SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA606_1 (CHITINASE A)	4mlk	CT584 PROTEIN (Chlamydia trachomatis)	4 / 7	GLY A 31 ASP A 93 TYR A 32 ARG A 97	None	1.21A	3arrA-4mlkA: 2.7	3arrA-4mlkA: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARU_A_PNXA606_1 (CHITINASE A)	4mlk	CT584 PROTEIN (Chlamydia trachomatis)	4 / 7	GLY A 31 ASP A 93 TYR A 32 ARG A 97	None	1.19A	3aruA-4mlkA: undetectable	3aruA-4mlkA: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_A_ACTA5_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	4mlk	CT584 PROTEIN (Chlamydia trachomatis)	3 / 3	LYS A 23 SER A 79 GLN A 83	None	1.17A	3si7A-4mlkA: undetectable	3si7A-4mlkA: 25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KLA_A_ACTA1505_0 (MATERNAL PROTEIN PUMILIO)	4mlk	CT584 PROTEIN (Chlamydia trachomatis)	3 / 3	HIS A 95 LYS A 92 PHE A 35	None	1.22A	5klaA-4mlkA: undetectable	5klaA-4mlkA: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_1 (WTFP-TAG,GP41)	4mlk	CT584 PROTEIN (Chlamydia trachomatis)	5 / 12	SER A 79 LYS A 64 ASN A 62 GLU A 58 LEU A 60	None	1.13A	5nwuA-4mlkA: undetectable	5nwuA-4mlkA: 13.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ARR_A_PNXA606_1","CHITINASE A","4mlk","CT584 PROTEIN","Chlamydia trachomatis",4,"GLY A  31;ASP A  93;TYR A  32;ARG A  97","None","1.21A","3arrA-4mlkA:2.7","3arrA-4mlkA:15.62"],["3ARU_A_PNXA606_1","CHITINASE A","4mlk","CT584 PROTEIN","Chlamydia trachomatis",4,"GLY A  31;ASP A  93;TYR A  32;ARG A  97","None","1.19A","3aruA-4mlkA:undetectable","3aruA-4mlkA:15.62"],["3SI7_A_ACTA5_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","4mlk","CT584 PROTEIN","Chlamydia trachomatis",3,"LYS A  23;SER A  79;GLN A  83","None","1.17A","3si7A-4mlkA:undetectable","3si7A-4mlkA:25.69"],["5KLA_A_ACTA1505_0","MATERNAL PROTEIN PUMILIO","4mlk","CT584 PROTEIN","Chlamydia trachomatis",3,"HIS A  95;LYS A  92;PHE A  35","None","1.22A","5klaA-4mlkA:undetectable","5klaA-4mlkA:20.64"],["5NWU_A_ACAA18_1","WTFP-TAG,GP41","4mlk","CT584 PROTEIN","Chlamydia trachomatis",5,"SER A  79;LYS A  64;ASN A  62;GLU A  58;LEU A  60","None","1.13A","5nwuA-4mlkA:undetectable","5nwuA-4mlkA:13.53"]]