SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 LEU A 176
MET A 198
ALA A  72
LEU A  75
PHE A 139
 None
 1.19A 1gs4A-4mllA:
undetectable		 1gs4A-4mllA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 ILE A 179
PHE A 232
GLY A 231
ILE A  71
ALA A  72
 None
 1.26A 1mrgA-4mllA:
undetectable		 1mrgA-4mllA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		4 / 8 TYR A 241
LEU A  40
ASN A 273
ALA A  52
 None
 1.00A 2bnnA-4mllA:
undetectable
2bnnB-4mllA:
undetectable		 2bnnA-4mllA:
22.64
2bnnB-4mllA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		4 / 5 PHE A  69
THR A 124
LEU A 129
ALA A 159
 None
 1.37A 2e1qD-4mllA:
undetectable		 2e1qD-4mllA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 PHE A  69
LEU A 184
LEU A  75
ALA A  72
PHE A 175
 None
 1.20A 2vcvD-4mllA:
undetectable		 2vcvD-4mllA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 PHE A  69
LEU A 184
LEU A  75
ALA A  72
PHE A 175
 None
 1.27A 2vcvH-4mllA:
undetectable		 2vcvH-4mllA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
 None
 1.27A 2vdyA-4mllA:
undetectable		 2vdyA-4mllA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
 None
 1.27A 2vdyB-4mllA:
undetectable		 2vdyB-4mllA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 ALA A 215
PHE A  29
GLY A  36
SER A 258
ALA A 261
 1S6  A 301 (-3.7A)
None
None
1S6  A 301 (-2.4A)
None
 1.35A 2vh3A-4mllA:
undetectable		 2vh3A-4mllA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
 None
 1.33A 4c49B-4mllA:
undetectable		 4c49B-4mllA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
 None
 1.31A 4c49C-4mllA:
undetectable		 4c49C-4mllA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
 None
 1.26A 4c49D-4mllA:
undetectable		 4c49D-4mllA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 10 SER A 115
LYS A 212
THR A 213
GLY A 214
ALA A 215
 1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 (-3.7A)
 0.66A 4fh2A-4mllA:
19.4		 4fh2A-4mllA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 SER A 115
THR A 213
GLY A 214
ALA A 215
GLY A 216
 1S6  A 301 (-2.9A)
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 (-3.7A)
1S6  A 301 ( 3.7A)
 0.44A 4pm9A-4mllA:
20.5		 4pm9A-4mllA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 LEU A 161
GLY A 214
GLY A 227
ASN A 226
GLU A 230
 1S6  A 301 ( 4.3A)
1S6  A 301 (-3.3A)
None
None
None
 1.30A 4x61A-4mllA:
undetectable		 4x61A-4mllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 ILE A 179
PHE A 232
GLY A 231
ILE A  71
ALA A  72
 None
 1.31A 4yp2B-4mllA:
undetectable		 4yp2B-4mllA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		4 / 7 PHE A 243
ILE A 233
PHE A 229
GLY A 211
 None
 0.85A 4zdzA-4mllA:
undetectable		 4zdzA-4mllA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		4 / 7 PHE A 243
ILE A 233
PHE A 229
GLY A 211
 None
 0.80A 4ze3A-4mllA:
undetectable		 4ze3A-4mllA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 9 ILE A 179
PHE A 232
GLY A 231
ILE A  71
ALA A  72
 None
 1.31A 5cf9B-4mllA:
undetectable		 5cf9B-4mllA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		4 / 8 PHE A 243
ILE A 233
PHE A 229
GLY A 211
 None
 0.83A 5esjA-4mllA:
undetectable		 5esjA-4mllA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 ILE A 167
TYR A 141
THR A 219
ALA A  72
SER A 258
 None
None
None
None
1S6  A 301 (-2.4A)
 1.16A 5iwuA-4mllA:
undetectable		 5iwuA-4mllA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 TYR A 141
THR A 219
PHE A  69
ALA A  72
SER A 258
 None
None
None
None
1S6  A 301 (-2.4A)
 0.94A 5iwuA-4mllA:
undetectable		 5iwuA-4mllA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.73A 6b5yB-4mllA:
19.6		 6b5yB-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.76A 6b5yD-4mllA:
19.5		 6b5yD-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.73A 6b69A-4mllA:
19.6
6b69B-4mllA:
19.5		 6b69A-4mllA:
12.33
6b69B-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.73A 6b69D-4mllA:
19.3		 6b69D-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.67A 6b6aB-4mllA:
19.6		 6b6aB-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.72A 6b6aD-4mllA:
19.4		 6b6aD-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.82A 6b6cA-4mllA:
19.7		 6b6cA-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.63A 6b6dA-4mllA:
19.5		 6b6dA-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		6 / 12 SER A  67
SER A 115
LYS A 212
THR A 213
GLY A 214
GLY A 216
 1S6  A 301 (-1.3A)
1S6  A 301 (-2.9A)
None
1S6  A 301 (-3.6A)
1S6  A 301 (-3.3A)
1S6  A 301 ( 3.7A)
 0.75A 6b6eA-4mllA:
19.7		 6b6eA-4mllA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 4mll BETA-LACTAMASE OXA-1
(Escherichia
coli) 		5 / 12 GLN A 125
VAL A 116
GLY A 128
ALA A  77
ALA A  80
 None
 1.00A 6c2mC-4mllA:
undetectable		 6c2mC-4mllA:
15.51