","4mck","CHITINASE","Zea mays",3,"GLN A 173;HIS A  61;ARG A 177","None","1.21A","4qyqB-4mckA:undetectable","4qyqB-4mckA:16.55"],["5I71_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","4mck","CHITINASE","Zea mays",5,"ILE A  52;ALA A  53;GLY A  38;PHE A  39;VAL A  33","None","1.25A","5i71A-4mckA:undetectable","5i71A-4mckA:15.22"]]