SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mdw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 1v54N-4mdwA:
undetectable
1v54P-4mdwA:
undetectable		 1v54N-4mdwA:
14.34
1v54P-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 2dyrA-4mdwA:
undetectable
2dyrC-4mdwA:
undetectable		 2dyrA-4mdwA:
14.34
2dyrC-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 2eijN-4mdwA:
undetectable
2eijP-4mdwA:
undetectable		 2eijN-4mdwA:
14.34
2eijP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 2eikA-4mdwA:
undetectable
2eikC-4mdwA:
undetectable		 2eikA-4mdwA:
14.34
2eikC-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 2eikN-4mdwA:
undetectable
2eikP-4mdwA:
undetectable		 2eikN-4mdwA:
14.34
2eikP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 2eilN-4mdwA:
undetectable
2eilP-4mdwA:
undetectable		 2eilN-4mdwA:
14.34
2eilP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 3abkN-4mdwA:
undetectable
3abkP-4mdwA:
undetectable		 3abkN-4mdwA:
14.34
3abkP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 3ag1A-4mdwA:
undetectable
3ag1C-4mdwA:
undetectable		 3ag1A-4mdwA:
14.34
3ag1C-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 3ag1N-4mdwA:
undetectable
3ag1P-4mdwA:
undetectable		 3ag1N-4mdwA:
14.34
3ag1P-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 5b1bN-4mdwA:
undetectable
5b1bP-4mdwA:
undetectable		 5b1bN-4mdwA:
14.34
5b1bP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 5b3sN-4mdwA:
undetectable
5b3sP-4mdwA:
undetectable		 5b3sN-4mdwA:
14.34
5b3sP-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		3 / 3 LYS A 132
HIS A 130
HIS A 158
 MLY  A 131 ( 3.6A)
MLY  A 131 ( 3.7A)
None
 1.22A 5oexA-4mdwA:
undetectable		 5oexA-4mdwA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 5x19N-4mdwA:
undetectable
5x19P-4mdwA:
undetectable		 5x19N-4mdwA:
14.34
5x19P-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 6nknA-4mdwA:
undetectable
6nknC-4mdwA:
undetectable		 6nknA-4mdwA:
14.34
6nknC-4mdwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mdw UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 6nmfN-4mdwA:
undetectable
6nmfP-4mdwA:
undetectable		 6nmfN-4mdwA:
14.34
6nmfP-4mdwA:
19.69