SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 1d1wA-4mh1A:
undetectable
1d1wB-4mh1A:
undetectable
1d1wA-4mh1A:
22.50
1d1wB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ALA A 552
VAL A  40
TRP A 494
None
0.92A 1jnoA-4mh1A:
undetectable
1jnoA-4mh1A:
3.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ALA A 552
VAL A  40
TRP A 494
None
0.92A 1jnoB-4mh1A:
undetectable
1jnoB-4mh1A:
3.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 1k2uA-4mh1A:
undetectable
1k2uB-4mh1A:
undetectable
1k2uA-4mh1A:
21.28
1k2uB-4mh1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 1lzzA-4mh1A:
undetectable
1lzzB-4mh1A:
undetectable
1lzzA-4mh1A:
21.28
1lzzB-4mh1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 10 ASP A 442
GLY A 383
GLU A 456
GLY A 439
ARG A 457
None
1.21A 1mehA-4mh1A:
undetectable
1mehA-4mh1A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 1mmvA-4mh1A:
undetectable
1mmvB-4mh1A:
undetectable
1mmvA-4mh1A:
21.28
1mmvB-4mh1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 GLY A 219
VAL A 177
TYR A 223
ASN A 228
ARG A 258
None
1.16A 1n2xA-4mh1A:
undetectable
1n2xA-4mh1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ALA A 552
VAL A  40
TRP A 494
None
0.95A 1nruA-4mh1A:
undetectable
1nruA-4mh1A:
3.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ALA A 552
VAL A  40
TRP A 494
None
0.94A 1nruB-4mh1A:
undetectable
1nruB-4mh1A:
3.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.44A 1om4A-4mh1A:
undetectable
1om4B-4mh1A:
undetectable
1om4A-4mh1A:
21.16
1om4B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 GLY A 165
PHE A 176
ASN A 191
ARG A 142
None
0.94A 1oniG-4mh1A:
undetectable
1oniI-4mh1A:
undetectable
1oniG-4mh1A:
14.34
1oniI-4mh1A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 1p6jA-4mh1A:
undetectable
1p6jB-4mh1A:
undetectable
1p6jA-4mh1A:
21.20
1p6jB-4mh1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 1p6lA-4mh1A:
undetectable
1p6lB-4mh1A:
undetectable
1p6lA-4mh1A:
22.05
1p6lB-4mh1A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 1p6lA-4mh1A:
undetectable
1p6lB-4mh1A:
undetectable
1p6lA-4mh1A:
22.05
1p6lB-4mh1A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 GLU A  38
LEU A  43
GLU A 491
ALA A 484
VAL A 472
None
1.03A 1sn5B-4mh1A:
undetectable
1sn5D-4mh1A:
undetectable
1sn5B-4mh1A:
12.47
1sn5D-4mh1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 GLU A 491
ALA A 484
VAL A 472
GLU A  38
LEU A  43
None
1.03A 1sn5B-4mh1A:
undetectable
1sn5D-4mh1A:
undetectable
1sn5B-4mh1A:
12.47
1sn5D-4mh1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 1zzqA-4mh1A:
undetectable
1zzqB-4mh1A:
undetectable
1zzqA-4mh1A:
21.48
1zzqB-4mh1A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 ARG A 385
LEU A 403
ALA A 443
ILE A 444
ALA A 390
None
1.15A 2bxpA-4mh1A:
undetectable
2bxpA-4mh1A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 9 GLN A 487
GLU A  38
ASN A  39
ILE A  35
VAL A 517
None
1.28A 2drdA-4mh1A:
undetectable
2drdA-4mh1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A  49
GLN A  77
ASN A  71
LEU A 112
None
1.21A 2nyrA-4mh1A:
undetectable
2nyrA-4mh1A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 ALA A 111
LEU A 126
PHE A 119
SER A 121
ARG A  92
None
1.14A 2oipA-4mh1A:
undetectable
2oipA-4mh1A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 ALA A 111
LEU A 126
PHE A 119
SER A 121
ARG A  92
None
1.16A 2oipD-4mh1A:
undetectable
2oipD-4mh1A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 ASP A 123
HIS A 125
ASP A 139
PHE A 119
LEU A  94
None
1.31A 2q0jB-4mh1A:
undetectable
2q0jB-4mh1A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 GLU A 456
ILE A 438
GLY A 439
LYS A 435
None
1.16A 2qeuA-4mh1A:
undetectable
2qeuC-4mh1A:
undetectable
2qeuA-4mh1A:
14.56
2qeuC-4mh1A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 3b3mA-4mh1A:
undetectable
3b3mB-4mh1A:
undetectable
3b3mA-4mh1A:
21.16
3b3mB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 3b3oA-4mh1A:
undetectable
3b3oB-4mh1A:
undetectable
3b3oA-4mh1A:
21.16
3b3oB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ARG A 385
VAL A 290
THR A 222
None
0.82A 3cyxA-4mh1A:
undetectable
3cyxA-4mh1A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 PRO A 402
LEU A 473
ALA A 391
PRO A 464
None
1.33A 3gv1A-4mh1A:
undetectable
3gv1C-4mh1A:
undetectable
3gv1A-4mh1A:
12.99
3gv1C-4mh1A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 LEU A 473
ALA A 391
PRO A 464
PRO A 402
None
1.35A 3gv1A-4mh1A:
undetectable
3gv1B-4mh1A:
undetectable
3gv1A-4mh1A:
12.99
3gv1B-4mh1A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 ALA A 111
LEU A 126
PHE A 119
SER A 121
ARG A  92
None
1.14A 3hj3A-4mh1A:
undetectable
3hj3A-4mh1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3jt3A-4mh1A:
undetectable
3jt3B-4mh1A:
undetectable
3jt3A-4mh1A:
21.16
3jt3B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 3jt4A-4mh1A:
undetectable
3jt4B-4mh1A:
undetectable
3jt4A-4mh1A:
21.16
3jt4B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.45A 3jt4A-4mh1A:
undetectable
3jt4B-4mh1A:
undetectable
3jt4A-4mh1A:
21.16
3jt4B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 3jt8A-4mh1A:
undetectable
3jt8B-4mh1A:
undetectable
3jt8A-4mh1A:
21.16
3jt8B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.36A 3jwtA-4mh1A:
undetectable
3jwtB-4mh1A:
undetectable
3jwtA-4mh1A:
21.34
3jwtB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3jwtA-4mh1A:
undetectable
3jwtB-4mh1A:
undetectable
3jwtA-4mh1A:
21.34
3jwtB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3jwuA-4mh1A:
undetectable
3jwuB-4mh1A:
undetectable
3jwuA-4mh1A:
21.34
3jwuB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 3jwvA-4mh1A:
undetectable
3jwvB-4mh1A:
undetectable
3jwvA-4mh1A:
21.34
3jwvB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3jwvA-4mh1A:
undetectable
3jwvB-4mh1A:
undetectable
3jwvA-4mh1A:
21.34
3jwvB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.33A 3jwxA-4mh1A:
undetectable
3jwxB-4mh1A:
undetectable
3jwxA-4mh1A:
22.50
3jwxB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3jwxA-4mh1A:
undetectable
3jwxB-4mh1A:
undetectable
3jwxA-4mh1A:
22.50
3jwxB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3jx1A-4mh1A:
undetectable
3jx1B-4mh1A:
undetectable
3jx1A-4mh1A:
21.40
3jx1B-4mh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 8 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3jx1A-4mh1A:
undetectable
3jx1B-4mh1A:
undetectable
3jx1A-4mh1A:
21.40
3jx1B-4mh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 GLY A 383
ASN A 531
VAL A 539
GLY A 439
ILE A 438
None
0.81A 3k13B-4mh1A:
undetectable
3k13B-4mh1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 ASN A 531
ASP A 479
ARG A 108
None
0.91A 3k13C-4mh1A:
undetectable
3k13C-4mh1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 3n2rA-4mh1A:
undetectable
3n2rB-4mh1A:
undetectable
3n2rA-4mh1A:
21.16
3n2rB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 3n2rA-4mh1A:
undetectable
3n2rB-4mh1A:
undetectable
3n2rA-4mh1A:
21.16
3n2rB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3n5tA-4mh1A:
undetectable
3n5tB-4mh1A:
undetectable
3n5tA-4mh1A:
22.50
3n5tB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3n5vA-4mh1A:
undetectable
3n5vB-4mh1A:
undetectable
3n5vA-4mh1A:
21.16
3n5vB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3n5vA-4mh1A:
undetectable
3n5vB-4mh1A:
undetectable
3n5vA-4mh1A:
21.16
3n5vB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3n5yA-4mh1A:
undetectable
3n5yB-4mh1A:
undetectable
3n5yA-4mh1A:
21.16
3n5yB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3n5yA-4mh1A:
undetectable
3n5yB-4mh1A:
undetectable
3n5yA-4mh1A:
21.16
3n5yB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 3n5zA-4mh1A:
undetectable
3n5zB-4mh1A:
undetectable
3n5zA-4mh1A:
21.16
3n5zB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3n5zA-4mh1A:
undetectable
3n5zB-4mh1A:
undetectable
3n5zA-4mh1A:
21.16
3n5zB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 3n67A-4mh1A:
undetectable
3n67B-4mh1A:
undetectable
3n67A-4mh1A:
22.11
3n67B-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.34A 3n69A-4mh1A:
0.0
3n69B-4mh1A:
0.0
3n69A-4mh1A:
22.11
3n69B-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3n69A-4mh1A:
0.0
3n69B-4mh1A:
0.0
3n69A-4mh1A:
22.11
3n69B-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3n6eA-4mh1A:
undetectable
3n6eB-4mh1A:
undetectable
3n6eA-4mh1A:
22.11
3n6eB-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3n6eA-4mh1A:
undetectable
3n6eB-4mh1A:
undetectable
3n6eA-4mh1A:
22.11
3n6eB-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3n6gA-4mh1A:
undetectable
3n6gB-4mh1A:
undetectable
3n6gA-4mh1A:
22.11
3n6gB-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3nleA-4mh1A:
undetectable
3nleB-4mh1A:
undetectable
3nleA-4mh1A:
22.50
3nleB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.36A 3nliA-4mh1A:
undetectable
3nliB-4mh1A:
undetectable
3nliA-4mh1A:
22.11
3nliB-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3nliA-4mh1A:
undetectable
3nliB-4mh1A:
undetectable
3nliA-4mh1A:
22.11
3nliB-4mh1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3nlkA-4mh1A:
undetectable
3nlkB-4mh1A:
undetectable
3nlkA-4mh1A:
21.34
3nlkB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3nlkA-4mh1A:
undetectable
3nlkB-4mh1A:
undetectable
3nlkA-4mh1A:
21.34
3nlkB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3nlmA-4mh1A:
undetectable
3nlmB-4mh1A:
undetectable
3nlmA-4mh1A:
21.16
3nlmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3nlmA-4mh1A:
undetectable
3nlmB-4mh1A:
undetectable
3nlmA-4mh1A:
21.16
3nlmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3nlnA-4mh1A:
undetectable
3nlnB-4mh1A:
undetectable
3nlnA-4mh1A:
21.34
3nlnB-4mh1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.36A 3nluA-4mh1A:
undetectable
3nluB-4mh1A:
undetectable
3nluA-4mh1A:
22.50
3nluB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.33A 3nluA-4mh1A:
0.0
3nluB-4mh1A:
0.0
3nluA-4mh1A:
22.50
3nluB-4mh1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3nlvA-4mh1A:
undetectable
3nlvB-4mh1A:
undetectable
3nlvA-4mh1A:
21.16
3nlvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3nlvA-4mh1A:
undetectable
3nlvB-4mh1A:
undetectable
3nlvA-4mh1A:
21.16
3nlvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 3nlwA-4mh1A:
undetectable
3nlwB-4mh1A:
undetectable
3nlwA-4mh1A:
21.16
3nlwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 3nlwA-4mh1A:
undetectable
3nlwB-4mh1A:
undetectable
3nlwA-4mh1A:
21.16
3nlwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3nlxA-4mh1A:
undetectable
3nlxB-4mh1A:
undetectable
3nlxA-4mh1A:
21.16
3nlxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3nlxA-4mh1A:
undetectable
3nlxB-4mh1A:
undetectable
3nlxA-4mh1A:
21.16
3nlxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.35A 3nlyA-4mh1A:
undetectable
3nlyB-4mh1A:
undetectable
3nlyA-4mh1A:
21.16
3nlyB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 8 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3nlyA-4mh1A:
undetectable
3nlyB-4mh1A:
undetectable
3nlyA-4mh1A:
21.16
3nlyB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3nlzA-4mh1A:
undetectable
3nlzB-4mh1A:
undetectable
3nlzA-4mh1A:
21.16
3nlzB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3nlzA-4mh1A:
undetectable
3nlzB-4mh1A:
undetectable
3nlzA-4mh1A:
21.16
3nlzB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3nm0A-4mh1A:
undetectable
3nm0B-4mh1A:
undetectable
3nm0A-4mh1A:
21.16
3nm0B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3nm0A-4mh1A:
undetectable
3nm0B-4mh1A:
undetectable
3nm0A-4mh1A:
21.16
3nm0B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3nnyA-4mh1A:
undetectable
3nnyB-4mh1A:
undetectable
3nnyA-4mh1A:
21.16
3nnyB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3nnyA-4mh1A:
undetectable
3nnyB-4mh1A:
undetectable
3nnyA-4mh1A:
21.16
3nnyB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 3nnzA-4mh1A:
undetectable
3nnzB-4mh1A:
undetectable
3nnzA-4mh1A:
21.16
3nnzB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3nnzA-4mh1A:
undetectable
3nnzB-4mh1A:
undetectable
3nnzA-4mh1A:
21.16
3nnzB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ILE A 354
HIS A 272
PRO A 276
ASP A 355
None
1.25A 3oi8A-4mh1A:
undetectable
3oi8A-4mh1A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3pneA-4mh1A:
undetectable
3pneB-4mh1A:
undetectable
3pneA-4mh1A:
21.16
3pneB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3pneA-4mh1A:
undetectable
3pneB-4mh1A:
undetectable
3pneA-4mh1A:
21.16
3pneB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 3pnfA-4mh1A:
undetectable
3pnfB-4mh1A:
undetectable
3pnfA-4mh1A:
21.16
3pnfB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 3pnfA-4mh1A:
undetectable
3pnfB-4mh1A:
undetectable
3pnfA-4mh1A:
21.16
3pnfB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 3pngA-4mh1A:
undetectable
3pngB-4mh1A:
undetectable
3pngA-4mh1A:
21.16
3pngB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3pngA-4mh1A:
undetectable
3pngB-4mh1A:
undetectable
3pngA-4mh1A:
21.16
3pngB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3pnhA-4mh1A:
undetectable
3pnhB-4mh1A:
undetectable
3pnhA-4mh1A:
22.22
3pnhB-4mh1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3pnhA-4mh1A:
undetectable
3pnhB-4mh1A:
undetectable
3pnhA-4mh1A:
22.22
3pnhB-4mh1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3q99A-4mh1A:
undetectable
3q99B-4mh1A:
undetectable
3q99A-4mh1A:
21.16
3q99B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3rqjA-4mh1A:
undetectable
3rqjB-4mh1A:
undetectable
3rqjA-4mh1A:
21.16
3rqjB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3rqjA-4mh1A:
undetectable
3rqjB-4mh1A:
undetectable
3rqjA-4mh1A:
21.16
3rqjB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3rqkA-4mh1A:
undetectable
3rqkB-4mh1A:
undetectable
3rqkA-4mh1A:
21.16
3rqkB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3rqkA-4mh1A:
undetectable
3rqkB-4mh1A:
undetectable
3rqkA-4mh1A:
21.16
3rqkB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.35A 3rqlA-4mh1A:
undetectable
3rqlB-4mh1A:
undetectable
3rqlA-4mh1A:
21.16
3rqlB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 8 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3rqlA-4mh1A:
undetectable
3rqlB-4mh1A:
undetectable
3rqlA-4mh1A:
21.16
3rqlB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3rqmA-4mh1A:
undetectable
3rqmB-4mh1A:
undetectable
3rqmA-4mh1A:
21.16
3rqmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3rqmA-4mh1A:
undetectable
3rqmB-4mh1A:
undetectable
3rqmA-4mh1A:
21.16
3rqmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3rqnA-4mh1A:
undetectable
3rqnB-4mh1A:
undetectable
3rqnA-4mh1A:
21.16
3rqnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3rqnA-4mh1A:
undetectable
3rqnB-4mh1A:
undetectable
3rqnA-4mh1A:
21.16
3rqnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.34A 3rqoA-4mh1A:
undetectable
3rqoB-4mh1A:
undetectable
3rqoA-4mh1A:
22.37
3rqoB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 3rqoA-4mh1A:
undetectable
3rqoB-4mh1A:
undetectable
3rqoA-4mh1A:
22.37
3rqoB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.33A 3rqpA-4mh1A:
undetectable
3rqpB-4mh1A:
undetectable
3rqpA-4mh1A:
22.37
3rqpB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3rqpA-4mh1A:
0.0
3rqpB-4mh1A:
0.0
3rqpA-4mh1A:
22.37
3rqpB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 4 LEU A 530
GLY A 529
GLY A 527
THR A 478
None
0.93A 3si7A-4mh1A:
undetectable
3si7A-4mh1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3svpA-4mh1A:
undetectable
3svpB-4mh1A:
undetectable
3svpA-4mh1A:
21.16
3svpB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3svqA-4mh1A:
undetectable
3svqB-4mh1A:
undetectable
3svqA-4mh1A:
21.16
3svqB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 THR A 448
GLY A 314
ARG A 343
MET A 329
GLU A 302
None
1.35A 3tkaA-4mh1A:
undetectable
3tkaA-4mh1A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 3tylA-4mh1A:
undetectable
3tylB-4mh1A:
undetectable
3tylA-4mh1A:
21.16
3tylB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3tylA-4mh1A:
undetectable
3tylB-4mh1A:
undetectable
3tylA-4mh1A:
21.16
3tylB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 3tymA-4mh1A:
undetectable
3tymB-4mh1A:
undetectable
3tymA-4mh1A:
21.16
3tymB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3tymA-4mh1A:
undetectable
3tymB-4mh1A:
undetectable
3tymA-4mh1A:
21.16
3tymB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 3tynA-4mh1A:
undetectable
3tynB-4mh1A:
undetectable
3tynA-4mh1A:
21.16
3tynB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 3tynA-4mh1A:
undetectable
3tynB-4mh1A:
undetectable
3tynA-4mh1A:
21.16
3tynB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 3tyoA-4mh1A:
undetectable
3tyoB-4mh1A:
undetectable
3tyoA-4mh1A:
21.16
3tyoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 3tyoA-4mh1A:
undetectable
3tyoB-4mh1A:
undetectable
3tyoA-4mh1A:
21.16
3tyoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3ufoA-4mh1A:
undetectable
3ufoB-4mh1A:
undetectable
3ufoA-4mh1A:
21.16
3ufoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 3ufrA-4mh1A:
undetectable
3ufrB-4mh1A:
undetectable
3ufrA-4mh1A:
21.16
3ufrB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 3ufsA-4mh1A:
undetectable
3ufsB-4mh1A:
undetectable
3ufsA-4mh1A:
21.16
3ufsB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 3ufsA-4mh1A:
undetectable
3ufsB-4mh1A:
undetectable
3ufsA-4mh1A:
21.16
3ufsB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3ufuA-4mh1A:
undetectable
3ufuB-4mh1A:
undetectable
3ufuA-4mh1A:
21.16
3ufuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3ufuA-4mh1A:
undetectable
3ufuB-4mh1A:
undetectable
3ufuA-4mh1A:
21.16
3ufuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 3ufvA-4mh1A:
undetectable
3ufvB-4mh1A:
undetectable
3ufvA-4mh1A:
21.16
3ufvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 3ufvA-4mh1A:
undetectable
3ufvB-4mh1A:
undetectable
3ufvA-4mh1A:
21.16
3ufvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 3ufwA-4mh1A:
undetectable
3ufwB-4mh1A:
undetectable
3ufwA-4mh1A:
21.16
3ufwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 3ufwA-4mh1A:
undetectable
3ufwB-4mh1A:
undetectable
3ufwA-4mh1A:
21.16
3ufwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 4c39A-4mh1A:
undetectable
4c39B-4mh1A:
undetectable
4c39A-4mh1A:
21.16
4c39B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 TYR A  68
MET A  67
ILE A 519
None
0.92A 4c8bB-4mh1A:
undetectable
4c8bB-4mh1A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4camA-4mh1A:
undetectable
4camB-4mh1A:
undetectable
4camA-4mh1A:
21.16
4camB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 4caoA-4mh1A:
undetectable
4caoB-4mh1A:
undetectable
4caoA-4mh1A:
21.16
4caoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 4caoA-4mh1A:
undetectable
4caoB-4mh1A:
undetectable
4caoA-4mh1A:
21.16
4caoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4capA-4mh1A:
undetectable
4capB-4mh1A:
undetectable
4capA-4mh1A:
21.16
4capB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 8 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4capA-4mh1A:
undetectable
4capB-4mh1A:
undetectable
4capA-4mh1A:
21.16
4capB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4ctpA-4mh1A:
undetectable
4ctpB-4mh1A:
undetectable
4ctpA-4mh1A:
21.16
4ctpB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4ctpA-4mh1A:
undetectable
4ctpB-4mh1A:
undetectable
4ctpA-4mh1A:
21.16
4ctpB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4ctqA-4mh1A:
undetectable
4ctqB-4mh1A:
undetectable
4ctqA-4mh1A:
21.16
4ctqB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.42A 4ctqA-4mh1A:
undetectable
4ctqB-4mh1A:
undetectable
4ctqA-4mh1A:
21.16
4ctqB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4ctrA-4mh1A:
undetectable
4ctrB-4mh1A:
undetectable
4ctrA-4mh1A:
21.16
4ctrB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4cttA-4mh1A:
undetectable
4cttB-4mh1A:
undetectable
4cttA-4mh1A:
21.16
4cttB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 4ctuA-4mh1A:
undetectable
4ctuB-4mh1A:
undetectable
4ctuA-4mh1A:
21.16
4ctuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4ctuA-4mh1A:
undetectable
4ctuB-4mh1A:
undetectable
4ctuA-4mh1A:
21.16
4ctuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 4ctvA-4mh1A:
undetectable
4ctvB-4mh1A:
undetectable
4ctvA-4mh1A:
21.16
4ctvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4ctvA-4mh1A:
undetectable
4ctvB-4mh1A:
undetectable
4ctvA-4mh1A:
21.16
4ctvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 4ctwA-4mh1A:
undetectable
4ctwB-4mh1A:
undetectable
4ctwA-4mh1A:
21.16
4ctwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4ctwA-4mh1A:
undetectable
4ctwB-4mh1A:
undetectable
4ctwA-4mh1A:
21.16
4ctwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 4ctxA-4mh1A:
undetectable
4ctxB-4mh1A:
undetectable
4ctxA-4mh1A:
21.16
4ctxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4ctxA-4mh1A:
undetectable
4ctxB-4mh1A:
undetectable
4ctxA-4mh1A:
21.16
4ctxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.33A 4ctyA-4mh1A:
undetectable
4ctyB-4mh1A:
undetectable
4ctyA-4mh1A:
22.37
4ctyB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.33A 4ctyA-4mh1A:
undetectable
4ctyB-4mh1A:
undetectable
4ctyA-4mh1A:
22.37
4ctyB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 4cx5A-4mh1A:
undetectable
4cx5B-4mh1A:
undetectable
4cx5A-4mh1A:
21.16
4cx5B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4cx5A-4mh1A:
undetectable
4cx5B-4mh1A:
undetectable
4cx5A-4mh1A:
21.16
4cx5B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 4cx6A-4mh1A:
undetectable
4cx6B-4mh1A:
undetectable
4cx6A-4mh1A:
21.16
4cx6B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.45A 4d1nC-4mh1A:
undetectable
4d1nD-4mh1A:
undetectable
4d1nC-4mh1A:
21.13
4d1nD-4mh1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 4d2yA-4mh1A:
undetectable
4d2yB-4mh1A:
undetectable
4d2yA-4mh1A:
21.16
4d2yB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 4d30A-4mh1A:
undetectable
4d30B-4mh1A:
undetectable
4d30A-4mh1A:
21.16
4d30B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4d30A-4mh1A:
undetectable
4d30B-4mh1A:
undetectable
4d30A-4mh1A:
21.16
4d30B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 4d31A-4mh1A:
undetectable
4d31B-4mh1A:
undetectable
4d31A-4mh1A:
21.16
4d31B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 4d31A-4mh1A:
undetectable
4d31B-4mh1A:
undetectable
4d31A-4mh1A:
21.16
4d31B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4d37A-4mh1A:
undetectable
4d37B-4mh1A:
undetectable
4d37A-4mh1A:
22.37
4d37B-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 4d7oA-4mh1A:
undetectable
4d7oB-4mh1A:
undetectable
4d7oA-4mh1A:
21.16
4d7oB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4d7oA-4mh1A:
undetectable
4d7oB-4mh1A:
undetectable
4d7oA-4mh1A:
21.16
4d7oB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 GLY A 266
VAL A 261
PRO A 263
TYR A 223
None
0.87A 4dxuA-4mh1A:
undetectable
4dxuA-4mh1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4euxA-4mh1A:
undetectable
4euxB-4mh1A:
undetectable
4euxA-4mh1A:
21.16
4euxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 4euxA-4mh1A:
undetectable
4euxB-4mh1A:
undetectable
4euxA-4mh1A:
21.16
4euxB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 4fw0A-4mh1A:
undetectable
4fw0B-4mh1A:
undetectable
4fw0A-4mh1A:
21.16
4fw0B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.36A 4imtA-4mh1A:
undetectable
4imtB-4mh1A:
undetectable
4imtA-4mh1A:
21.16
4imtB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.38A 4imwA-4mh1A:
undetectable
4imwB-4mh1A:
undetectable
4imwA-4mh1A:
21.16
4imwB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4jsfA-4mh1A:
undetectable
4jsfB-4mh1A:
undetectable
4jsfA-4mh1A:
21.16
4jsfB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4jsfA-4mh1A:
undetectable
4jsfB-4mh1A:
undetectable
4jsfA-4mh1A:
21.16
4jsfB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4jsgA-4mh1A:
undetectable
4jsgB-4mh1A:
undetectable
4jsgA-4mh1A:
21.16
4jsgB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 4jsgA-4mh1A:
undetectable
4jsgB-4mh1A:
undetectable
4jsgA-4mh1A:
21.16
4jsgB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.36A 4jsiA-4mh1A:
undetectable
4jsiB-4mh1A:
undetectable
4jsiA-4mh1A:
21.16
4jsiB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 4kchA-4mh1A:
undetectable
4kchB-4mh1A:
undetectable
4kchA-4mh1A:
21.16
4kchB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 4kciA-4mh1A:
undetectable
4kciB-4mh1A:
undetectable
4kciA-4mh1A:
21.16
4kciB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4kckA-4mh1A:
undetectable
4kckB-4mh1A:
undetectable
4kckA-4mh1A:
21.16
4kckB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 4kckA-4mh1A:
undetectable
4kckB-4mh1A:
undetectable
4kckA-4mh1A:
21.16
4kckB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 4kclA-4mh1A:
undetectable
4kclB-4mh1A:
undetectable
4kclA-4mh1A:
21.16
4kclB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4kclA-4mh1A:
undetectable
4kclB-4mh1A:
undetectable
4kclA-4mh1A:
21.16
4kclB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4kcmA-4mh1A:
undetectable
4kcmB-4mh1A:
undetectable
4kcmA-4mh1A:
21.16
4kcmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4kcmA-4mh1A:
undetectable
4kcmB-4mh1A:
undetectable
4kcmA-4mh1A:
21.16
4kcmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4kcnA-4mh1A:
undetectable
4kcnB-4mh1A:
undetectable
4kcnA-4mh1A:
21.16
4kcnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.42A 4kcnA-4mh1A:
undetectable
4kcnB-4mh1A:
undetectable
4kcnA-4mh1A:
21.16
4kcnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 4kcoA-4mh1A:
undetectable
4kcoB-4mh1A:
undetectable
4kcoA-4mh1A:
21.16
4kcoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 4kcoA-4mh1A:
undetectable
4kcoB-4mh1A:
undetectable
4kcoA-4mh1A:
21.16
4kcoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.13A 4qvvH-4mh1A:
undetectable
4qvvH-4mh1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.13A 4qvvV-4mh1A:
undetectable
4qvvV-4mh1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.11A 4qvyH-4mh1A:
undetectable
4qvyH-4mh1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.11A 4qvyV-4mh1A:
undetectable
4qvyW-4mh1A:
undetectable
4qvyV-4mh1A:
19.34
4qvyW-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.14A 4qw0H-4mh1A:
undetectable
4qw0I-4mh1A:
undetectable
4qw0H-4mh1A:
19.34
4qw0I-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.14A 4qw0V-4mh1A:
undetectable
4qw0W-4mh1A:
undetectable
4qw0V-4mh1A:
19.34
4qw0W-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.17A 4qw1H-4mh1A:
undetectable
4qw1I-4mh1A:
undetectable
4qw1H-4mh1A:
19.34
4qw1I-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 4uh5A-4mh1A:
undetectable
4uh5B-4mh1A:
undetectable
4uh5A-4mh1A:
21.09
4uh5B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 4upmA-4mh1A:
undetectable
4upmB-4mh1A:
undetectable
4upmA-4mh1A:
21.16
4upmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4upmA-4mh1A:
undetectable
4upmB-4mh1A:
undetectable
4upmA-4mh1A:
21.16
4upmB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4upnA-4mh1A:
undetectable
4upnB-4mh1A:
undetectable
4upnA-4mh1A:
21.16
4upnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.36A 4upnA-4mh1A:
undetectable
4upnB-4mh1A:
undetectable
4upnA-4mh1A:
21.16
4upnB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.42A 4upoA-4mh1A:
undetectable
4upoB-4mh1A:
undetectable
4upoA-4mh1A:
21.16
4upoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4uprA-4mh1A:
undetectable
4uprB-4mh1A:
undetectable
4uprA-4mh1A:
22.37
4uprB-4mh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 4v3uA-4mh1A:
undetectable
4v3uB-4mh1A:
undetectable
4v3uA-4mh1A:
21.13
4v3uB-4mh1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4v3uC-4mh1A:
undetectable
4v3uD-4mh1A:
undetectable
4v3uC-4mh1A:
21.13
4v3uD-4mh1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.37A 4v3vA-4mh1A:
undetectable
4v3vB-4mh1A:
undetectable
4v3vA-4mh1A:
21.16
4v3vB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 4v3vA-4mh1A:
undetectable
4v3vB-4mh1A:
undetectable
4v3vA-4mh1A:
21.16
4v3vB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 4v3xA-4mh1A:
undetectable
4v3xB-4mh1A:
undetectable
4v3xA-4mh1A:
21.16
4v3xB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 4v3yA-4mh1A:
undetectable
4v3yB-4mh1A:
undetectable
4v3yA-4mh1A:
21.16
4v3yB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 4v3zA-4mh1A:
undetectable
4v3zB-4mh1A:
undetectable
4v3zA-4mh1A:
21.16
4v3zB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.35A 5ad4A-4mh1A:
undetectable
5ad4B-4mh1A:
undetectable
5ad4A-4mh1A:
21.16
5ad4B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.37A 5ad4A-4mh1A:
undetectable
5ad4B-4mh1A:
undetectable
5ad4A-4mh1A:
21.16
5ad4B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 5ad6A-4mh1A:
undetectable
5ad6B-4mh1A:
undetectable
5ad6A-4mh1A:
21.16
5ad6B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 5agoA-4mh1A:
undetectable
5agoB-4mh1A:
undetectable
5agoA-4mh1A:
21.16
5agoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.14A 5bxnH-4mh1A:
undetectable
5bxnI-4mh1A:
undetectable
5bxnH-4mh1A:
19.34
5bxnI-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.15A 5cz7V-4mh1A:
undetectable
5cz7W-4mh1A:
undetectable
5cz7V-4mh1A:
19.34
5cz7W-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 11 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.14A 5d0xV-4mh1A:
undetectable
5d0xV-4mh1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 5fvrA-4mh1A:
undetectable
5fvrB-4mh1A:
undetectable
5fvrA-4mh1A:
21.16
5fvrB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.46A 5fvrA-4mh1A:
undetectable
5fvrB-4mh1A:
undetectable
5fvrA-4mh1A:
21.16
5fvrB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.46A 5fvtA-4mh1A:
undetectable
5fvtB-4mh1A:
undetectable
5fvtA-4mh1A:
21.16
5fvtB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.45A 5fvtA-4mh1A:
undetectable
5fvtB-4mh1A:
undetectable
5fvtA-4mh1A:
21.16
5fvtB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 5fvvA-4mh1A:
undetectable
5fvvB-4mh1A:
undetectable
5fvvA-4mh1A:
21.09
5fvvB-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.45A 5fvvA-4mh1A:
undetectable
5fvvB-4mh1A:
undetectable
5fvvA-4mh1A:
21.09
5fvvB-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 5fvwA-4mh1A:
undetectable
5fvwB-4mh1A:
undetectable
5fvwA-4mh1A:
21.09
5fvwB-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 5fw0A-4mh1A:
undetectable
5fw0B-4mh1A:
undetectable
5fw0A-4mh1A:
21.16
5fw0B-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 5g0nA-4mh1A:
undetectable
5g0nB-4mh1A:
undetectable
5g0nA-4mh1A:
21.40
5g0nB-4mh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 5g0oA-4mh1A:
undetectable
5g0oB-4mh1A:
undetectable
5g0oA-4mh1A:
21.40
5g0oB-4mh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 5g0oA-4mh1A:
undetectable
5g0oB-4mh1A:
undetectable
5g0oA-4mh1A:
21.40
5g0oB-4mh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ILE A  35
TYR A 516
VAL A 517
SER A  30
None
1.00A 5jwaH-4mh1A:
undetectable
5jwaH-4mh1A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 SER A 178
VAL A 177
GLY A 165
ALA A 164
None
0.93A 5k50A-4mh1A:
undetectable
5k50A-4mh1A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 GLY A 134
GLY A 132
GLN A  -2
VAL A 137
LEU A 129
None
0.99A 5kocB-4mh1A:
undetectable
5kocB-4mh1A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.17A 5l5fH-4mh1A:
undetectable
5l5fI-4mh1A:
undetectable
5l5fH-4mh1A:
19.34
5l5fI-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.17A 5l5fV-4mh1A:
undetectable
5l5fW-4mh1A:
undetectable
5l5fV-4mh1A:
19.34
5l5fW-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.19A 5l66H-4mh1A:
undetectable
5l66I-4mh1A:
undetectable
5l66H-4mh1A:
19.34
5l66I-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
5 / 12 SER A 152
ALA A 217
GLY A 216
THR A 215
THR A 235
None
1.19A 5l66V-4mh1A:
undetectable
5l66W-4mh1A:
undetectable
5l66V-4mh1A:
19.34
5l66W-4mh1A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 GLY A 134
LEU A 129
HIS A  90
None
0.65A 5u63A-4mh1A:
undetectable
5u63A-4mh1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
3 / 3 GLY A 134
LEU A 129
HIS A  90
None
0.65A 5u63B-4mh1A:
undetectable
5u63B-4mh1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 5unvA-4mh1A:
undetectable
5unvB-4mh1A:
undetectable
5unvA-4mh1A:
21.16
5unvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.39A 5unvA-4mh1A:
undetectable
5unvB-4mh1A:
undetectable
5unvA-4mh1A:
21.16
5unvB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 5uo2A-4mh1A:
undetectable
5uo2B-4mh1A:
undetectable
5uo2A-4mh1A:
21.09
5uo2B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 5uo8A-4mh1A:
undetectable
5uo8B-4mh1A:
undetectable
5uo8A-4mh1A:
22.80
5uo8B-4mh1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 5uo8C-4mh1A:
undetectable
5uo8D-4mh1A:
undetectable
5uo8C-4mh1A:
22.80
5uo8D-4mh1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.31A 5uocA-4mh1A:
0.0
5uocB-4mh1A:
0.0
5uocA-4mh1A:
22.80
5uocB-4mh1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 5uocC-4mh1A:
undetectable
5uocD-4mh1A:
0.0
5uocC-4mh1A:
22.80
5uocD-4mh1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 5vukA-4mh1A:
undetectable
5vukB-4mh1A:
undetectable
5vukA-4mh1A:
21.16
5vukB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 5vulA-4mh1A:
undetectable
5vulB-4mh1A:
undetectable
5vulA-4mh1A:
21.16
5vulB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 5vumA-4mh1A:
undetectable
5vumB-4mh1A:
undetectable
5vumA-4mh1A:
21.16
5vumB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 5vumA-4mh1A:
undetectable
5vumB-4mh1A:
undetectable
5vumA-4mh1A:
21.16
5vumB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 5vunA-4mh1A:
undetectable
5vunB-4mh1A:
undetectable
5vunA-4mh1A:
21.16
5vunB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 5vunA-4mh1A:
undetectable
5vunB-4mh1A:
undetectable
5vunA-4mh1A:
21.16
5vunB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 5vuoA-4mh1A:
undetectable
5vuoB-4mh1A:
undetectable
5vuoA-4mh1A:
21.16
5vuoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 5vuoA-4mh1A:
undetectable
5vuoB-4mh1A:
undetectable
5vuoA-4mh1A:
21.16
5vuoB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 5vupA-4mh1A:
undetectable
5vupB-4mh1A:
undetectable
5vupA-4mh1A:
21.16
5vupB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 5vuqA-4mh1A:
undetectable
5vuqB-4mh1A:
undetectable
5vuqA-4mh1A:
21.16
5vuqB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.40A 5vuqA-4mh1A:
undetectable
5vuqB-4mh1A:
undetectable
5vuqA-4mh1A:
21.16
5vuqB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 5vurA-4mh1A:
undetectable
5vurB-4mh1A:
undetectable
5vurA-4mh1A:
21.16
5vurB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 5vutA-4mh1A:
undetectable
5vutB-4mh1A:
undetectable
5vutA-4mh1A:
21.16
5vutB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 5vuuA-4mh1A:
undetectable
5vuuB-4mh1A:
undetectable
5vuuA-4mh1A:
21.16
5vuuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.38A 5vuuA-4mh1A:
undetectable
5vuuB-4mh1A:
undetectable
5vuuA-4mh1A:
21.16
5vuuB-4mh1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 5vuyA-4mh1A:
undetectable
5vuyB-4mh1A:
undetectable
5vuyA-4mh1A:
21.09
5vuyB-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 5vuzA-4mh1A:
undetectable
5vuzB-4mh1A:
undetectable
5vuzA-4mh1A:
21.09
5vuzB-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.41A 5vv0A-4mh1A:
undetectable
5vv0B-4mh1A:
undetectable
5vv0A-4mh1A:
20.91
5vv0B-4mh1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.39A 5vv1A-4mh1A:
undetectable
5vv1B-4mh1A:
undetectable
5vv1A-4mh1A:
21.09
5vv1B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 5vv2A-4mh1A:
undetectable
5vv2B-4mh1A:
undetectable
5vv2A-4mh1A:
21.09
5vv2B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.44A 5vv2A-4mh1A:
undetectable
5vv2B-4mh1A:
undetectable
5vv2A-4mh1A:
21.09
5vv2B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 5vv5A-4mh1A:
undetectable
5vv5B-4mh1A:
undetectable
5vv5A-4mh1A:
21.09
5vv5B-4mh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 5 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.33A 5vvdA-4mh1A:
0.0
5vvdB-4mh1A:
0.0
5vvdA-4mh1A:
22.80
5vvdB-4mh1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 6 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.40A 6auqA-4mh1A:
undetectable
6auqB-4mh1A:
undetectable
6auqA-4mh1A:
11.17
6auqB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 6aurA-4mh1A:
undetectable
6aurB-4mh1A:
undetectable
6aurA-4mh1A:
11.17
6aurB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.44A 6aurA-4mh1A:
undetectable
6aurB-4mh1A:
undetectable
6aurA-4mh1A:
11.17
6aurB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 6ausA-4mh1A:
undetectable
6ausB-4mh1A:
undetectable
6ausA-4mh1A:
11.17
6ausB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 6ausA-4mh1A:
undetectable
6ausB-4mh1A:
undetectable
6ausA-4mh1A:
11.17
6ausB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 6autA-4mh1A:
undetectable
6autB-4mh1A:
undetectable
6autA-4mh1A:
11.17
6autB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 6auvA-4mh1A:
undetectable
6auvB-4mh1A:
undetectable
6auvA-4mh1A:
11.17
6auvB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.41A 6auwA-4mh1A:
undetectable
6auwB-4mh1A:
undetectable
6auwA-4mh1A:
11.17
6auwB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.42A 6auwA-4mh1A:
undetectable
6auwB-4mh1A:
undetectable
6auwA-4mh1A:
11.17
6auwB-4mh1A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 6auyA-4mh1A:
undetectable
6auyB-4mh1A:
undetectable
6auyA-4mh1A:
10.88
6auyB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.42A 6auzA-4mh1A:
undetectable
6auzB-4mh1A:
undetectable
6auzA-4mh1A:
10.88
6auzB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 6av0A-4mh1A:
undetectable
6av0B-4mh1A:
undetectable
6av0A-4mh1A:
10.88
6av0B-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 6av1A-4mh1A:
undetectable
6av1B-4mh1A:
undetectable
6av1A-4mh1A:
10.88
6av1B-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.45A 6av3A-4mh1A:
undetectable
6av3B-4mh1A:
undetectable
6av3A-4mh1A:
10.88
6av3B-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 6av4A-4mh1A:
undetectable
6av4B-4mh1A:
undetectable
6av4A-4mh1A:
10.88
6av4B-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.44A 6av5A-4mh1A:
undetectable
6av5B-4mh1A:
undetectable
6av5A-4mh1A:
10.88
6av5B-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.33A 6av6A-4mh1A:
undetectable
6av6B-4mh1A:
undetectable
6av6A-4mh1A:
12.15
6av6B-4mh1A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.35A 6av6A-4mh1A:
undetectable
6av6B-4mh1A:
undetectable
6av6A-4mh1A:
12.15
6av6B-4mh1A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 6cicA-4mh1A:
undetectable
6cicB-4mh1A:
undetectable
6cicA-4mh1A:
10.88
6cicB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.44A 6cicA-4mh1A:
undetectable
6cicB-4mh1A:
undetectable
6cicA-4mh1A:
10.88
6cicB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 ARG A 385
TRP A 387
TRP A 218
PHE A 286
None
1.43A 6cidA-4mh1A:
undetectable
6cidB-4mh1A:
undetectable
6cidA-4mh1A:
10.88
6cidB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TRP A 218
PHE A 286
ARG A 385
TRP A 387
None
1.43A 6cidA-4mh1A:
undetectable
6cidB-4mh1A:
undetectable
6cidA-4mh1A:
10.88
6cidB-4mh1A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigeni
um
vulgare)
4 / 7 TYR A  27
GLU A  25
ASP A 224
GLU A 335
None
1.27A 6mn5B-4mh1A:
undetectable
6mn5B-4mh1A:
10.63