SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 265
ALA A 264
LEU A 146
ALA A 147
 None
 1.08A 1fbyA-4mijA:
undetectable		 1fbyA-4mijA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 265
ALA A 264
LEU A 146
ALA A 147
 None
 1.03A 1xdkE-4mijA:
undetectable		 1xdkE-4mijA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		4 / 6 VAL A  95
PHE A 148
PRO A 240
THR A 111
 None
 1.43A 2q6oB-4mijA:
undetectable		 2q6oB-4mijA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ARG A 174
TYR A 197
GLN A 177
HIS A  39
VAL A  95
 GTR  A 405 (-3.0A)
GTR  A 405 ( 3.7A)
None
ADA  A 406 ( 4.0A)
None
 1.43A 2vavC-4mijA:
0.0		 2vavC-4mijA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 11 SER A 237
HIS A 236
ASN A 214
GLU A 213
GLU A 241
 None
None
GTR  A 405 ( 3.0A)
CL  A 404 (-3.6A)
GTR  A 405 ( 2.9A)
 1.31A 4fevE-4mijA:
undetectable		 4fevE-4mijA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 11 ASN A 214
GLU A 213
GLU A 241
SER A 237
HIS A 236
 GTR  A 405 ( 3.0A)
CL  A 404 (-3.6A)
GTR  A 405 ( 2.9A)
None
None
 1.29A 4fewE-4mijA:
0.1
4fewF-4mijA:
0.8		 4fewE-4mijA:
23.14
4fewF-4mijA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 10 SER A 237
HIS A 236
ASN A 214
GLU A 213
GLU A 241
 None
None
GTR  A 405 ( 3.0A)
CL  A 404 (-3.6A)
GTR  A 405 ( 2.9A)
 1.29A 4gkhG-4mijA:
0.4
4gkhH-4mijA:
0.5		 4gkhG-4mijA:
23.14
4gkhH-4mijA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 11 SER A 237
HIS A 236
ASN A 214
GLU A 213
GLU A 241
 None
None
GTR  A 405 ( 3.0A)
CL  A 404 (-3.6A)
GTR  A 405 ( 2.9A)
 1.33A 4gkiC-4mijA:
0.5
4gkiD-4mijA:
0.5		 4gkiC-4mijA:
23.14
4gkiD-4mijA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 10 SER A 237
HIS A 236
ASN A 214
GLU A 213
GLU A 241
 None
None
GTR  A 405 ( 3.0A)
CL  A 404 (-3.6A)
GTR  A 405 ( 2.9A)
 1.31A 4gkiG-4mijA:
0.9
4gkiH-4mijA:
0.2		 4gkiG-4mijA:
23.14
4gkiH-4mijA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 265
ALA A 264
LEU A 146
ALA A 147
 None
 0.97A 4nqaH-4mijA:
undetectable		 4nqaH-4mijA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		4 / 7 PRO A 113
GLU A 235
TRP A 276
ASP A 277
 None
 1.15A 4uacA-4mijA:
6.3		 4uacA-4mijA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		3 / 3 ASP A  37
ARG A 174
ARG A 154
 None
GTR  A 405 (-3.0A)
ADA  A 406 ( 3.0A)
 0.96A 4x5iA-4mijA:
undetectable		 4x5iA-4mijA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 265
ALA A 264
LEU A 146
ALA A 147
 None
 1.00A 5uanA-4mijA:
undetectable		 5uanA-4mijA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 265
ALA A 264
LEU A 146
ALA A 147
 None
 1.08A 6a5zD-4mijA:
undetectable		 6a5zD-4mijA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mij TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Polaromonas
sp.
JS666) 		5 / 12 ILE A 261
ALA A 264
ALA A 265
LEU A  57
ILE A 249
 None
 0.95A 6a5zL-4mijA:
undetectable		 6a5zL-4mijA:
12.72