SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mdc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_C_SAMC301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4mdc	PUTATIVE GLUTATHIONE S-TRANSFERASE (Sinorhizobium meliloti)	5 / 12	ARG A 215 GLY A 185 ILE A 145 ARG A 14 LEU A 181	None	1.32A	3iv6C-4mdcA: undetectable	3iv6C-4mdcA: 23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1476_0 (MJ0495-LIKE PROTEIN)	4mdc	PUTATIVE GLUTATHIONE S-TRANSFERASE (Sinorhizobium meliloti)	4 / 5	ILE A 178 ALA A 195 HIS A 148 MET A 149	None	1.11A	4ac9B-4mdcA: undetectable 4ac9C-4mdcA: undetectable	4ac9B-4mdcA: 20.50 4ac9C-4mdcA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1476_0 (TRANSLATION ELONGATION FACTOR SELB)	4mdc	PUTATIVE GLUTATHIONE S-TRANSFERASE (Sinorhizobium meliloti)	4 / 5	ILE A 178 ALA A 195 HIS A 148 MET A 149	None	1.15A	4acaB-4mdcA: undetectable 4acaC-4mdcA: undetectable	4acaB-4mdcA: 20.50 4acaC-4mdcA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QCK_A_ASDA404_1 (3-KETOSTEROID-9-ALPH A-MONOOXYGENASE OXYGENASE SUBUNIT)	4mdc	PUTATIVE GLUTATHIONE S-TRANSFERASE (Sinorhizobium meliloti)	5 / 12	HIS A 224 ALA A 192 MET A 149 GLY A 185 ASP A 182	None	1.26A	4qckA-4mdcA: undetectable	4qckA-4mdcA: 18.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IV6_C_SAMC301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4mdc","PUTATIVE GLUTATHIONE S-TRANSFERASE","Sinorhizobium meliloti",5,"ARG A 215;GLY A 185;ILE A 145;ARG A  14;LEU A 181","None","1.32A","3iv6C-4mdcA:undetectable","3iv6C-4mdcA:23.93"],["4AC9_C_DXCC1476_0","MJ0495-LIKE PROTEIN","4mdc","PUTATIVE GLUTATHIONE S-TRANSFERASE","Sinorhizobium meliloti",4,"ILE A 178;ALA A 195;HIS A 148;MET A 149","None","1.11A","4ac9B-4mdcA:undetectable;4ac9C-4mdcA:undetectable","4ac9B-4mdcA:20.50;4ac9C-4mdcA:20.50"],["4ACA_C_DXCC1476_0","TRANSLATION ELONGATION FACTOR SELB","4mdc","PUTATIVE GLUTATHIONE S-TRANSFERASE","Sinorhizobium meliloti",4,"ILE A 178;ALA A 195;HIS A 148;MET A 149","None","1.15A","4acaB-4mdcA:undetectable;4acaC-4mdcA:undetectable","4acaB-4mdcA:20.50;4acaC-4mdcA:20.50"],["4QCK_A_ASDA404_1","3-KETOSTEROID-9-ALPHA-MONOOXYGENASE OXYGENASE SUBUNIT","4mdc","PUTATIVE GLUTATHIONE S-TRANSFERASE","Sinorhizobium meliloti",5,"HIS A 224;ALA A 192;MET A 149;GLY A 185;ASP A 182","None","1.26A","4qckA-4mdcA:undetectable","4qckA-4mdcA:18.67"]]