SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		4 / 4 GLY A1086
TYR A1085
GLY A1052
ASP A1037
 None
 0.87A 3kl3A-4meeA:
undetectable		 3kl3A-4meeA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		3 / 3 HIS A1271
SER A1240
ASN A1274
 None
 0.73A 3s8pB-4meeA:
undetectable		 3s8pB-4meeA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		4 / 7 PRO A 965
GLY A1115
VAL A1113
SER A 969
 None
 0.97A 4a3uB-4meeA:
undetectable		 4a3uB-4meeA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		5 / 10 ILE A1187
ALA A1161
GLY A1192
ASN A1218
HIS A1221
 None
 1.40A 4e47D-4meeA:
0.6		 4e47D-4meeA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		5 / 12 ASP A 984
VAL A1162
ALA A1161
GLY A1133
THR A1129
 None
 1.28A 4mm4A-4meeA:
undetectable		 4mm4A-4meeA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		4 / 7 GLU A1152
THR A1150
GLY A1151
THR A1144
 None
 0.99A 4qwpB-4meeA:
undetectable		 4qwpB-4meeA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		3 / 3 ASN A1094
PHE A1099
TYR A1136
 None
 0.89A 4u15A-4meeA:
undetectable		 4u15A-4meeA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		3 / 3 HIS A1271
SER A1240
ASN A1274
 None
 0.66A 5cprB-4meeA:
undetectable		 5cprB-4meeA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		4 / 8 SER A1238
THR A1027
SER A1014
THR A1025
 None
 0.91A 5l4eA-4meeA:
undetectable
5l4eB-4meeA:
undetectable
5l4eC-4meeA:
undetectable
5l4eD-4meeA:
undetectable
5l4eE-4meeA:
undetectable		 5l4eA-4meeA:
20.38
5l4eB-4meeA:
20.38
5l4eC-4meeA:
20.38
5l4eD-4meeA:
20.38
5l4eE-4meeA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4mee DIFFUSE ADHERENCE
ADHESIN
(Escherichia
coli) 		4 / 6 ASP A 984
ARG A1008
GLN A1160
GLN A1267
 None
 1.24A 6g31B-4meeA:
undetectable		 6g31B-4meeA:
11.74