SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mkv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  69
TRP A  70
 None
 0.73A 1av2A-4mkvA:
undetectable
1av2B-4mkvA:
undetectable		 1av2A-4mkvA:
3.79
1av2B-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.83A 1av2C-4mkvA:
undetectable
1av2D-4mkvA:
undetectable		 1av2C-4mkvA:
3.79
1av2D-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.58A 1bdwA-4mkvA:
undetectable
1bdwB-4mkvA:
undetectable		 1bdwA-4mkvA:
3.79
1bdwB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 5 THR A 271
GLU A 204
HIS A 292
HIS A 298
 None
RUB  A 501 (-3.2A)
None
RUB  A 501 ( 4.9A)
 1.47A 1d4fD-4mkvA:
undetectable		 1d4fD-4mkvA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 MET A 387
LEU A 197
GLY A 404
TRP A 462
 None
None
RUB  A 501 (-3.7A)
None
 1.02A 1hrkA-4mkvA:
undetectable		 1hrkA-4mkvA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1jnoA-4mkvA:
undetectable		 1jnoA-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1jnoB-4mkvA:
undetectable		 1jnoB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1jo3A-4mkvA:
undetectable		 1jo3A-4mkvA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1jo3B-4mkvA:
undetectable		 1jo3B-4mkvA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.80A 1jo4A-4mkvA:
undetectable		 1jo4A-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.80A 1jo4B-4mkvA:
undetectable		 1jo4B-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ARG A 431
GLY A 166
ASP A 396
 None
 0.49A 1kf6A-4mkvA:
undetectable
1kf6B-4mkvA:
undetectable		 1kf6A-4mkvA:
21.19
1kf6B-4mkvA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 7 LEU A 400
MET A 266
TYR A 239
LEU A 197
 None
 1.04A 1kt3A-4mkvA:
undetectable		 1kt3A-4mkvA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.79A 1magA-4mkvA:
undetectable		 1magA-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.79A 1magB-4mkvA:
undetectable		 1magB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.79A 1ng8A-4mkvA:
undetectable		 1ng8A-4mkvA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.79A 1ng8B-4mkvA:
undetectable		 1ng8B-4mkvA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.74A 1nrmA-4mkvA:
undetectable		 1nrmA-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.73A 1nrmB-4mkvA:
undetectable		 1nrmB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1nruA-4mkvA:
undetectable		 1nruA-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.81A 1nruB-4mkvA:
undetectable		 1nruB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 11 LEU A 349
ASP A 347
ILE A 362
GLY A 344
HIS A 310
 None
 1.28A 1s9aA-4mkvA:
undetectable		 1s9aA-4mkvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 LEU A 349
ASP A 347
ILE A 362
GLY A 344
HIS A 310
 None
 1.26A 1s9aB-4mkvA:
undetectable		 1s9aB-4mkvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  69
TRP A  70
 None
 0.75A 1w5uA-4mkvA:
undetectable
1w5uB-4mkvA:
undetectable		 1w5uA-4mkvA:
3.79
1w5uB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.85A 1w5uA-4mkvA:
undetectable
1w5uB-4mkvA:
undetectable		 1w5uA-4mkvA:
3.79
1w5uB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.87A 1w5uC-4mkvA:
undetectable
1w5uD-4mkvA:
undetectable		 1w5uC-4mkvA:
3.79
1w5uD-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 GLY A 344
SER A 359
ASP A 347
ARG A 350
ALA A 328
 None
 1.10A 2bm9B-4mkvA:
undetectable		 2bm9B-4mkvA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 ARG A 187
GLY A 186
THR A 200
ILE A 174
 None
 0.81A 2f9wA-4mkvA:
undetectable
2f9wB-4mkvA:
undetectable		 2f9wA-4mkvA:
22.73
2f9wB-4mkvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  66
ALA A  15
VAL A  17
 None
 0.80A 2izqA-4mkvA:
undetectable
2izqB-4mkvA:
undetectable		 2izqA-4mkvA:
3.79
2izqB-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.65A 2izqC-4mkvA:
undetectable
2izqD-4mkvA:
undetectable		 2izqC-4mkvA:
3.79
2izqD-4mkvA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 7 VAL A 113
THR A 114
PHE A 117
THR A 118
 None
 1.11A 2kotA-4mkvA:
undetectable		 2kotA-4mkvA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 HIS A 292
ILE A 382
LEU A 400
GLY A 171
ALA A 378
 None
 1.00A 2oc8A-4mkvA:
undetectable		 2oc8A-4mkvA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 SER A 321
HIS A 292
ASP A 203
 None
None
RUB  A 501 (-3.2A)
 0.71A 2oxtA-4mkvA:
undetectable		 2oxtA-4mkvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC
(Pisum
sativum;
Pisum
sativum) 		3 / 3 LEU S  18
PRO S  19
ARG A 435
 None
 0.56A 2qd4B-4mkvS:
undetectable		 2qd4B-4mkvS:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC
(Pisum
sativum;
Pisum
sativum) 		3 / 3 LEU S  18
PRO S  19
ARG A 435
 None
 0.55A 2qd5A-4mkvS:
undetectable		 2qd5A-4mkvS:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 7 THR A 342
GLY A 337
LEU A 390
PHE A 394
 None
 0.94A 2vl2B-4mkvA:
undetectable		 2vl2B-4mkvA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 MET A 309
VAL A 121
TYR A 144
PHE A 274
 None
 0.97A 2wekA-4mkvA:
undetectable		 2wekA-4mkvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 MET A 309
VAL A 121
TYR A 144
PHE A 274
 None
 0.93A 2wekB-4mkvA:
undetectable		 2wekB-4mkvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC
(Pisum
sativum) 		5 / 10 GLU A 234
LYS A 236
PRO A 263
ARG A 167
LYS S  11
 None
 1.28A 3bjwD-4mkvA:
undetectable		 3bjwD-4mkvA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 PHE A 394
GLY A 171
ASP A 396
ILE A 393
PRO A 376
 None
 1.21A 3eeoA-4mkvA:
undetectable		 3eeoA-4mkvA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		6 / 12 ALA A 458
GLY A 416
GLY A 408
ASN A 420
HIS A 383
VAL A 384
 None
 1.20A 3f8wA-4mkvA:
undetectable		 3f8wA-4mkvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 ALA A 458
GLY A 416
GLY A 408
ASN A 420
VAL A 384
 None
 1.14A 3f8wC-4mkvA:
undetectable		 3f8wC-4mkvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 4 ARG A 431
ASP A 397
ASP A 396
PRO A 168
 None
 1.44A 3fgrB-4mkvA:
undetectable		 3fgrB-4mkvA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ILE A 301
PHE A 117
HIS A 310
 None
 0.75A 3h0aA-4mkvA:
undetectable		 3h0aA-4mkvA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 LEU A 349
ASP A 347
ILE A 362
GLY A 344
HIS A 310
 None
 1.28A 3hgiA-4mkvA:
undetectable		 3hgiA-4mkvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.82A 3l8lA-4mkvA:
undetectable
3l8lB-4mkvA:
undetectable		 3l8lA-4mkvA:
3.79
3l8lB-4mkvA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.67A 3l8lA-4mkvA:
undetectable
3l8lB-4mkvA:
undetectable		 3l8lA-4mkvA:
3.79
3l8lB-4mkvA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.65A 3l8lC-4mkvA:
undetectable
3l8lD-4mkvA:
undetectable		 3l8lC-4mkvA:
3.79
3l8lD-4mkvA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 10 GLY A 329
ALA A 328
GLY A 344
ILE A 341
LEU A 314
 RUB  A 501 ( 4.5A)
None
None
None
None
 0.93A 3ttpA-4mkvA:
undetectable		 3ttpA-4mkvA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 GLY A 166
GLY A 196
ASN A 420
MET A 387
 None
 0.93A 3v3nB-4mkvA:
undetectable		 3v3nB-4mkvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 GLY A 166
GLY A 196
ASN A 420
MET A 387
 None
 0.93A 3v3nC-4mkvA:
undetectable		 3v3nC-4mkvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 5 HIS A 294
LEU A 169
LEU A 400
ASP A 397
 RUB  A 501 ( 4.8A)
None
None
None
 1.30A 4aqlA-4mkvA:
5.9		 4aqlA-4mkvA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC
(Pisum
sativum;
Pisum
sativum) 		4 / 7 GLU A 433
TYR S  32
ARG A 431
GLY A 166
 None
 0.99A 4fgzA-4mkvA:
undetectable		 4fgzA-4mkvA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC
(Pisum
sativum) 		4 / 8 ASN A 420
GLU A 425
TYR S  17
TYR A 165
 None
 1.11A 4mj8A-4mkvA:
undetectable
4mj8C-4mkvA:
undetectable		 4mj8A-4mkvA:
16.89
4mj8C-4mkvA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 9 VAL A 313
ALA A  38
ARG A  41
PHE A 117
ILE A 120
 None
 1.20A 4oknB-4mkvA:
undetectable		 4oknB-4mkvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 8 TYR A 269
THR A 271
HIS A 327
PHE A 345
 None
None
RUB  A 501 (-4.1A)
None
 1.00A 4tzcB-4mkvA:
undetectable
4tzcD-4mkvA:
undetectable		 4tzcB-4mkvA:
13.32
4tzcD-4mkvA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 TYR A 239
GLU A 158
GLY A 237
PRO A 152
LEU A 280
 None
 1.19A 4wcxC-4mkvA:
4.7		 4wcxC-4mkvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 LEU A 280
LEU A 289
ASN A 287
ALA A 257
ALA A 242
 None
 1.24A 4x1iB-4mkvA:
undetectable		 4x1iB-4mkvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 LEU A 280
LEU A 289
ASN A 287
ALA A 257
ALA A 242
 None
 1.05A 4x1iD-4mkvA:
undetectable		 4x1iD-4mkvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 4 LEU A 240
ILE A 225
HIS A 238
VAL A 262
 None
 1.32A 4xyzA-4mkvA:
undetectable		 4xyzA-4mkvA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		5 / 12 GLU A 425
VAL A 418
GLY A 380
THR A 330
LEU A 390
 None
None
RUB  A 501 (-3.3A)
None
None
 1.40A 5esgA-4mkvA:
undetectable		 5esgA-4mkvA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 5 SER A  61
MET A 309
LEU A 135
PHE A  40
 None
 1.25A 5evyX-4mkvA:
undetectable		 5evyX-4mkvA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 6 THR A  26
TYR A  85
TYR A 103
PHE A 364
 None
None
None
PO4  A 502 (-4.8A)
 1.08A 5lrbA-4mkvA:
undetectable		 5lrbA-4mkvA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		4 / 5 ILE A 120
PHE A 108
ARG A  83
THR A  31
 None
 1.29A 5z84N-4mkvA:
undetectable
5z84W-4mkvA:
undetectable		 5z84N-4mkvA:
19.63
5z84W-4mkvA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Pisum
sativum) 		3 / 3 ARG A 159
ARG A 431
ARG A 167
 None
 0.98A 6bplA-4mkvA:
undetectable
6bplB-4mkvA:
undetectable		 6bplA-4mkvA:
10.79
6bplB-4mkvA:
10.79