SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		5 / 11 LEU A 142
LEU A 236
THR A 237
THR A 115
TRP A 139
 None
None
CL  A 314 ( 4.0A)
CL  A 314 ( 3.8A)
None
 1.27A 1dmyA-4mjfA:
undetectable		 1dmyA-4mjfA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 5 GLY A 157
TRP A 159
ARG A 154
LEU A 158
 None
 1.06A 2j2pD-4mjfA:
undetectable
2j2pF-4mjfA:
undetectable		 2j2pD-4mjfA:
19.15
2j2pF-4mjfA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 5 GLY A 274
TRP A 276
ARG A 271
LEU A 275
 SO4  A 303 ( 4.8A)
None
SO4  A 303 (-3.7A)
None
 1.18A 2j2pD-4mjfA:
undetectable
2j2pF-4mjfA:
undetectable		 2j2pD-4mjfA:
19.15
2j2pF-4mjfA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 8 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
CXS  A 300 ( 4.9A)
None
EDO  A 307 ( 3.9A)
 0.72A 3t3sD-4mjfA:
undetectable		 3t3sD-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 8 PHE A 269
PHE A 179
PHE A 186
ALA A 187
 None
 0.82A 3t3sD-4mjfA:
undetectable		 3t3sD-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 7 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
CXS  A 300 ( 4.9A)
None
EDO  A 307 ( 3.9A)
 0.67A 4ejgA-4mjfA:
undetectable		 4ejgA-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 7 PHE A 269
PHE A 179
PHE A 186
ALA A 187
 None
 0.79A 4ejgA-4mjfA:
undetectable		 4ejgA-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 5 LEU A 201
PHE A 203
LEU A 278
PHE A 186
 CL  A 311 ( 4.6A)
None
None
None
 1.14A 5iy5P-4mjfA:
undetectable
5iy5W-4mjfA:
undetectable		 5iy5P-4mjfA:
19.60
5iy5W-4mjfA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4mjf HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 5 LEU A 201
PHE A 203
LEU A 278
PHE A 186
 CL  A 311 ( 4.6A)
None
None
None
 1.18A 5xdxP-4mjfA:
undetectable
5xdxW-4mjfA:
undetectable		 5xdxP-4mjfA:
20.61
5xdxW-4mjfA:
14.29