SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4me9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		4 / 8 LYS A 116
SER A 115
PHE A  56
ASP A 107
 None
 1.19A 1rg9B-4me9A:
undetectable		 1rg9B-4me9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		4 / 8 LYS A 116
SER A 115
PHE A  56
ASP A 107
 None
 1.20A 1rg9C-4me9A:
undetectable		 1rg9C-4me9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		4 / 8 LYS A 116
SER A 115
PHE A  56
ASP A 107
 None
 1.17A 1rg9D-4me9A:
undetectable		 1rg9D-4me9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		4 / 5 PRO A  28
ALA A  31
ALA A  38
ILE A  41
 None
 0.71A 5jncD-4me9A:
undetectable		 5jncD-4me9A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		5 / 7 PHE A  71
ILE A  67
PHE A  99
LEU A  88
ILE A  77
 None
 1.30A 6b5vA-4me9A:
undetectable
6b5vC-4me9A:
undetectable		 6b5vA-4me9A:
16.93
6b5vC-4me9A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		5 / 7 PHE A  71
ILE A  67
PHE A  99
LEU A  88
ILE A  77
 None
 1.30A 6b5vC-4me9A:
undetectable
6b5vD-4me9A:
undetectable		 6b5vC-4me9A:
16.93
6b5vD-4me9A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4me9 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Bacillus
cereus) 		5 / 7 PHE A  71
ILE A  67
PHE A  99
LEU A  88
ILE A  77
 None
 1.30A 6b5vB-4me9A:
undetectable
6b5vD-4me9A:
undetectable		 6b5vB-4me9A:
16.93
6b5vD-4me9A:
16.93