SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 ALA A 595
VAL A 453
TRP A 451
None
0.77A 1c4dC-4mifA:
undetectable
1c4dD-4mifA:
undetectable
1c4dC-4mifA:
2.22
1c4dD-4mifA:
2.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 THR A 598
THR A 600
PRO A 597
FDA  A 801 (-3.4A)
None
FDA  A 801 (-4.1A)
0.80A 1dscC-4mifA:
undetectable
1dscC-4mifA:
1.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 4 THR A 600
LEU A 599
LEU A 242
GLN A 440
None
1.26A 1fbmA-4mifA:
undetectable
1fbmA-4mifA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 PRO A  75
ILE A  24
GLY A  22
GLY A 153
ALA A 257
None
FDA  A 801 (-3.7A)
FDA  A 801 (-3.2A)
None
None
1.06A 1nv8A-4mifA:
2.9
1nv8A-4mifA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 GLU A 254
HIS A 256
HIS A 245
None
0.59A 1oe2A-4mifA:
undetectable
1oe2A-4mifA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 ASP A 412
LYS A 417
ARG A 420
None
1.05A 1ra8A-4mifA:
undetectable
1ra8A-4mifA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 PRO A  75
ILE A  24
GLY A  22
GLY A 153
ALA A 257
None
FDA  A 801 (-3.7A)
FDA  A 801 (-3.2A)
None
None
1.01A 1sg9B-4mifA:
2.8
1sg9B-4mifA:
19.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 6 THR A 160
GLN A 454
PHE A 480
HIS A 553
ASN A 596
FDA  A 801 (-3.4A)
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.24A 1tt0A-4mifA:
48.1
1tt0A-4mifA:
40.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 6 THR A 160
GLN A 454
PHE A 480
HIS A 553
ASN A 596
FDA  A 801 (-3.4A)
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.21A 1tt0B-4mifA:
48.1
1tt0B-4mifA:
40.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 6 THR A 160
GLN A 454
PHE A 480
HIS A 553
ASN A 596
FDA  A 801 (-3.4A)
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.24A 1tt0C-4mifA:
48.8
1tt0C-4mifA:
40.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 6 THR A 160
GLN A 454
PHE A 480
HIS A 553
ASN A 596
FDA  A 801 (-3.4A)
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.24A 1tt0D-4mifA:
48.8
1tt0D-4mifA:
40.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 CYH A 560
PHE A  28
ALA A 608
ILE A 203
ILE A 204
None
1.26A 2bjfA-4mifA:
undetectable
2bjfA-4mifA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 8 ASP A 458
GLU A 438
HIS A 456
LEU A 242
None
1.09A 2q0iA-4mifA:
undetectable
2q0iA-4mifA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 LEU A 262
ALA A  29
THR A 279
PHE A  50
ARG A 272
None
1.25A 2qo4A-4mifA:
undetectable
2qo4A-4mifA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 LEU A 262
ALA A  29
VAL A  39
THR A 279
ARG A 272
None
1.41A 2qo4A-4mifA:
undetectable
2qo4A-4mifA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 LEU A 262
ALA A  29
THR A 279
PHE A  50
ARG A 272
None
1.26A 2qo6A-4mifA:
undetectable
2qo6A-4mifA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 VAL A 148
SER A 101
ARG A 150
PRO A 506
None
1.08A 2v41E-4mifA:
undetectable
2v41F-4mifA:
undetectable
2v41E-4mifA:
16.40
2v41F-4mifA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 8 VAL A 148
SER A 101
ARG A 150
PRO A 506
None
1.09A 2v41G-4mifA:
undetectable
2v41H-4mifA:
undetectable
2v41G-4mifA:
16.40
2v41H-4mifA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 6 TYR A 477
PRO A 439
ILE A 432
LEU A 399
None
1.18A 2wekB-4mifA:
undetectable
2wekB-4mifA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 GLY A  20
VAL A  42
ILE A  44
ALA A 331
VAL A 340
FDA  A 801 (-3.4A)
None
FDA  A 801 (-3.7A)
None
None
0.62A 3fpjA-4mifA:
2.7
3fpjA-4mifA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 604
PHE A  28
GLY A  25
ALA A 331
THR A 337
None
1.33A 3ld6A-4mifA:
undetectable
3ld6A-4mifA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 604
PHE A  28
GLY A  25
ALA A 331
THR A 337
None
1.36A 3ld6B-4mifA:
undetectable
3ld6B-4mifA:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 6 GLN A 454
PHE A 480
HIS A 553
ASN A 596
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.26A 3lskB-4mifA:
48.0
3lskB-4mifA:
40.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 6 GLN A 454
PHE A 480
HIS A 553
ASN A 596
None
None
FDA  A 801 ( 4.8A)
FDA  A 801 (-4.1A)
0.31A 3lskD-4mifA:
50.7
3lskD-4mifA:
40.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 6 PHE A 275
GLU A  43
VAL A 152
ARG A 272
None
FDA  A 801 (-2.7A)
None
None
1.43A 3n5pA-4mifA:
undetectable
3n5pB-4mifA:
undetectable
3n5pA-4mifA:
21.11
3n5pB-4mifA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 5 ALA A 145
GLU A 385
GLU A 146
ALA A 551
None
1.21A 3r9tC-4mifA:
undetectable
3r9tC-4mifA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 4 GLY A 151
GLY A  45
THR A 279
LEU A 277
FDA  A 801 (-4.5A)
None
None
None
0.93A 3si7C-4mifA:
undetectable
3si7D-4mifA:
undetectable
3si7C-4mifA:
18.58
3si7D-4mifA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 5 ILE A 589
THR A 600
THR A 598
PHE A 166
None
None
FDA  A 801 (-3.4A)
None
1.09A 3snfA-4mifA:
undetectable
3snfA-4mifA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 SER A 156
PRO A  23
GLY A  22
GLY A 153
ASP A  34
None
FDA  A 801 (-3.5A)
FDA  A 801 (-3.2A)
None
None
0.86A 4b17A-4mifA:
2.3
4b17A-4mifA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 SER A 156
PRO A  23
GLY A  22
GLY A 153
ASP A 259
None
FDA  A 801 (-3.5A)
FDA  A 801 (-3.2A)
None
None
1.10A 4b17A-4mifA:
2.3
4b17A-4mifA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 LEU A 262
ILE A 261
ALA A 331
GLY A 584
ALA A  26
None
1.02A 4enhA-4mifA:
undetectable
4enhA-4mifA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 ALA A 336
LEU A 341
GLY A 584
ALA A 605
ALA A 331
FDA  A 801 (-3.4A)
None
None
None
None
1.18A 4pclA-4mifA:
3.0
4pclA-4mifA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 GLU A 178
THR A 442
HIS A 452
None
0.85A 4q15A-4mifA:
2.8
4q15A-4mifA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 GLU A 178
THR A 442
HIS A 452
None
0.87A 4q15B-4mifA:
undetectable
4q15B-4mifA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 8 PHE A 275
SER A  21
THR A 279
ASP A 306
None
FDA  A 801 ( 4.3A)
None
None
1.38A 4qb9D-4mifA:
undetectable
4qb9D-4mifA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 9 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.18A 4qvlH-4mifA:
0.0
4qvlI-4mifA:
0.0
4qvlH-4mifA:
16.99
4qvlI-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 4qvlK-4mifA:
undetectable
4qvlL-4mifA:
undetectable
4qvlK-4mifA:
16.55
4qvlL-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.17A 4qvlV-4mifA:
0.0
4qvlW-4mifA:
0.7
4qvlV-4mifA:
16.99
4qvlW-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.01A 4qvlY-4mifA:
undetectable
4qvlZ-4mifA:
undetectable
4qvlY-4mifA:
16.55
4qvlZ-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 9 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 4qvmK-4mifA:
undetectable
4qvmL-4mifA:
undetectable
4qvmK-4mifA:
16.55
4qvmL-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 4qvmY-4mifA:
undetectable
4qvmZ-4mifA:
undetectable
4qvmY-4mifA:
16.55
4qvmZ-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A  27
ALA A  29
GLY A 585
ALA A 331
THR A 337
None
None
FDA  A 801 (-3.4A)
None
None
1.20A 4qvnV-4mifA:
undetectable
4qvnb-4mifA:
undetectable
4qvnV-4mifA:
16.99
4qvnb-4mifA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A  27
ALA A  29
GLY A 585
ALA A 331
THR A 337
None
None
FDA  A 801 (-3.4A)
None
None
1.19A 4qvnH-4mifA:
undetectable
4qvnN-4mifA:
undetectable
4qvnH-4mifA:
16.99
4qvnN-4mifA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.22A 4qvpH-4mifA:
undetectable
4qvpI-4mifA:
undetectable
4qvpH-4mifA:
16.99
4qvpI-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.01A 4qvpK-4mifA:
undetectable
4qvpL-4mifA:
undetectable
4qvpK-4mifA:
16.55
4qvpL-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.21A 4qvpV-4mifA:
undetectable
4qvpW-4mifA:
undetectable
4qvpV-4mifA:
16.99
4qvpW-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.01A 4qvpY-4mifA:
undetectable
4qvpZ-4mifA:
undetectable
4qvpY-4mifA:
16.55
4qvpZ-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.12A 4qvvH-4mifA:
undetectable
4qvvH-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.11A 4qvvV-4mifA:
undetectable
4qvvV-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.19A 4qvwH-4mifA:
0.0
4qvwI-4mifA:
undetectable
4qvwH-4mifA:
16.99
4qvwI-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.19A 4qvwV-4mifA:
0.0
4qvwW-4mifA:
0.7
4qvwV-4mifA:
16.99
4qvwW-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.13A 4qvyH-4mifA:
undetectable
4qvyH-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.22A 4qvyV-4mifA:
undetectable
4qvyW-4mifA:
undetectable
4qvyV-4mifA:
16.99
4qvyW-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.19A 4qw0H-4mifA:
undetectable
4qw0I-4mifA:
undetectable
4qw0H-4mifA:
16.99
4qw0I-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.22A 4qw0V-4mifA:
undetectable
4qw0W-4mifA:
undetectable
4qw0V-4mifA:
16.99
4qw0W-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.00A 4qw1K-4mifA:
undetectable
4qw1L-4mifA:
undetectable
4qw1K-4mifA:
16.39
4qw1L-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.00A 4qw1Y-4mifA:
undetectable
4qw1Z-4mifA:
undetectable
4qw1Y-4mifA:
16.39
4qw1Z-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.23A 4qw3H-4mifA:
0.0
4qw3I-4mifA:
0.0
4qw3H-4mifA:
16.99
4qw3I-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 4qw3K-4mifA:
undetectable
4qw3L-4mifA:
undetectable
4qw3K-4mifA:
17.06
4qw3L-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.22A 4qw3V-4mifA:
0.0
4qw3W-4mifA:
0.7
4qw3V-4mifA:
16.99
4qw3W-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 4qw3Y-4mifA:
undetectable
4qw3Z-4mifA:
undetectable
4qw3Y-4mifA:
17.06
4qw3Z-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 5 PRO A 239
HIS A 452
TYR A 477
VAL A 475
None
1.30A 4s0vA-4mifA:
2.6
4s0vA-4mifA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 HIS A 256
TRP A 255
PHE A 211
THR A 598
None
None
None
FDA  A 801 (-3.4A)
1.36A 4tzuB-4mifA:
undetectable
4tzuC-4mifA:
undetectable
4tzuB-4mifA:
10.47
4tzuC-4mifA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 GLU A 178
THR A 442
HIS A 452
None
0.82A 4ydqB-4mifA:
undetectable
4ydqB-4mifA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 PRO A 597
GLY A 587
GLU A 146
ILE A 602
GLY A 585
FDA  A 801 (-4.1A)
None
None
None
FDA  A 801 (-3.4A)
1.06A 4yvgA-4mifA:
undetectable
4yvgA-4mifA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.02A 5bxnK-4mifA:
undetectable
5bxnL-4mifA:
undetectable
5bxnK-4mifA:
16.55
5bxnL-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.01A 5bxnY-4mifA:
undetectable
5bxnZ-4mifA:
undetectable
5bxnY-4mifA:
16.55
5bxnZ-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.23A 5cz7H-4mifA:
0.0
5cz7I-4mifA:
undetectable
5cz7H-4mifA:
16.99
5cz7I-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.24A 5cz7V-4mifA:
undetectable
5cz7W-4mifA:
undetectable
5cz7V-4mifA:
16.99
5cz7W-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A 557
GLN A 505
ALA A 334
ALA A 336
ASP A 499
None
None
None
FDA  A 801 (-3.4A)
None
1.19A 5d0xH-4mifA:
undetectable
5d0xI-4mifA:
undetectable
5d0xH-4mifA:
16.99
5d0xI-4mifA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 9 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.00A 5d0xK-4mifA:
undetectable
5d0xL-4mifA:
undetectable
5d0xK-4mifA:
16.55
5d0xL-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.11A 5d0xV-4mifA:
undetectable
5d0xV-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 9 THR A  27
ALA A  29
GLY A 585
GLY A 584
ALA A 331
None
None
FDA  A 801 (-3.4A)
None
None
1.01A 5d0xY-4mifA:
undetectable
5d0xZ-4mifA:
undetectable
5d0xY-4mifA:
16.55
5d0xZ-4mifA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 8 PHE A 266
ILE A  74
PHE A 275
THR A 279
MET A  41
None
1.33A 5esjA-4mifA:
0.9
5esjA-4mifA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 PHE A  17
ASN A 280
LEU A 308
LEU A 277
ALA A  47
None
1.27A 5fctA-4mifA:
undetectable
5fctA-4mifA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
3 / 3 PRO A 180
ARG A 177
GLU A 590
None
1.00A 5j6hA-4mifA:
undetectable
5j6hA-4mifA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 ASP A  48
LEU A 100
GLY A 151
ALA A  99
GLY A  76
None
None
FDA  A 801 (-4.5A)
None
None
1.03A 5kb5A-4mifA:
3.2
5kb5A-4mifA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 9 ALA A 257
ASP A 259
GLY A  22
ILE A  24
THR A 149
None
None
FDA  A 801 (-3.2A)
FDA  A 801 (-3.7A)
None
1.24A 5kr2C-4mifA:
undetectable
5kr2C-4mifA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 10 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.07A 5lf3H-4mifA:
undetectable
5lf3I-4mifA:
undetectable
5lf3H-4mifA:
15.36
5lf3I-4mifA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.05A 5lf7H-4mifA:
undetectable
5lf7I-4mifA:
undetectable
5lf7H-4mifA:
15.36
5lf7I-4mifA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A  27
ALA A  29
GLY A 585
ALA A 331
THR A 337
None
None
FDA  A 801 (-3.4A)
None
None
1.20A 5lf7H-4mifA:
undetectable
5lf7N-4mifA:
undetectable
5lf7H-4mifA:
15.36
5lf7N-4mifA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 11 THR A 149
CYH A 103
ALA A 334
GLY A 333
ALA A 336
None
None
None
FDA  A 801 ( 3.7A)
FDA  A 801 (-3.4A)
1.04A 5lf7V-4mifA:
undetectable
5lf7W-4mifA:
undetectable
5lf7V-4mifA:
15.36
5lf7W-4mifA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 GLY A 549
GLY A 144
GLU A 385
ASN A 586
None
None
None
FDA  A 801 (-3.3A)
0.78A 5ybbB-4mifA:
undetectable
5ybbB-4mifA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 HIS A 256
TRP A 255
PHE A 211
THR A 598
None
None
None
FDA  A 801 (-3.4A)
1.36A 5yizk-4mifA:
0.0
5yizt-4mifA:
undetectable
5yizk-4mifA:
9.01
5yizt-4mifA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 THR A 598
HIS A 256
TRP A 255
PHE A 211
FDA  A 801 (-3.4A)
None
None
None
1.37A 5yj1G-4mifA:
0.0
5yj1Y-4mifA:
undetectable
5yj1G-4mifA:
10.64
5yj1Y-4mifA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 6 ARG A 498
PRO A 506
GLN A 339
ILE A 371
None
1.39A 6ef6A-4mifA:
undetectable
6ef6A-4mifA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A  27
ALA A  29
GLY A 585
ALA A 331
THR A 337
None
None
FDA  A 801 (-3.4A)
None
None
1.18A 6hwdV-4mifA:
undetectable
6hwdb-4mifA:
undetectable
6hwdV-4mifA:
8.76
6hwdb-4mifA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
5 / 12 THR A  27
ALA A  29
GLY A 585
ALA A 331
THR A 337
None
None
FDA  A 801 (-3.4A)
None
None
1.19A 6hwdH-4mifA:
undetectable
6hwdN-4mifA:
undetectable
6hwdH-4mifA:
8.76
6hwdN-4mifA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
4mif PYRANOSE 2-OXIDASE
(Phanerochaete
chrysosporium)
4 / 7 ILE A 323
GLU A 305
HIS A 281
VAL A  42
None
1.00A 6j20A-4mifA:
undetectable
6j20A-4mifA:
21.83