SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4mem UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Rattus
norvegicus) 		4 / 6 TYR A 104
VAL A 132
ILE A 133
LEU A  94
 None
 1.25A 1j96A-4memA:
undetectable		 1j96A-4memA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 4mem UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Rattus
norvegicus) 		4 / 8 SER A 169
LEU A 172
ASP A 171
GLN A 207
 None
 1.06A 4umjA-4memA:
undetectable		 4umjA-4memA:
21.19