SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		5 / 12 ILE A 288
GLY A 156
ALA A 112
ASP A 198
LEU A 197
 None
 1.21A 1i9gA-4mj0A:
undetectable		 1i9gA-4mj0A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		5 / 12 LEU A 290
ILE A 288
VAL A 243
LEU A 244
GLY A 251
 None
 0.92A 1uakA-4mj0A:
undetectable		 1uakA-4mj0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		4 / 8 GLY A 251
GLU A 111
ALA A 112
ASN A 217
 None
 0.78A 2dtjA-4mj0A:
undetectable
2dtjB-4mj0A:
undetectable		 2dtjA-4mj0A:
20.30
2dtjB-4mj0A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		4 / 6 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.26A 3lb3A-4mj0A:
undetectable		 3lb3A-4mj0A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		4 / 6 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.26A 3lb3B-4mj0A:
undetectable		 3lb3B-4mj0A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		5 / 7 THR A 218
PRO A 210
ASN A 215
GLY A 222
THR A 223
 None
None
None
GOL  A 405 (-3.8A)
GOL  A 405 (-3.9A)
 1.42A 3tajA-4mj0A:
undetectable		 3tajA-4mj0A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		4 / 5 ASP A  74
PRO A  80
GLU A 206
THR A 170
 None
 1.49A 5uxcA-4mj0A:
undetectable		 5uxcA-4mj0A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		5 / 12 LEU A 290
ILE A 288
VAL A 243
LEU A 244
GLY A 251
 None
 0.88A 5zhmB-4mj0A:
undetectable		 5zhmB-4mj0A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		3 / 3 GLN A 187
TYR A 168
ASN A 167
 None
 0.91A 6dwdC-4mj0A:
undetectable		 6dwdC-4mj0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4mj0 VP1 CAPSID PROTEIN
(Human
polyomavirus
1) 		3 / 3 PHE A  75
ARG A 169
GLN A 187
 None
 0.76A 6g1pB-4mj0A:
undetectable		 6g1pB-4mj0A:
21.29