SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  69
ARG A  86
ALA A  68
ILE A  61
 None
 1.14A 2qhfA-4mj7A:
undetectable		 2qhfA-4mj7A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 THR A  52
LEU A  34
VAL A  35
PHE A  43
CYH A  38
 None
 1.11A 3u9fB-4mj7A:
undetectable
3u9fC-4mj7A:
undetectable		 3u9fB-4mj7A:
18.94
3u9fC-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 THR A  52
VAL A  35
PHE A  84
PHE A  43
CYH A  38
 None
 1.19A 3u9fB-4mj7A:
undetectable
3u9fC-4mj7A:
undetectable		 3u9fB-4mj7A:
18.94
3u9fC-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 11 PHE A  43
CYH A  38
THR A  52
VAL A  35
PHE A  84
 None
 1.15A 3u9fA-4mj7A:
undetectable
3u9fC-4mj7A:
undetectable		 3u9fA-4mj7A:
18.94
3u9fC-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 THR A  52
VAL A  35
PHE A  84
PHE A  43
CYH A  38
 None
 1.13A 3u9fH-4mj7A:
undetectable
3u9fI-4mj7A:
undetectable		 3u9fH-4mj7A:
18.94
3u9fI-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  43
CYH A  38
THR A  52
LEU A  34
VAL A  35
 None
 1.10A 3u9fP-4mj7A:
undetectable
3u9fS-4mj7A:
undetectable		 3u9fP-4mj7A:
18.94
3u9fS-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  43
CYH A  38
THR A  52
VAL A  35
PHE A  84
 None
 1.13A 3u9fP-4mj7A:
undetectable
3u9fS-4mj7A:
undetectable		 3u9fP-4mj7A:
18.94
3u9fS-4mj7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  49
ALA A 120
LEU A 141
THR A  52
LEU A  53
 None
 1.34A 4ltwA-4mj7A:
undetectable		 4ltwA-4mj7A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 118
LEU A  53
ILE A 139
LEU A 138
 None
 0.60A 4mghA-4mj7A:
undetectable		 4mghA-4mj7A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 4mj7 RRNA-PROCESSING
PROTEIN UTP23
(Saccharomyces
cerevisiae) 		5 / 12 MET A  60
LEU A  29
ALA A 120
LEU A 130
LEU A  49
 None
 1.08A 4zn7A-4mj7A:
undetectable		 4zn7A-4mj7A:
21.54