SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4mjt MONALYSIN
(Pseudomonas
entomophila) 		4 / 5 ASN A 193
ALA A 196
TYR A 213
ALA A 186
 None
 1.35A 3twpD-4mjtA:
undetectable		 3twpD-4mjtA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4mjt MONALYSIN
(Pseudomonas
entomophila) 		5 / 9 ALA A 186
THR A 187
ALA A 189
ILE A 136
GLY A  74
 None
 0.88A 4qvqK-4mjtA:
undetectable
4qvqL-4mjtA:
undetectable		 4qvqK-4mjtA:
22.45
4qvqL-4mjtA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4mjt MONALYSIN
(Pseudomonas
entomophila) 		5 / 9 ALA A 186
THR A 187
ALA A 189
ILE A 136
GLY A  74
 None
 0.89A 4qvqY-4mjtA:
undetectable
4qvqZ-4mjtA:
undetectable		 4qvqY-4mjtA:
22.45
4qvqZ-4mjtA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4mjt MONALYSIN
MONALYSIN
(Pseudomonas
entomophila;
Pseudomonas
entomophila) 		4 / 6 TRP A  83
GLY A  84
THR A  85
SER J  14
 None
 1.11A 5ewuA-4mjtA:
undetectable		 5ewuA-4mjtA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4mjt MONALYSIN
(Pseudomonas
entomophila) 		3 / 3 VAL A 179
ALA A 216
GLN A  95
 None
 0.42A 6gb9A-4mjtA:
undetectable		 6gb9A-4mjtA:
17.88