SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mhh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 149
 None
 1.29A 1dsdC-4mhhH:
undetectable		 1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.27A 1dsdC-4mhhH:
undetectable		 1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 149
 None
 1.29A 1dsdC-4mhhH:
undetectable		 1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.27A 1dsdC-4mhhH:
undetectable		 1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.42A 2y03A-4mhhH:
undetectable		 2y03A-4mhhH:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.43A 2y03B-4mhhH:
undetectable		 2y03B-4mhhH:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		5 / 10 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.46A 4ldoA-4mhhH:
undetectable		 4ldoA-4mhhH:
19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 178
ASP H 183
 None
 0.77A 5mthA-4mhhH:
28.2		 5mthA-4mhhH:
81.45