SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA502_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 PHE A 322
PHE A 162
GLN A 163
LEU A 190
ILE A 151
 None
None
MG  A 404 ( 4.3A)
None
None
 1.20A 1oltA-4mggA:
undetectable		 1oltA-4mggA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		3 / 3 TRP A 295
THR A 320
TYR A 136
 None
 1.21A 2a3aA-4mggA:
5.1		 2a3aA-4mggA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		3 / 3 TRP A 295
THR A 320
TYR A 136
 None
 1.18A 2a3aB-4mggA:
5.9		 2a3aB-4mggA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		3 / 3 TRP A 295
THR A 320
TYR A 136
 None
 1.21A 2a3bA-4mggA:
5.3		 2a3bA-4mggA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 ALA A 108
PRO A 354
GLY A 351
LEU A 347
ASP A 111
 None
 1.31A 2nv4A-4mggA:
undetectable		 2nv4A-4mggA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 ALA A 284
PRO A 312
GLY A 126
LEU A 125
ASP A 280
 None
 1.15A 2nv4B-4mggA:
undetectable		 2nv4B-4mggA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 6 THR A 180
LEU A 164
VAL A 166
VAL A 210
VAL A 206
 None
 1.27A 2z97A-4mggA:
undetectable		 2z97A-4mggA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 CYH A  50
ALA A 303
ALA A 275
VAL A 269
LEU A  53
 None
 1.28A 3b0wA-4mggA:
undetectable		 3b0wA-4mggA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 CYH A  50
ALA A 303
ALA A 275
VAL A 269
LEU A  53
 None
 1.25A 3b0wB-4mggA:
undetectable		 3b0wB-4mggA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 10 ILE A 291
ILE A 304
VAL A 300
VAL A 269
LEU A 125
 None
 1.10A 3elzC-4mggA:
undetectable		 3elzC-4mggA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 GLU A  49
LEU A  13
VAL A 358
LEU A 359
ALA A 331
 None
 1.45A 3unaA-4mggA:
undetectable		 3unaA-4mggA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 GLU A  49
LEU A  13
VAL A 358
LEU A 359
ALA A 331
 None
 1.45A 3unaB-4mggA:
1.8		 3unaB-4mggA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 GLU A  49
LEU A  13
VAL A 358
LEU A 359
ALA A 331
 None
 1.45A 3uncA-4mggA:
undetectable		 3uncA-4mggA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 GLU A  49
LEU A  13
VAL A 358
LEU A 359
ALA A 331
 None
 1.45A 3uncB-4mggA:
0.7		 3uncB-4mggA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 7 VAL A  28
TYR A 325
TYR A  20
LEU A  53
 None
 0.89A 4b3qA-4mggA:
undetectable		 4b3qA-4mggA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 GLY A 167
GLY A 168
ALA A 192
VAL A 206
VAL A 210
 None
 0.94A 4htfA-4mggA:
2.8		 4htfA-4mggA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 GLY A 167
GLY A 168
ALA A 192
VAL A 206
VAL A 210
 None
 0.90A 4htfB-4mggA:
undetectable		 4htfB-4mggA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 10 LEU A 236
ALA A 192
ILE A 174
THR A 234
ILE A 217
 None
 0.95A 4njuB-4mggA:
undetectable		 4njuB-4mggA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 10 LEU A 236
ALA A 192
ILE A 174
THR A 234
ILE A 217
 None
 0.95A 4njuD-4mggA:
undetectable		 4njuD-4mggA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 LEU A 112
GLY A  46
ILE A  87
MET A  91
LEU A  76
 None
 1.26A 4x3mB-4mggA:
undetectable		 4x3mB-4mggA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 6 ARG A 205
ASP A 172
GLY A 168
ASP A 169
 None
 1.50A 5hp1C-4mggA:
undetectable		 5hp1C-4mggA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 ALA A 334
LEU A  13
SER A  33
LEU A 121
ILE A 266
 None
 1.18A 5hv1A-4mggA:
3.7		 5hv1A-4mggA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 ASP A 106
ALA A 275
LEU A 307
ASN A  88
GLY A  85
 None
 1.01A 5kb5A-4mggA:
undetectable		 5kb5A-4mggA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 GLU A 332
GLY A 333
VAL A  11
LEU A  13
ILE A 355
 None
 1.17A 5vooE-4mggA:
6.9		 5vooE-4mggA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 9 THR A 353
ALA A 331
GLY A 351
LEU A 347
SER A 345
 None
 1.17A 5vw4A-4mggA:
undetectable		 5vw4A-4mggA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 8 ARG A 232
THR A 234
ILE A 217
PRO A 220
 None
 1.08A 6a4iA-4mggA:
undetectable		 6a4iA-4mggA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 5 ILE A 266
SER A 267
ALA A 108
LEU A 121
 None
 1.01A 6dwnA-4mggA:
undetectable		 6dwnA-4mggA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 10 GLY A 296
GLU A  49
VAL A  35
CYH A  51
ILE A 352
 None
 1.18A 6exiA-4mggA:
undetectable		 6exiA-4mggA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 10 GLY A 296
GLU A  49
VAL A  35
CYH A  51
ILE A 352
 None
 1.18A 6exiB-4mggA:
undetectable		 6exiB-4mggA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 GLY A 296
GLU A  49
VAL A  35
CYH A  51
ILE A 352
 None
 1.18A 6exiC-4mggA:
undetectable
6exiD-4mggA:
2.2		 6exiC-4mggA:
11.86
6exiD-4mggA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		5 / 12 GLY A 296
GLU A  49
VAL A  35
CYH A  51
ILE A 352
 None
 1.21A 6exiC-4mggA:
undetectable
6exiD-4mggA:
2.2		 6exiC-4mggA:
11.86
6exiD-4mggA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		3 / 3 LEU A 264
LEU A 307
ARG A 279
 None
 0.51A 6fgcA-4mggA:
undetectable		 6fgcA-4mggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		3 / 3 LEU A 264
LEU A 307
ARG A 279
 None
 0.55A 6fgdA-4mggA:
undetectable		 6fgdA-4mggA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 5 LEU A 222
THR A 196
THR A 199
GLY A 197
 None
None
None
MG  A 403 (-4.0A)
 1.27A 6gtqA-4mggA:
undetectable		 6gtqA-4mggA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4mgg MUCONATE LACTONIZING
ENZYME
(Labrenzia
aggregata) 		4 / 6 GLY A 197
THR A 196
ARG A 200
SER A 227
 MG  A 403 (-4.0A)
None
None
None
 0.98A 6jogA-4mggA:
undetectable		 6jogA-4mggA:
20.29