SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mgq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 4mgq GLYCOSYL HYDROLASE
FAMILY 10
(Prevotella
bryantii) 		4 / 8 SER A 214
PHE A 228
ALA A 230
LEU A 178
 None
 1.13A 2bxkA-4mgqA:
undetectable		 2bxkA-4mgqA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4mgq GLYCOSYL HYDROLASE
FAMILY 10
(Prevotella
bryantii) 		4 / 7 THR A 212
PRO A 213
GLU A 240
PRO A 202
 None
 1.05A 2v2gC-4mgqA:
undetectable
2v2gD-4mgqA:
undetectable		 2v2gC-4mgqA:
22.51
2v2gD-4mgqA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 4mgq GLYCOSYL HYDROLASE
FAMILY 10
(Prevotella
bryantii) 		4 / 6 ARG A 238
ASN A 165
TRP A 166
GLU A 240
 None
 1.42A 3galB-4mgqA:
undetectable		 3galB-4mgqA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4mgq GLYCOSYL HYDROLASE
FAMILY 10
(Prevotella
bryantii) 		5 / 12 LEU A 255
TRP A 276
LEU A 154
LEU A 186
LEU A 241
 None
 1.00A 5ienB-4mgqA:
undetectable		 5ienB-4mgqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 4mgq GLYCOSYL HYDROLASE
FAMILY 10
(Prevotella
bryantii) 		5 / 12 VAL A 172
LEU A 188
TRP A 276
LEU A 154
ILE A 156
 None
 1.27A 5xprA-4mgqA:
undetectable		 5xprA-4mgqA:
15.14