SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4me2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		5 / 11 ALA A  52
LEU A  77
LEU A  56
SER A  99
ALA A 101
 None
 1.17A 1h9zA-4me2A:
undetectable		 1h9zA-4me2A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		5 / 12 LEU A  80
ALA A 104
ALA A  73
LEU A  56
LEU A  86
 None
 1.13A 3p5nA-4me2A:
undetectable		 3p5nA-4me2A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		5 / 12 LEU A  80
ALA A 104
ALA A  73
LEU A  56
LEU A  86
 None
 1.12A 3p5nB-4me2A:
undetectable		 3p5nB-4me2A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		3 / 3 PHE A 124
SER A 127
GLN A  93
 None
 0.74A 3smtA-4me2A:
undetectable		 3smtA-4me2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		4 / 5 ARG A 183
LEU A 178
VAL A 125
ASP A 140
 None
 1.13A 3ufnA-4me2A:
undetectable
3ufnB-4me2A:
undetectable		 3ufnA-4me2A:
14.06
3ufnB-4me2A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		3 / 3 ARG A 189
ARG A 185
ILE A 147
 None
 0.86A 4b7qC-4me2A:
undetectable		 4b7qC-4me2A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4me2 UNCHARACTERIZED
PROTEIN
(Brachypodium
distachyon) 		4 / 4 ALA A 136
VAL A 139
ASP A 140
LEU A 178
 None
 0.98A 4e7gA-4me2A:
undetectable		 4e7gA-4me2A:
22.30