SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4mkq MONALYSIN
(Pseudomonas
entomophila) 		4 / 5 ASN A 193
ALA A 196
TYR A 213
ALA A 186
 None
 1.34A 3twpD-4mkqA:
undetectable		 3twpD-4mkqA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4mkq MONALYSIN
(Pseudomonas
entomophila) 		5 / 10 TYR A  96
TYR A 176
ILE A 224
THR A  99
ILE A 100
 None
 1.07A 5mzrA-4mkqA:
undetectable		 5mzrA-4mkqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4mkq MONALYSIN
(Pseudomonas
entomophila) 		5 / 10 TYR A  96
TYR A 176
ILE A 224
THR A  99
ILE A 100
 None
 1.12A 5mzrC-4mkqA:
undetectable		 5mzrC-4mkqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4mkq MONALYSIN
(Pseudomonas
entomophila) 		3 / 3 VAL A 179
ALA A 216
GLN A  95
 None
 0.47A 6gb9A-4mkqA:
undetectable		 6gb9A-4mkqA:
17.44