SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		3 / 3 GLU A 324
ILE A 323
ARG A  82
 None
 0.63A 1cd2A-4mguA:
undetectable		 1cd2A-4mguA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 8 SER A  99
ILE A 323
LEU A 255
ASP A  81
 None
 0.80A 1jg4A-4mguA:
undetectable		 1jg4A-4mguA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 5 TYR A 288
PRO A 335
THR A 400
SER A 326
 None
 1.42A 1ymxA-4mguA:
undetectable		 1ymxA-4mguA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 8 LEU A 412
VAL A 148
GLY A 147
ASP A  68
 None
 0.79A 2a1oA-4mguA:
undetectable		 2a1oA-4mguA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		3 / 3 SER A 304
TYR A 288
ASP A 403
 None
 0.90A 4rp8C-4mguA:
undetectable		 4rp8C-4mguA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 8 TYR A 181
ILE A  72
SER A  74
GLY A  76
 None
 0.82A 5alcL-4mguA:
undetectable		 5alcL-4mguA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 6 TYR A 249
TYR A  86
GLY A 254
GLU A 324
 None
 1.16A 5emlA-4mguA:
undetectable		 5emlA-4mguA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 5 TYR A 209
LEU A 136
PRO A 343
LEU A 364
 None
 1.48A 5eshA-4mguA:
undetectable		 5eshA-4mguA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		4 / 6 ASN A 368
THR A  47
ASN A 366
ILE A 135
 None
 1.11A 5uigA-4mguA:
undetectable		 5uigA-4mguA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		5 / 9 LEU A 253
GLY A 397
LEU A 329
THR A 400
VAL A 311
 None
 1.22A 6czmA-4mguA:
undetectable
6czmB-4mguA:
undetectable		 6czmA-4mguA:
21.21
6czmB-4mguA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		5 / 9 LEU A 253
GLY A 397
LEU A 329
THR A 400
VAL A 311
 None
 1.23A 6czmB-4mguA:
undetectable
6czmC-4mguA:
undetectable		 6czmB-4mguA:
21.21
6czmC-4mguA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		5 / 9 LEU A 253
GLY A 397
LEU A 329
THR A 400
VAL A 311
 None
 1.24A 6czmD-4mguA:
undetectable
6czmE-4mguA:
undetectable		 6czmD-4mguA:
21.21
6czmE-4mguA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4mgu STRUCTURAL PROTEIN
VP2
(Orthopteran
ambidensovirus
1) 		5 / 10 LEU A 253
GLY A 397
LEU A 329
THR A 400
VAL A 311
 None
 1.24A 6czmE-4mguA:
undetectable
6czmF-4mguA:
undetectable		 6czmE-4mguA:
21.21
6czmF-4mguA:
21.21