SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_D_URFD999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	4mje	PROBABLE GLUTAREDOXIN SSR2061 (Synechocystis sp. PCC 6803)	4 / 4	MET A 58 ALA A 54 TYR A 46 ILE A 48	None	1.19A	1upfD-4mjeA: undetectable	1upfD-4mjeA: 17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	4mje	PROBABLE GLUTAREDOXIN SSR2061 (Synechocystis sp. PCC 6803)	4 / 6	SER A 67 PHE A 28 ASP A 82 PRO A 27	None SO4 A 102 (-4.1A) SO4 A 102 (-3.6A) None	1.45A	3jqaC-4mjeA: undetectable	3jqaC-4mjeA: 18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	4mje	PROBABLE GLUTAREDOXIN SSR2061 (Synechocystis sp. PCC 6803)	4 / 6	SER A 67 PHE A 28 ASP A 82 PRO A 27	None SO4 A 102 (-4.1A) SO4 A 102 (-3.6A) None	1.48A	3jqaD-4mjeA: undetectable	3jqaD-4mjeA: 18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_D_SORD1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	4mje	PROBABLE GLUTAREDOXIN SSR2061 (Synechocystis sp. PCC 6803)	4 / 6	LYS A 65 GLY A 79 GLY A 80 ASP A 83	None None SO4 A 102 (-3.5A) None	0.92A	5a06D-4mjeA: undetectable	5a06D-4mjeA: 14.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UPF_D_URFD999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","4mje","PROBABLE GLUTAREDOXIN SSR2061","Synechocystis sp. PCC 6803",4,"MET A  58;ALA A  54;TYR A  46;ILE A  48","None","1.19A","1upfD-4mjeA:undetectable","1upfD-4mjeA:17.56"],["3JQA_C_DX4C270_0","PTERIDINE REDUCTASE 1","4mje","PROBABLE GLUTAREDOXIN SSR2061","Synechocystis sp. PCC 6803",4,"SER A  67;PHE A  28;ASP A  82;PRO A  27","None;SO4 A 102 (-4.1A);SO4 A 102 (-3.6A);None","1.45A","3jqaC-4mjeA:undetectable","3jqaC-4mjeA:18.77"],["3JQA_D_DX4D270_0","PTERIDINE REDUCTASE 1","4mje","PROBABLE GLUTAREDOXIN SSR2061","Synechocystis sp. PCC 6803",4,"SER A  67;PHE A  28;ASP A  82;PRO A  27","None;SO4 A 102 (-4.1A);SO4 A 102 (-3.6A);None","1.48A","3jqaD-4mjeA:undetectable","3jqaD-4mjeA:18.77"],["5A06_D_SORD1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","4mje","PROBABLE GLUTAREDOXIN SSR2061","Synechocystis sp. PCC 6803",4,"LYS A  65;GLY A  79;GLY A  80;ASP A  83","None;None;SO4 A 102 (-3.5A);None","0.92A","5a06D-4mjeA:undetectable","5a06D-4mjeA:14.51"]]