SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.34A 1nncA-4melA:
undetectable		 1nncA-4melA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 2cmlA-4melA:
undetectable		 2cmlA-4melA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.36A 2cmlB-4melA:
undetectable		 2cmlB-4melA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.34A 2cmlC-4melA:
undetectable		 2cmlC-4melA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.38A 2cmlD-4melA:
undetectable		 2cmlD-4melA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		3 / 3 ASN A  44
TYR A 122
SER A  37
 None
 0.69A 2gvcB-4melA:
undetectable		 2gvcB-4melA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		3 / 3 ASN A  44
TYR A 122
SER A  37
 None
 0.70A 2gvcE-4melA:
undetectable		 2gvcE-4melA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.28A 2htqA-4melA:
undetectable		 2htqA-4melA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 3b7eA-4melA:
undetectable		 3b7eA-4melA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 3b7eB-4melA:
undetectable		 3b7eB-4melA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.46A 3k37A-4melA:
undetectable		 3k37A-4melA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.48A 3k39A-4melA:
undetectable		 3k39A-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.45A 3k39E-4melA:
undetectable		 3k39E-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.45A 3k39F-4melA:
undetectable		 3k39F-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.45A 3k39G-4melA:
undetectable		 3k39G-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.46A 3k39H-4melA:
undetectable		 3k39H-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.47A 3k39M-4melA:
undetectable		 3k39M-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.45A 3k39N-4melA:
undetectable		 3k39N-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.45A 3k39P-4melA:
undetectable		 3k39P-4melA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.33A 3sanA-4melA:
undetectable		 3sanA-4melA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 3sanB-4melA:
undetectable		 3sanB-4melA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.31A 3ti5A-4melA:
undetectable		 3ti5A-4melA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.31A 3ti5B-4melA:
undetectable		 3ti5B-4melA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 3ticA-4melA:
undetectable		 3ticA-4melA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 3ticB-4melA:
undetectable		 3ticB-4melA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.33A 3ticC-4melA:
undetectable		 3ticC-4melA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.33A 3ticD-4melA:
undetectable		 3ticD-4melA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.30A 4b7nA-4melA:
undetectable		 4b7nA-4melA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.23A 4b7qA-4melA:
undetectable		 4b7qA-4melA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.23A 4b7qB-4melA:
undetectable		 4b7qB-4melA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 4b7qC-4melA:
undetectable		 4b7qC-4melA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.32A 4b7qD-4melA:
undetectable		 4b7qD-4melA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.34A 4mwrA-4melA:
undetectable		 4mwrA-4melA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.41A 4wa5A-4melA:
undetectable		 4wa5A-4melA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 GLU A  71
GLU A  50
GLU A  43
ARG A  49
TYR A  67
 None
 1.38A 5l17A-4melA:
undetectable		 5l17A-4melA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens) 		5 / 12 ALA A 201
GLU A 155
ARG A 188
VAL A 181
PHE A 172
 None
 1.39A 5vlmE-4melA:
undetectable		 5vlmE-4melA:
23.27