SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ml9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.92A 1c6yB-4ml9A:
undetectable
1c6yB-4ml9A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.84A 1c6zB-4ml9A:
undetectable
1c6zB-4ml9A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.92A 1fb7A-4ml9A:
undetectable
1fb7A-4ml9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 LYS A  15
LYS A  16
ASP A  19
ALA A  20
None
0.29A 1iwhA-4ml9A:
undetectable
1iwhA-4ml9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 LEU A  30
TYR A 163
ILE A 138
VAL A 149
VAL A 136
None
1.00A 1vptA-4ml9A:
undetectable
1vptA-4ml9A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
1.02A 2b60B-4ml9A:
undetectable
2b60B-4ml9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
6 / 12 GLY A 203
GLY A 237
THR A 202
LEU A 200
GLU A 236
HIS A 166
None
GOL  A 307 ( 4.8A)
None
None
MG  A 301 (-1.9A)
EDO  A 308 (-3.8A)
1.34A 2oxtB-4ml9A:
undetectable
2oxtB-4ml9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 5 VAL A  90
THR A  91
VAL A 106
GLY A 107
None
1.07A 2p2fA-4ml9A:
4.2
2p2fA-4ml9A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 4 VAL A  90
THR A  91
VAL A 106
GLY A 107
None
1.09A 2p2fB-4ml9A:
3.5
2p2fB-4ml9A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
1.00A 2pynA-4ml9A:
undetectable
2pynA-4ml9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 THR A 250
ILE A 218
LEU A 255
ASN A 253
ILE A 239
None
None
None
EDO  A 309 (-3.3A)
None
1.28A 3a50B-4ml9A:
undetectable
3a50B-4ml9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 THR A 250
ILE A 218
LEU A 255
ASN A 253
ILE A 239
None
None
None
EDO  A 309 (-3.3A)
None
1.23A 3a50C-4ml9A:
undetectable
3a50C-4ml9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 THR A 250
ILE A 218
LEU A 255
ASN A 253
ILE A 239
None
None
None
EDO  A 309 (-3.3A)
None
1.25A 3a50E-4ml9A:
undetectable
3a50E-4ml9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 LEU A 120
PHE A 125
HIS A  57
PRO A  55
VAL A  90
None
1.44A 3aqiA-4ml9A:
4.3
3aqiA-4ml9A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 PRO A 180
ALA A 184
ALA A 187
GLU A 220
None
0.66A 3dtuC-4ml9A:
undetectable
3dtuD-4ml9A:
undetectable
3dtuC-4ml9A:
19.40
3dtuD-4ml9A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.96A 3ekxA-4ml9A:
undetectable
3ekxA-4ml9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.97A 3k4vD-4ml9A:
undetectable
3k4vD-4ml9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.88A 3ndtD-4ml9A:
undetectable
3ndtD-4ml9A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.96A 3nduD-4ml9A:
undetectable
3nduD-4ml9A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.95A 3ndwA-4ml9A:
undetectable
3ndwA-4ml9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.94A 3ndxA-4ml9A:
undetectable
3ndxA-4ml9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.94A 3oxcA-4ml9A:
undetectable
3oxcA-4ml9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.97A 3tkgC-4ml9A:
undetectable
3tkgC-4ml9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 HIS A  66
GLU A 114
ASN A  56
GLU A  54
None
None
EDO  A 306 (-3.6A)
EDO  A 306 (-3.8A)
1.32A 3vywA-4ml9A:
2.4
3vywA-4ml9A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 THR A 105
HIS A 139
TYR A 163
TYR A 103
None
MG  A 301 ( 3.7A)
None
None
1.48A 4a3uB-4ml9A:
7.8
4a3uB-4ml9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 THR A 233
GLY A 199
ILE A 164
LEU A 222
None
1.06A 4ac9C-4ml9A:
3.3
4ac9C-4ml9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 THR A 105
HIS A 139
TYR A 163
TYR A 103
None
MG  A 301 ( 3.7A)
None
None
1.45A 4df2A-4ml9A:
11.5
4df2A-4ml9A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 5 SER A  31
GLY A 258
VAL A 264
ASP A 262
None
GOL  A 307 (-3.6A)
None
EDO  A 310 (-3.6A)
1.12A 4eohA-4ml9A:
2.7
4eohA-4ml9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.07A 4feuB-4ml9A:
undetectable
4feuB-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.08A 4feuF-4ml9A:
undetectable
4feuF-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.10A 4fevD-4ml9A:
undetectable
4fevD-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.10A 4fevF-4ml9A:
undetectable
4fevF-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.09A 4fewD-4ml9A:
undetectable
4fewD-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.07A 4fewF-4ml9A:
undetectable
4fewF-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.14A 4fexB-4ml9A:
undetectable
4fexB-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.07A 4gkhB-4ml9A:
undetectable
4gkhB-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.11A 4gkhF-4ml9A:
undetectable
4gkhF-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.09A 4gkhG-4ml9A:
undetectable
4gkhG-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.08A 4gkhC-4ml9A:
undetectable
4gkhK-4ml9A:
undetectable
4gkhC-4ml9A:
23.79
4gkhK-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.09A 4gkiA-4ml9A:
undetectable
4gkiA-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.06A 4gkiC-4ml9A:
undetectable
4gkiC-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 8 ASP A 262
ASN A  56
GLU A  76
ASP A  37
EDO  A 310 (-3.6A)
EDO  A 306 (-3.6A)
EDO  A 306 (-3.1A)
None
1.11A 4gkiE-4ml9A:
undetectable
4gkiG-4ml9A:
undetectable
4gkiE-4ml9A:
23.79
4gkiG-4ml9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
3 / 3 GLU A 114
ARG A  79
HIS A  57
None
0.79A 4kf9A-4ml9A:
undetectable
4kf9A-4ml9A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 11 LEU A 120
PHE A 125
HIS A  57
PRO A  55
VAL A  90
None
1.43A 4mk4B-4ml9A:
4.2
4mk4B-4ml9A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 GLY A 132
ALA A 133
ASP A 134
PRO A 109
ILE A 128
None
0.99A 4njvA-4ml9A:
undetectable
4njvA-4ml9A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 LEU A 225
HIS A 139
HIS A 137
GLU A 236
None
MG  A 301 ( 3.7A)
MG  A 301 ( 3.2A)
MG  A 301 (-1.9A)
0.94A 4pahA-4ml9A:
undetectable
4pahA-4ml9A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 HIS A 137
GLY A 107
PHE A 112
MET A  72
GLY A  33
MG  A 301 ( 3.2A)
None
EDO  A 306 (-4.5A)
None
None
1.18A 4qa2A-4ml9A:
undetectable
4qa2A-4ml9A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 ASP A 249
THR A 233
PRO A 232
VAL A 226
None
None
EDO  A 309 (-3.2A)
None
1.14A 4yoaA-4ml9A:
undetectable
4yoaA-4ml9A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
3 / 5 GLY A 107
GLY A 111
GLU A 114
None
0.52A 4z2eA-4ml9A:
undetectable
4z2eD-4ml9A:
2.0
4z2eA-4ml9A:
20.83
4z2eD-4ml9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 ILE A 138
GLU A 119
GLY A 110
GLY A 111
None
0.74A 5a06B-4ml9A:
undetectable
5a06B-4ml9A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 GLU A   7
LEU A  14
ARG A  10
ARG A  11
None
1.21A 5l6eA-4ml9A:
undetectable
5l6eB-4ml9A:
undetectable
5l6eA-4ml9A:
22.18
5l6eB-4ml9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 7 PHE A 247
THR A  32
ILE A 239
GLY A 258
None
GOL  A 307 (-3.6A)
None
GOL  A 307 (-3.6A)
1.00A 5nzyA-4ml9A:
undetectable
5nzyA-4ml9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
5 / 12 LEU A 120
VAL A 149
VAL A 160
ASP A 161
GLY A 135
None
0.86A 5x24A-4ml9A:
undetectable
5x24A-4ml9A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 4 PRO A  58
LEU A  62
VAL A  78
ARG A  79
EDO  A 306 ( 4.8A)
EDO  A 310 (-4.1A)
None
None
1.42A 6fgdA-4ml9A:
undetectable
6fgdA-4ml9A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)
4ml9 UNCHARACTERIZED
PROTEIN

(Sebaldella
termitidis)
4 / 6 LEU A 225
HIS A 139
HIS A 137
GLU A 236
None
MG  A 301 ( 3.7A)
MG  A 301 ( 3.2A)
MG  A 301 (-1.9A)
0.99A 6pahA-4ml9A:
undetectable
6pahA-4ml9A:
21.34