SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 6 MET A  49
VAL A  25
LEU A  26
PHE A  30
 None
 1.13A 1x8vA-4mjdA:
undetectable		 1x8vA-4mjdA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 8 ILE A 100
LEU A  26
ARG A   8
LEU A  14
 None
 0.93A 3ag3N-4mjdA:
undetectable
3ag3W-4mjdA:
undetectable		 3ag3N-4mjdA:
12.00
3ag3W-4mjdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 VAL A  25
LEU A  26
SER A  23
MET A  49
 None
 1.24A 4e1gA-4mjdA:
undetectable		 4e1gA-4mjdA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		3 / 3 ASP A  33
ARG A 104
ASP A  36
 None
 0.83A 4fp9A-4mjdA:
undetectable		 4fp9A-4mjdA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  10
 None
 1.21A 4oltA-4mjdA:
undetectable		 4oltA-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.26A 4oltA-4mjdA:
undetectable		 4oltA-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.27A 4oltA-4mjdA:
undetectable		 4oltA-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  10
 None
 1.21A 4oltB-4mjdA:
undetectable		 4oltB-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.28A 4oltB-4mjdA:
undetectable		 4oltB-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.30A 4oltB-4mjdA:
undetectable		 4oltB-4mjdA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  10
 None
 1.14A 4qwpA-4mjdA:
undetectable		 4qwpA-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.24A 4qwpA-4mjdA:
undetectable		 4qwpA-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.29A 4qwpA-4mjdA:
undetectable		 4qwpA-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  10
 None
 1.17A 4qwpB-4mjdA:
undetectable		 4qwpB-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.23A 4qwpB-4mjdA:
undetectable		 4qwpB-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 5 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.28A 4qwpB-4mjdA:
undetectable		 4qwpB-4mjdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 7 ARG A  34
THR A 105
ASP A  91
TYR A  11
 None
 1.10A 5hwaA-4mjdA:
undetectable		 5hwaA-4mjdA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 7 ILE A 100
LEU A  26
ARG A   8
LEU A  14
 None
 0.98A 5iy5A-4mjdA:
undetectable
5iy5J-4mjdA:
undetectable		 5iy5A-4mjdA:
12.00
5iy5J-4mjdA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 8 LEU A  14
MET A  49
LEU A  26
ILE A 100
 None
 0.97A 5mzjA-4mjdA:
undetectable		 5mzjA-4mjdA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 8 ILE A 100
LEU A  26
ARG A   8
LEU A  14
 None
 0.90A 5xdxN-4mjdA:
undetectable
5xdxW-4mjdA:
undetectable		 5xdxN-4mjdA:
12.00
5xdxW-4mjdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747
(Halomicrobium
mukohataei) 		4 / 7 ILE A 100
LEU A  26
ARG A   8
LEU A  14
 None
 0.82A 6nmfA-4mjdA:
undetectable
6nmfJ-4mjdA:
undetectable		 6nmfA-4mjdA:
12.00
6nmfJ-4mjdA:
18.92